Rchr
J-GLOBAL ID：202201015251938260
Update date: Aug. 26, 2024
Tsukahara Takao
ツカハラ タカオ | Tsukahara Takao
Affiliation and department：
Job title：
Assitant Professor
Research field (3)：
Nervous system function
, Genomics
, Neuroanatomy and physiology
Research keywords (5)：
エピジェネティクス
, Bioinformatics
, patch clamp
, Smith-Magenis syndrome
, Neurophysiology
Research theme for competitive and other funds (6)：
Papers (13)：
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Takao Tsukahara, Saini Kethireddy, Katherine Bonefas, Alex Chen, Brendan LM Sutton, Yali Dou, Shigeki Iwase, Michael A Sutton. Division of labor among H3K4 Methyltransferases Defines Distinct Facets of Homeostatic Plasticity. 2023
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Pilar Rivero-Ríos, Takao Tsukahara, Tunahan Uygun, Alex Chen, Garrett D. Chavis, Sai Srinivas Panapakkam Giridharan, Shigeki Iwase, Michael A. Sutton, Lois S. Weisman. Recruitment of the SNX17-Retriever recycling pathway regulates synaptic function and plasticity. Journal of Cell Biology. 2023. 222. 7
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Patricia M. Garay, Alex Chen, Takao Tsukahara, Jean Carlos Rodríguez Díaz, Rafi Kohen, J. Christian Althaus, Margarete A. Wallner, Roman J. Giger, Kevin S. Jones, Michael A. Sutton, et al. RAI1 Regulates Activity-Dependent Nascent Transcription and Synaptic Scaling. Cell Reports. 2020. 32. 6. 108002-108002
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Rafi Kohen, Katherine T. Baldwin, Patricia Marie Garay, Takao Tsukahara, Alex Chen, Corey G. Flynn, Craig Johnson, Xiaofeng Zhao, Michael A. Sutton, Shigeki Iwase, et al. Small-hairpin RNAs cause target-independent microRNA dysregulation in neurons and elicit global transcriptomic changes. 2020
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Minami Furukawa, Takao Tsukahara, Kazuo Tomita, Haruki Iwai, Takahiro Sonomura, Shouichi Miyawaki, Tomoaki Sato. Neonatal maternal separation delays the GABA excitatory-to-inhibitory functional switch by inhibiting KCC2 expression. Biochemical and Biophysical Research Communications. 2017. 493. 3. 1243-1249
ｍore...
MISC (9)：
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Pilar Rivero-Rios, Takao Tsukahara, Tunahan Uygun, Alex Chen, Garrett Chavis, Sai Giridharan, Shigeki Iwase, Michael Sutton, Lois Weisman. RECRUITMENT OF THE SNX17-DEPENDENT ENDOMEMBRANE RECYCLING PATHWAY REGULATES SYNAPTIC PLASTICITY. IBRO Neuroscience Reports. 2023. 15. S333-S333
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古川 みなみ, 塚原 飛央, 宮脇 正一, 佐藤 友昭. 幼少期ストレスと発達性障害との関係解明 矯正治療の効率化に向けた検討. 日本矯正歯科学会大会プログラム・抄録集. 2017. 76回. 158-158
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古川 みなみ, 塚原 飛央, 富田 和男, 高 裕子, 佐藤 友昭. 母子分離ストレスは雄性マウスにおいてGABAスイッチの時期を遅らせ、発達性障害様行動異常を誘発する. Journal of Oral Biosciences Supplement. 2017. 2017. 380-380
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塚原 飛央, 古川 みなみ, 富田 和男, 岩井 治樹, 高 裕子, 薗村 貴弘, 佐藤 友昭. ストレスによるGPR30過剰発現はAkt-WNK1の過敏反応を惹起し、KCC2を不活化させることで、GABA抑制機能を低下させる. Journal of Oral Biosciences Supplement. 2017. 2017. 379-379
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Takao Tsukahara, Haruki Iwai, Masaaki Masuhara, Tomoaki Sato. 17alfa-estradiol prevents gamma-aminobutyric signaling dysfunction induced by repeated stress in the hippocampus associated with behavioral abnormalities via G-protein-coupled estrogen receptor in ovariectomized mice. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2016. 19. 248-249
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Lectures and oral presentations (7)：
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Emerging Roles of RAI1 in Neuronal Transcription and Synaptic Plasticity
(11th PRISMS Research Symposium 2024)
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Deciphering the Role of Kdm5c/Kdm5d X-Y Pair genes in neurodevelopmental disorders
(NIPS meeting on synapse physiology 2023)
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H3K4 Methylation Writer Enzymes and Their Role in Synaptic Scaling
(UM Human Genetics Postdoctoral Symposium 2022)
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RAI1 Regulates Gene Expression Program for Homeostatic Plasticity
(10th SMS Research Symposium 2019)
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Roles of RAI1 in Translating the Histone Methylation Code into Synaptic plasticity
(PRISMS 10th International SMS Conference 2018)
ｍore...
Education (2)：
- 2012 - 2016 Kagoshima University Graduate School of Medical and Dental Sciences
- 2005 - 2011 Kagoshima University Department of Dentistry
Professional career (1)：
- PhD (Kagoshima University)
Work history (5)：
- 2023/10 - 現在 Meikai University
- 2018/01 - 2023/09 University of Michigan Medical School Research Fellow
- 2018/01 - 2020/03 PRISMS Postdoctoral Research Fellow
- 2015/12 - 2018/01 Kagoshima University Graduate School of Medical and Dental Sciences Assistant Professor
- 2011/04 - 2012/03 Kagoshima University Hospital
Awards (5)：
- 2018 - PRISMS(Parents and Researchers Interested in Smith-Magenis syndrome) PRISMS Postdoctoral Fellowship Award
- 2016 - 鹿児島大学大学院医歯学総合研究科 医歯学奨励賞
- 2016 - 鹿児島大学歯学部同窓会奨励賞
- 2014 - 鹿児島大学口腔先端科学教育研究センター(ERCAOS) 口腔先端科学 優秀賞
- 2012 - 鹿児島大学口腔先端科学教育研究センター(ERCAOS) 口腔先端科学 学術奨励賞
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