Research theme for competitive and other funds (1)：
酸性がん微小環境に対する阻害剤が免疫細胞の抗腫瘍効果に与える影響の解明
Papers (4)：
Takanobu Nadai, Katsuya Narumi, Yuto Mukai, Hinata Ueda, Ayako Furugen, Yoshitaka Saito, Masaki Kobayashi. 5-Oxoproline Enhances 4-Hydroxytamoxifen-induced Cytotoxicity by Increasing Oxidative Stress in MCF-7 Breast Cancer Cells. Anticancer research. 2023. 43. 3. 1113-1120
Yuto Mukai, Atsushi Yamaguchi, Tomoya Sakuma, Takanobu Nadai, Ayako Furugen, Katsuya Narumi, Masaki Kobayashi. Involvement of <i>SLC16A1</i> /MCT1 and <i>SLC16A3</i> /MCT4 in <scp>l</scp> -lactate transport in the hepatocellular carcinoma cell line. Biopharmaceutics & Drug Disposition. 2022. 43. 5. 183-191
Yuka Takahashi, Katsuya Narumi, Takanobu Nadai, Hinata Ueda, Taiki Yamamura, Ayako Furugen, Masaki Kobayashi. In vitro and in vivo evaluation of organic anion-transporting polypeptide 2B1-mediated pharmacokinetic interactions by apple polyphenols. Xenobiotica. 2021. 51. 11. 1318-1325
Takanobu Nadai, Katsuya Narumi, Ayako Furugen, Yoshitaka Saito, Ken Iseki, Masaki Kobayashi. Pharmacological Inhibition of MCT4 Reduces 4-Hydroxytamoxifen Sensitivity by Increasing HIF-1α Protein Expression in ER-Positive MCF-7 Breast Cancer Cells. Biological and Pharmaceutical Bulletin. 2021. 44. 9. 1247-1253
The potential of MCT4 and NHE1 inhibitors for PD-L1 protein expression targeting the microenvironment
(The 144th Annual Meeting of the Pharmaceutical Society of Japan 2024)
PXR antagonists decrease the MRP2 protein expression in cisplatin resistance cells
(The 144th Annual Meeting of the Pharmaceutical Society of Japan 2024)
2018 - 2022 Hokkaido University Graduate School of Life Science
2012 - 2018 Aichi Gakuin University School of Pharmacy Department of Pharmaceutical Health Care and Science
Work history (4)：
2024/04 - 現在 Cincinnati Children's Hospital Medical Center Translational and Clinical Pharmacology Research Fellow
2022/08 - 2024/03 Kobe Gakuin University The Faculty of Pharmaceutical Sciences Department of Pharmacy
2022/04 - 2022/07 Hokkaido University Faculty of Pharmaceutical Sciences
2020/04 - 2022/03 Hokkaido University Graduate School of Life Science
Awards (2)：
2022/07 - 日本学生支援機構 特に優れた業績による返還免除(半額免除)
2018/08 - 愛知学院大学 卒業研究発表会優秀賞
Association Membership(s) (5)：
日本TDM学会
, American Society for Clinical Pharmacology and Therapeutics
, International Association of Therapeutic Drug Monitoring and Clinical Toxicology
, 日本薬学会
, 日本薬剤学会
