Obata Honoka

オバタホノカ | Obata Honoka

Affiliation and department：
Job title： Researcher

Research field (1)： Radiology

Research theme for competitive and other funds (3)：

2024 - 2026 がん染色体不安定性がつくる慢性炎症状態と治療応答性の関係解明
2022 - 2025 Development of radioplatinum compounds targeting dysregulated genomic factors
2020 - 2023 次世代標的アイソトープ療法の開拓に向けたオージェ電子治療の効果検証

Papers (18)：

Honoka Obata, Atsushi B Tsuji, Hitomi Sudo, Aya Sugyo, Kaori Hashiya, Hayato Ikeda, Masatoshi Itoh, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, et al. Novel Auger-Electron-Emitting 191Pt-Labeled Pyrrole-Imidazole Polyamide Targeting MYCN Increases Cytotoxicity and Cytosolic dsDNA Granules in MYCN-Amplified Neuroblastoma. Pharmaceuticals (Basel, Switzerland). 2023. 16. 11
Honoka Obata, Mikako Ogawa, Michael R Zalutsky. DNA Repair Inhibitors: Potential Targets and Partners for Targeted Radionuclide Therapy. Pharmaceutics. 2023. 15. 7
Honoka Obata, Akihiro Kurimasa, Tadanori Muraoka, Atsushi B Tsuji, Katsuya Kondo, Yoshikazu Kuwahara, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang. Dynamic imaging analysis reveals Auger electron-emitting radio-cisplatin induces DNA damage depending on the cell cycle. Biochemical and biophysical research communications. 2022. 637. 286-293
Honoka Obata, Atsushi B Tsuji, Hitomi Sudo, Aya Sugyo, Katsuyuki Minegishi, Kotaro Nagatsu, Mikako Ogawa, Ming-Rong Zhang. Precise quantitative evaluation of pharmacokinetics of cisplatin using a radio-platinum tracer in tumor-bearing mice. Nuclear medicine communications. 2022. 43. 11. 1121-1127
Kotaro Nagatsu, Tomoyuki Ohya, Honoka Obata, Kazutoshi Suzuki, Ming-Rong Zhang. Special radionuclide production activities - recent developments at QST and throughout Japan. Radiochimica Acta. 2022. 110. 6-9. 751-763

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MISC (9)：

尾幡穂乃香, 尾幡穂乃香, 辻厚至, 永津弘太郎, 小川美香子, ZHANG Ming Rong. Development of ¹⁹¹Pt-labeled compounds inducing DNA damage efficiently. 日本薬学会年会要旨集(Web). 2023. 143rd
武井誠, 鈴木寿, 橋本裕輝, 峯岸克行, 尾幡穂乃香, 栗原雄祐, 小川政直, 大久保崇之, 塚越海渡, 念垣信樹, et al. Production and Development of Radiopharmaceuticals Using Cyclotron in 2021. 量子科学技術研究開発機構資料(Web). 2022. 38
尾幡穂乃香, 尾幡穂乃香, 永津弘太郎, 辻厚至, 小川美香子, ZHANG Ming-Rong. Cyclotron production of ¹⁹¹Pt and radiosynthesis of ¹⁹¹Pt-labeled-compounds. アイソトープ・放射線研究発表会(Web). 2021. 1. 119
尾幡穂乃香, 尾幡穂乃香, 辻厚至, 永津弘太郎, 小川美香子, 張明栄. [^189,191Pt]cisplatinの薬剤分布とDNA障害性の評価. 核医学(Web). 2021. 58. Supplement
松岡慶太郎, 尾幡穂乃香, 尾幡穂乃香, 永津弘太郎, 小島正寛, 吉野達彦, 小川美香子, 小川美香子, 松永茂樹, 松永茂樹. アリールヨードニウムイリドを用いた求核的アスタチン標識反応の開発. 反応と合成の進歩シンポジウム講演要旨集. 2021. 47th

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Education (3)：

Professional career (1)：

Work history (4)：

Awards (8)：

2023/10 - 第9回北海道大学部局横断シンポジウムベストプレゼンテーター賞
2023/03 - The 143rd Annual Meeting of the Pharmaceutical Society of Japan Best Student Presentation Award
2023/03 - Hokkaido University Ohtsuka Memorial Award
2021/09 - The 4th Council of Radiopharmaceutical Sciences, Japanese Society of Nuclear Medicine Young Investigator Award
2021/07 - The 58th Annual Meeting on Radioisotopes and Radiation Researches Young Investigator Award

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