Rchr
J-GLOBAL ID:202201009416369796   Update date: May. 08, 2024

Ikeda Keisuke

イケダ ケイスケ | Ikeda Keisuke
Affiliation and department:
Research field  (1): Pharmaceuticals - analytical and physicochemistry
Research keywords  (3): ペプチド ,  アミロイド ,  生体膜
Research theme for competitive and other funds  (6):
  • 2022 - 2026 Development of Molecules Inducing Disruption of Cell Membrane Asymmetry and Search for Endoplasmic Reticulum Lipid Scrambling Factors
  • 2020 - 2023 脂質-ペプチドナノ粒子を用いた標的細胞膜への膜タンパク質デリバリー技術の開発
  • 2017 - 2021 Comprehensive understanding of the phospholipid flip mechanism in the endoplasmic reticulum and establishment of the control technology of biomembrane dynamics
  • 2016 - 2018 Aggregation of amyloid-beta protein on size-controlled lipid nanoparticles
  • 2014 - 2017 Elucidation of dynamic control of biomembrane functions by phospholipid transfer proteins
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Papers (47):
  • Keisuke Ikeda, Yuuki Sugiura, Hiroyuki Nakao, Minoru Nakano. Thermodynamics of oligomerization and Helix-to-sheet structural transition of amyloid β-protein on anionic phospholipid vesicles. Biophysical chemistry. 2024. 310. 107248-107248
  • Hiroyuki Nakao, Michihiro Nagao, Takeshi Yamada, Koki Imamura, Koichi Nozaki, Keisuke Ikeda, Minoru Nakano. Impact of transmembrane peptides on individual lipid motions and collective dynamics of lipid bilayers. Colloids and Surfaces B: Biointerfaces. 2023. 228. 113396-113396
  • Motomi Matsuda, Keisuke Ikeda, Tomoshi Kameda, Hiroyuki Nakao, Minoru Nakano. Fine-Tuning and Enhancement of pH-Dependent Membrane Permeation of Cyclic Peptides by Utilizing Noncanonical Amino Acids with Extended Side Chains. Journal of medicinal chemistry. 2023
  • Ayari Miyajima, Hiroyuki Nakao, Keisuke Ikeda, Minoru Nakano. The Nanometer-Scale Proximity of Bilayers Facilitates Intermembrane Lipid Transfer. The journal of physical chemistry letters. 2023. 4172-4178
  • Kiyoto Kamagata, Atsumi Hando, Maulana Ariefai, Nanako Iwaki, Saori Kanbayashi, Ryotaro Koike, Keisuke Ikeda. Rational design of phase separating peptides based on phase separating protein sequence of p53. Scientific reports. 2023. 13. 1. 5648-5648
more...
MISC (102):
  • 清水裕道, 中尾裕之, 池田恵介, 中野実. Phosphatidylserine externalization in the plasma membrane by transmembrane peptides. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 池田恵介. Interactions between Intra- and Extracellular Vesicles and Amyloid- β Protein : Promotion of Fibril Formation by Highly Curved Lipid Membranes. 膜. 2021. 46. 1
  • 来見田遥一, 小林海渡, 齋藤裕, 齋藤裕, 中道優介, 池田恵介, 亀田倫史. MDシミュレーションと機械学習を組み合わせたペプチド凝集傾向予測. 日本蛋白質科学会年会プログラム・要旨集. 2021. 21st
  • 松田幹望, 池田恵介, 中尾裕之, 中野実. Effect of side chain length of acidic amino acids on pH-dependent binding, insertion, and permeation of cyclic peptides into lipid membranes. 日本膜学会年会講演要旨集(CD-ROM). 2021. 43rd
  • 中尾裕之, 木村優介, 池田恵介, 中野実. Induction of phagocytosis by lipid flip-flop promoting peptides. 日本膜学会年会講演要旨集(CD-ROM). 2021. 43rd
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Professional career (1):
  • Ph. D (Kyoto University)
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