Hojo Keiko

ホウジョウケイコ | Hojo Keiko

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (6)： stapled peptide , aqueous peptide synthesis , microwave assisted synthesis , solid-phase synthesis , green sustainable chemistry , peptide

Research theme for competitive and other funds (12)：

2016 - 2019 Design of the active site-directed plasmin inhibitor oriented to the clinical applications
2016 - 2019 Discovery of INSL7 analogue with agonistic activity for RXFP3 in the brai
2016 - 2019 リラキシン-3の構造に指南されたペプチド性抗うつ薬の開発研究
2016 - 2019 RXFP3を標的とする肥満症治療薬の開発
2012 - 2017 創剤・創薬・創材支援を企図した医用なのパティキュレートシステム基盤研究拠点形成

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Papers (44)：

Keiko Hojo, Yuki Manabe, Tomoyo Uda, Yuko Tsuda. Water-Based Solid-Phase Peptide Synthesis without Hydroxy Side Chain Protection. JOURNAL OF ORGANIC CHEMISTRY. 2022
Keiko Hojo, Suzuko Fujiwara, Hoshito Inai, Yuki Manabe, Yuko Tsuda. Environmentally Conscious In-Water Peptide Synthesis Using Boc Strategy. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 2022. 28. 2
Yuko Tsuda, Koushi Hidaka, Keiko Hojo, Yoshio Okada. Exploration of Active Site-Directed Plasmin Inhibitors: Beyond Tranexamic Acid. PROCESSES. 2021. 9. 2
Yuko Tsuda, Koushi Hidaka, Keiko Hojo, Keigo Gohda, Naoki Teno, Keiko Wanaka. Design of new cyclic plasmin inhibitors. JOURNAL OF PEPTIDE SCIENCE. 2018. 24. S117-S118
Keiko Hojo, Mohammed Akhter Hossain, Julien Tailhades, Fazel Shabanpoor, Lilian L L Wong, Emma E K Ong-Pålsson, Hanna E Kastman, Sherie Ma, Andrew L Gundlach, K Johan Rosengren, et al. Development of a Single-Chain Peptide Agonist of the Relaxin-3 Receptor Using Hydrocarbon Stapling. Journal of medicinal chemistry. 2016. 59. 16. 7445-56

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MISC (24)：

北條恵子, 北條恵子, 日高興史, 日高興史, 市川秀喜, 市川秀喜, 津田裕子, 津田裕子. Aqueous MW-assisted solid-phase peptide synthesis ~ a trial of peptide synthesis without protection II. 日本薬学会年会要旨集(CD-ROM). 2020. 140th
福本哲也, 北條恵子, 北條恵子, 日高興士, 日高興士, 屋山勝俊, 屋山勝俊, 津田裕子, 津田裕子. Relaxin-2B鎖のステープルアナログの設計と合成. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
北條恵子, 日高興士, 市川秀喜, 津田裕子, 北條恵子, 日高興士, 市川秀喜, 津田裕子. 水中マイクロ波ペプチド固相合成~水酸基無保護下でのペプチド合成. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
北條恵子, HOSSAIN Akhter, BATHGATE Ross, 日高興士, 津田裕子, WADE John. リラキシン受容体(RXFP3)アンタゴニスト活性を有するリラキシン3アナログの設計と合成. 日本薬学会年会要旨集(CD-ROM). 2017. 137th
北條恵子, BATHGATE Ross AD, ROSENGREN K Johan, GUNDLACH Andrew L, 日高興士, 藤岡志緒, 津田裕子, HOSSAIN Mohammad Akhter, HOSSAIN Mohammad Akhter, WADE John D. RXFP3選択的アゴニスト~Relaxin-3ステープルヘリックスアナログの開発. メディシナルケミストリーシンポジウム講演要旨集. 2015. 33rd

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Work history (3)：

2024/04 - 現在 Kobe Gakuin University The Faculty of Pharmaceutical Sciences Lecture
2007/04 - 2024/03 Kobe Gakuin University The Faculty of Pharmaceutical Sciences Assistant Professor
2013/09 - 2014/10 The University of Melbourne Florey Neurosciense Institute Research Fellow

Awards (3)：

2016/01 - Takeda Science Foundation 8th Takeda Science Foundation Symposium on PharmaSciences Excellent Poster Award Design, synthesis, and Biological Activity of Stapled Single-Chain Peptide Agonist for the Relaxin -3 Receptor
2008/10 - The Japanese Peptide Society The Japanense Peptide Society Award for Young Investigator Development of solid-pahse peptide synthesis in water
2003/11 - Korean Peptide Society 7th Korean Peptide Symposium Young Scientist Award Solid-phase peptide synthesis in water using water-soluble protecting group

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