Mizuno Keiko

Research theme for competitive and other funds (7)：

2022 - 2025 治療抵抗性獲得に関与する小細胞肺癌機能性RNA分子アトラスの構築
2019 - 2024 マイクロRNAを起点とした肺扁平上皮癌に関する分子経路と新規治療法の探索研究
2019 - 2022 Devising drug repositioning based on functional RNA integration analysis of small cell lung cancer.
2019 - 2022 Exploration of molecular pathways for lung cancer with interstitial pneumonia and development of new treatments based on understanding of functional RNA integration
2017 - 2020 Development of innovative therapy for treatment-resistant small cell lung cancer based on functional RNA network analysis

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Papers (69)：

Yoko Hagihara, Yuya Tomioka, Takayuki Suetsugu, Masahiro Shinmura, Shunsuke Misono, Yusuke Goto, Naoko Kikkawa, Mayuko Kato, Hiromasa Inoue, Keiko Mizuno, et al. Identification of Tumor-Suppressive miR-139-3p-Regulated Genes: TRIP13 as a Therapeutic Target in Lung Adenocarcinoma. Cancers. 2023. 15. 23
Kengo Tanigawa, Yuya Tomioka, Shunsuke Misono, Shunichi Asai, Naoko Kikkawa, Yoko Hagihara, Takayuki Suetsugu, Hiromasa Inoue, Keiko Mizuno, Naohiko Seki. Minichromosome maintenance proteins in lung adenocarcinoma: Clinical significance and therapeutic targets. FEBS open bio. 2023
Yuya Tomioka, Takayuki Suetsugu, Naohiko Seki, Kengo Tanigawa, Yoko Hagihara, Masahiro Shinmura, Shunichi Asai, Naoko Kikkawa, Hiromasa Inoue, Keiko Mizuno. The Molecular Pathogenesis of Tumor-Suppressive miR-486-5p and miR-486-3p Target Genes: GINS4 Facilitates Aggressiveness in Lung Adenocarcinoma. Cells. 2023. 12. 14
Shunichi Asai, Yusuke Goto, Kengo Tanigawa, Yuya Tomioka, Mayuko Kato, Keiko Mizuno, Shinichi Sakamoto, Naohiko Seki. MiR-15b-5p inhibits castration-resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM3. FEBS letters. 2023. 597. 8. 1164-1175
Kengo Tanigawa, Shunsuke Misono, Keiko Mizuno, Shunichi Asai, Takayuki Suetsugu, Akifumi Uchida, Minami Kawano, Hiromasa Inoue, Naohiko Seki. MicroRNA signature of small cell lung cancer after treatment failure: impact on oncogenic targets by miR-30a-3p control. Molecular oncology. 2022

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MISC (111)：

冨岡勇也, 松山崇弘, 安田俊介, 大脇一人, 美園俊祐, 三山英夫, 末次隆行, 水野圭子, 井上博雅. 妊娠中に気管内に静脈瘤が観察されたKlippel-Trenaunay-Weber症候群の1例. 気管支学. 2022. 44. Suppl. S265-S265
松山洋美, 松山崇弘, 安田俊介, 冨岡勇也, 大脇一人, 美園俊祐, 近藤清貴, 三山英夫, 末次隆行, 水野圭子, et al. 経気管支肺生検で診断し得た軟骨肉腫肺転移の一例. 気管支学. 2022. 44. Suppl. S290-S290
鶴薗健太郎, 冨岡勇也, 大脇一人, 谷川健悟, 美園俊祐, 近藤清貴, 内田章文, 末次隆行, 水野圭子, 井上博雅. 当院の進行肺腺癌症例におけるTTF-1発現とペメトレキセド(PEM)の治療反応性の検討. 日本呼吸器学会誌. 2022. 11. 増刊. 174-174
米未紀子, 安田俊介, 里村緑, 谷川健悟, 美園俊祐, 内田章文, 三山英夫, 末次隆行, 水野圭子, 井上博雅. 当院で経験した胸腺癌症例の検討. 日本呼吸器学会誌. 2022. 11. 増刊. 279-279
大庭優士, 安田俊介, 鶴薗健太郎, 冨岡勇也, 松山崇弘, 三山英夫, 末次隆行, 水野圭子, 井上博雅, 田畑和宏, et al. イピリムマブ+ニボルマブ+カルボプラチン+ペメトレキセド併用療法で視力の改善が得られた脈絡膜転移を有する肺腺癌の1例. 肺癌. 2022. 62. 2. 141-141

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Education (1)：

Work history (1)：

2022/03 - 現在 KAGOSHIMA UNIVERSITY Graduate School of Medical and Dental Sciences Pulmonary medicine Specially Appointed Associate Professor

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