Yoshimatsu Yuki

Affiliation and department：

Research keywords (2)： sarcoma , Patient-derived cancer models

Research theme for competitive and other funds (7)：

2022 - 2025 がんモデルとプロテオゲノミクスを用いた隆起性皮膚線維肉腫の新規治療法の開発
2022 - 2025 肉腫におけるトラベクテジンの奏効性と融合遺伝子の相関の分子背景を調べる研究
2021 - 2024 Discovery of innovative seeds for diagnosis and treatment in bone and soft-tissue sarcomas by proteogenomic approach
2018 - 2022 CMTM6 stabilizes PD-L1 expression and regulates its metastasis in Ewing's sarcoma
2020 - 2022 Research Using Patient-Derived "Rare Cancer" Models to Overcome the Limitations of Cancer Genomic Medicine

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Papers (84)：

Yuki Yoshimatsu, Rei Noguchi, Julia Osaki, Yooksil Sin, Ryuto Tsuchiya, Takuya Ono, Taro Akiyama, Yuki Adachi, Yoshikazu Tanzawa, Akihiko Yoshida, et al. Establishment and characterization of NCC-LMS3-C1: a novel patient-derived cell line of leiomyosarcoma. Human cell. 2024. 37. 1. 337-344
Rei Noguchi, Yuki Yoshimatsu, Yooksil Sin, Takuya Ono, Ryuto Tsuchiya, Hiroshi Yoshida, Tohru Kiyono, Yutaka Yonemura, Tadashi Kondo. Establishment and characterization of NCC-PMP2-C1: a novel patient-derived cell line of pseudomyxoma peritonei with signet ring cells. Human Cell. 2023. 37. 2. 511-522
Takuya Ono, Rei Noguchi, Julia Osaki, Taro Akiyama, Yuki Adachi, Naoki Kojima, Yu Toda, Suguru Fukushima, Yuki Yoshimatsu, Akihiko Yoshida, et al. Establishment and characterization of NCC-DFSP5-C1: a novel patient-derived dermatofibrosarcoma protuberans cell line. 2023
Rei Noguchi, Yuki Yoshimatsu, Yooksil Sin, Takuya Ono, Ryuto Tsuchiya, Hiroshi Yoshida, Tohru Kiyono, Yutaka Yonemura, Tadashi Kondo. Correction: Noguchi et al. Establishment and Characterization of NCC-PMP1-C1: A Novel Patient-Derived Cell Line of Metastatic Pseudomyxoma Peritonei. J. Pers. Med. 2022, 12, 258. Journal of personalized medicine. 2023. 13. 9
Takuya Ono, Rei Noguchi, Yuki Yoshimatsu, Yooksil Sin, Ryuto Tsuchiya, Taro Akiyama, Naoki Kojima, Yu Toda, Chiaki Sato, Suguru Fukushima, et al. Establishment and characterization of two novel patient-derived cell lines from giant cell tumor of bone. Human cell. 2023. 36. 5. 1804-1812

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MISC (20)：

Ono Takuya, Ono Takuya, Noguchi Rei, Yoshimatsu Yuki, Sin Yooksil, Kojima Nobuhiko, Kondo Tadashi. Development of different organ derived decellularized tissue gels that support in vitro tumor cell behavior in a tumor type-specific manner. Journal of Electrophoresis (Web). 2021. 65. 1
土屋流人, 土屋流人, 野口玲, 吉松有紀, SIN Y., 小野拓也, 清茜, 小迫英尊, 川井章, 近藤格. Novel candidate drugs for the treatment of Malignant peripheral nerve sheath tumor revealed by mass spectrometry and drug screening using patient-derived cell lines. 日本プロテオーム学会大会プログラム・抄録集. 2021. 2021 (CD-ROM)
野口玲, 吉松有紀, SIN Y, 小野拓也, 土屋流人, 小迫英尊, 近藤格. OncoProGx~innovative software generating sample-specific database for proteogenomics. 日本プロテオーム学会大会プログラム・抄録集. 2021. 2021 (CD-ROM)
土屋流人, 土屋流人, 野口玲, 吉松有紀, 申育實, 小野拓也, 清茜, 小迫英尊, 川井章, 近藤格. プロテオーム解析と患者由来肉腫細胞株により同定した悪性末梢神経鞘腫の新規治療薬候補. 電気泳動(Web). 2021. 65. Suppl
申育實, 野口玲, 吉松有紀, 土屋流人, 小野拓也, 清茜, 桑田優, 菅谷潤, 川井章, 近藤格. 悪性末梢神経鞘腫瘍の患者由来細胞株NCC-MPNST6-C1の樹立. 電気泳動(Web). 2021. 65. Suppl

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Books (2)：

Tumor Marker Guidelines
2021
“希少がんーがん診療の新たな課題-”
日本臨牀 79巻増刊号1(2021年3月31日刊行)

Professional career (1)：

Molecular Pathology (The University of Tokyo)

Work history (4)：

2022/04 - 現在地方独立行政法人栃木県立がんセンター
2016/09 - National Cancer Center
2012/09 - University of Washington Medicine (Seattle, USA) senior fellow
2010/04 - Fred Hutchinson Cancer Research Center (Seattle, USA) Postdoctoral Fellow

Awards (3)：

2023/08 - 日本ヒト細胞学会学術集会優秀演題賞平滑筋肉腫の細胞株の樹立とその性状の解析および薬効評価スクリーニング
2021/11 - 患者由来がんモデル研究会ポスター賞「患者由来「肉腫」モデルの構築」
2010/03 - 2009 Overseas Study Grant (12th Edition) FredHuchinson Cancer Research Center USA Seattle 2010.4.1〜2012.3.31

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