Rchr
J-GLOBAL ID：202201015975404283
Update date: Jul. 23, 2024
Hui Kelvin (Kai-Wan)
フイ ケルヴィン (カイ ワン) | Hui Kelvin (Kai-Wan)
Affiliation and department：
Job title：
Specially-appointed Junior Associate Professor
Research theme for competitive and other funds (3)：
- 2020 - 2023 Cell-type-specific proteome profiling of cortical GABAergic interneurons in monogenic mouse models of autism spectrum disorders
- 2014 - 2016 Proteomic analysis of activity-dependent protein translation and defects caused by autistic spectrum disorder (ASD)-related mutations
- 2011 - 2013 精神疾患における凝集性タンパク質の構造機能解析
Papers (20)：
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Kelvin K. Hui, Shinya Yamanaka. iPS cell therapy 2.0: Preparing for next-generation regenerative medicine. BioEssays. 2024
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Josephine W Thinwa, Zhongju Zou, Emily Parks, Salwa Sebti, Kelvin Hui, Yongjie Wei, Mohammad Goodarzi, Vibha Singh, Greg Urquhart, Jenna L Jewell, et al. CDKL5 regulates p62-mediated selective autophagy and confers protection against neurotropic viruses. The Journal of clinical investigation. 2024. 134. 1
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Ryo Endo, Yi-Kai Chen, John Burke, Noriko Takashima, Nayan Suryawanshi, Kelvin K Hui, Tatsuhiko Miyazaki, Motomasa Tanaka. Dysregulation of ribosome-associated quality control elicits cognitive disorders via overaccumulation of TTC3. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 12. e2211522120
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Kelvin K Hui, Maya Latif, Chesa Dojo Soeandy, Shudi Huang, Christopher E Rodgers, Andrew J Elia, Jeffrey T Henderson. Cisplatin toxicity in the developing brain displays an absolute requirement for caspase-3. Experimental neurology. 2022. 351. 114010-114010
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Kelvin K Hui, Ryo Endo, Akira Sawa, Motomasa Tanaka. A Perspective on the Potential Involvement of Impaired Proteostasis in Neuropsychiatric Disorders. Biological psychiatry. 2022. 91. 4. 335-345
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MISC (1)：
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パー・ニルソン, Hui Kelvin, 津吹 聡, 赤木 巧, 和泉 伸一, 小守 壽文, 田中 元雅, 齊藤 貴志, 岩田 修永, 西道 隆臣. 認知症研究におけるCell Biology I リソソーム・オートファジー アルツハイマー病におけるAβ分泌とオートファジーに依存するプラーク形成(Alzheimer's disease Aβ secretion and plaque formation depend on autophagy). Dementia Japan. 2014. 28. 4. 424-424
Education (2)：
- 2003 - 2010 University of Toronto Graduate Department of Pharmaceutical Sciences, Faculty of Pharmacy Doctorate of Philosophy (PhD), Pharmaceutical Sciences and Collaborative Program in Neuroscience
- 1999 - 2003 University of Toronto Department of Pharmacology, Faculty of Arts and Science Honours Bachelor of Science (HBSc), Pharmacology and Toxicology Double Specialist
Work history (3)：
- 2020/11 - 2022/08 Albert Einstein College of Medicine Department of Developmental and Molecular Biology
- 2020/01 - 2020/10 University of Texas Southwestern Medical Center/Howard Hughes Medical Institute Center for Autophagy Research, Department of Internal Medicine
- 2011/02 - 2019/12 RIKEN Brain Science Institute/Center for Brain Science Laboratory for Protein Conformation Diseases
Association Membership(s) (5)：
International Society for Stem Cell Research
, International Behavioral Neuroscience Society
, Canadian Association for Neuroscience
, The Japan Neuroscience Society
, Society for Neuroscience
