Rchr
J-GLOBAL ID：202201008758380795
Update date: Jan. 12, 2024
Darwish Mohamed
Darwish Mohamed | Darwish Mohamed
Affiliation and department：
Research keywords (1)：
Brain development, neurodevelopmental disorders, Alternative splicing, Genome editing
Research theme for competitive and other funds (2)：
- 2022 - 2025 Establishment of specific inhibitory neuronal subtype differentiation and cell transplantation for the treatment of developmental disorders
- 2023 - 2025 Exploring a novel molecular pathway that underlies cerebellar contribution to autism spectrum disorder
Papers (10)：
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Mohamed Darwish, Satoko Suzuki, Yuki Ogawa, Akinori Takase, Masami Tanaka, Yoko Iijima, Yuji Sato, Mariko Suzuki, Yumi Kanegae, Chisa Okada, et al. Activity-regulated micro-exon splicing programs underlie late-onset plasticity at the axon initial segment. 2023
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Hideo Hagihara, Hirotaka Shoji, Satoko Hattori, Giovanni Sala, Yoshihiro Takamiya, Mika Tanaka, Masafumi Ihara, Mihiro Shibutani, Izuho Hatada, Kei Hori, et al. Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment. 2023
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Mohamed Darwish, Masatoshi Ito, Yoko Iijima, Akinori Takase, Noriko Ayukawa, Satoko Suzuki, Masami Tanaka, Kanae Komori, Daisuke Kaida, Takatoshi Iijima. Neuronal SAM68 differentially regulates alternative last exon splicing and ensures proper synapse development and function. Journal of Biological Chemistry. 2023. 105168-105168
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Mohamed Darwish, Satoko Hattori, Hirofumi Nishizono, Tsuyoshi Miyakawa, Nozomu Yachie, Keizo Takao. Comprehensive behavioral analyses of mice with a glycine receptor alpha 4 deficiency. Molecular brain. 2023. 16. 1. 44-44
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Yuji Sato, Yoko Iijima, Mohamed Darwish, Tadayuki Sato, Takatoshi Iijima. Distinct Expression of SLM2 Underlies Splicing-Dependent Trans-Synaptic Signaling of Neurexin Across GABAergic Neuron Subtypes. Neurochemical research. 2022. 47. 9. 2591-2601
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Lectures and oral presentations (6)：
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Exploring a novel molecular pathway underlies cerebellar development and autism spectrum disorder
(The 46th Annual Meeting of the Japan Neuroscience Society 2023)
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Exploring a novel molecular pathway underlies cerebellar development and autism spectrum disorder
(The 64th Annual Meeting of the Japanese Society of Neuropathology /The 66th Annual Meeting of the Japanese Society of Neurochemistry 2023)
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Investigation into the role of Glra4, a functionally unknown subunit of glycine receptors, in brain function and neurological disorders
(The 42nd Annual Meeting of the Japan Neuroscience Society 2019)
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Generation of Glycine Receptor Alpha 4 knockout Mice Using High-efficient Modified CRISPR-Cas9 Protocol
(The Platform of Advanced Animal Model Support 2019)
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Generation of Glycine Receptor Alpha 4 knockout Mice Using High-efficient Modified CRISPR-Cas9 Protocol
(The 17th Annual meeting of Molecular and Cellular Cognition Society 2018)
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Works (4)：
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Lecturer of Biochemistry
Faculty of Pharmacy, Cairo University, Egypt 2022 - 現在
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Postdoctoral researcher
Tokai University, Japan 2021 - 現在
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Teaching and research assistant at the Biochemistry Department
Faculty of Pharmacy, Cairo University, Egyp 2015 - 2017
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Clinical Pharmacist
2013 - 2014
Education (2)：
- 2017 - 2021 University of Toyama Graduate School of Innovative Life Science
- 2009 - 2013 Faculty of Pharmacy, Cairo University
Work history (3)：
- 2021/04 - 現在 Tokai University Department of Molecular Life Science
- 2017/02 - 2021/03 University of Toyama
- 2015/01 - 2017/01 Cairo University Biochemistry Department
Awards (6)：
Association Membership(s) (4)：
The Japanese Society for Neurochemistry
, The Japan Neuroscience Society
, The International Society for Trenchless Technology
, Society for Neuroscience
