Rchr
J-GLOBAL ID:202201019331662694
Update date: Apr. 17, 2024
Ohtsuka Masayuki
Ohtsuka Masayuki
Affiliation and department:
Research field (1):
Digestive surgery
Research theme for competitive and other funds (47):
- 2023 - 2026 Functional analysis of BAP1 in the control of gastrointestinal cancer progression and metastasis.
- 2023 - 2026 大腸癌肝転移のTWEAK/Fn14 axisを介した腫瘍進展メカニズムの解明と新規治療薬の開発
- 2023 - 2026 肝内胆管癌病態形成におけるメカノトランスダクションの役割
- 2023 - 2026 ポリコームタンパクYAF2による大腸癌の進展、転移、再発における制御機構の解明
- 2023 - 2026 C5-C5aR1/2 axisを標的とした膵癌進展機構の解明と新規補体免疫賦活化療法への応用
- 2022 - 2025 Molecular mechanism of biliary tract carcinomas arising from patients with pancreaticobiliary malfunction
- 2022 - 2025 in vivoエストロゲン非依存性乳癌細胞株による内分泌療法抵抗性機序の解析研究
- 2022 - 2025 大腸癌におけるRYBP を介した腫瘍制御機構の解明
- 2021 - 2024 二重機能を有する抗酸化物質による難治性乳癌に対する新たな治療戦略
- 2021 - 2024 肝胆膵領域癌におけるIRG1を介した抗炎症作用に基づく新規治療戦略
- 2020 - 2023 膵癌進展進展機構に関わるC4BPA-CD40 axisの機能解析および治療開発
- 2020 - 2023 肝胆膵領域癌におけるLGR5を標的としたSTAT3活性抑制による新規治療の開発
- 2020 - 2023 内臓脂肪による免疫老化と慢性炎症が手術侵襲に及ぼす影響とオステオポンチンの関与
- 2020 - 2023 NETsを介した膵臓癌EMT-MET plasticity機構の解明
- 2019 - 2022 Mechanism of cancer progression mediated by IL-32-Gankyrin axis in intrahepatic cholangiocarcinoma
- 2019 - 2022 Tumor-suppressive role of Smad ubiquitination regulatory factor 2 in patients with colorectal cancer
- 2019 - 2022 Plasticity of cancer-initiating and cancer cells in intrahepatic cholangiocarcinoma and regulation of the cancer stromal microenvironment
- 2019 - 2022 The elucidation of mechanism underlying pancreatic cancer progression by complement and secreted proteins in tumor microenvironment.
- 2018 - 2021 Development of precision medicine for pancreatic cancer combining near infrared imaging and biological information
- 2018 - 2021 Antibody therapy using gene-transduced adipocytes for breast cancer
- 2017 - 2020 A new approach for avoiding age-related risks after extended hepatectomy by targeting Pin1.
- 2017 - 2020 Identification of biomarkers for biliary tract cancer by proteomic approaches
- 2016 - 2019 Role of YAP/TAZ in induction of cancer-initiating cells in cholangiocarcinoma and development of new targeting therapy
- 2015 - 2018 New criteria of pancreatic neuroendocrine tumors depending on expression levels of transcription factors related to neural and endocrine cell development
- 2014 - 2017 Identification of novel biomarkers for pancreato-biliary cancer by comprehensive protein profiling analysis
- 2013 - 2016 The kinetics and modulation of tumor-initiating cells regulated by cell differentiation and dedifferentiation in de novo primary liver cancer
- 2012 - 2015 Identification of pancreatic cancer stem cells and its interaction with surrouding stroma
- 2012 - 2015 Evaluation of the inhibited hepatic sinusoidal regeneration after hepatectomy in cirrhotic liver and attempt for promoting liver regeneration using endothelial progenitor cells
- 2011 - 2013 The strategy for reducing surgical risk by immunonutrition after severely stressful surgery
- 2012 - 2012 遺伝子発現、遺伝子多型からみた肝胆道領域高度侵襲手術後の感染制御の研究
- 2010 - 2012 Clinical heterogeneity brought about by tumor-initiating cells in primary liver cancer and the development of new therapeutic strategy by regulating microRNAs.
- 2009 - 2011 Evaluation of the signal transduction that controls hepatic sinusoidal regeneration and attempt to promote liver regeneration using endothelial progenitor cells.
- 2009 - 2010 生体肝移植および肝切除の適応拡大のための過大肝再生誘導について
- 2008 - 2010 Promotion of Liver Regeneration and Control of Infectious Complications after Liver Transplantation and Major Hepatectomy.
- 2007 - 2008 MicroRNAs and their potential for cancer development inhepatocellular and cholangiocellular carcinomas derived fromhepatic progenitor cells.
- 2007 - 2008 Antitumor effects and promotion of liver regeneration by controlling angiogenetic signal transduction
- 2007 - 2008 Mechanismsoftheinteractionbetweencancercells andmesenchymal Cells in gastroirltestinal cancer.
- 2006 - 2007 Regulation of organ dysfunction and infectious complications after liver transplantation : in the view of innate immunity and the Kupffer cells
- 2006 - 2007 A Novel Gene Therapy with Bone Marrow Stem Cell Homing
- 2005 - 2006 Mechanism of sinusoidal endothelial cell proliferation and maturation during hepatic regeneration
- 2005 - 2006 Early detection of postoperative sepsis and organ dysfunction using cDNA micro-array and therapeutic strategy for these complications by anti-TLR antibody.
- 2004 - 2005 Identification of factors involving chemotherapy resistance in pancreatic cancer patients by Protein Chip system for developing prediction system of chemotherapy response.
- 2004 - 2005 Inhibition of tumor angiogenesis through chondromodulin-I gene transfer
- 2003 - 2004 生体侵襲時の臓器不全発症過程におけるTLR-4およびMD-2蛋白の関与
- 2003 - 2004 Evaluation of Underlying Hepatic Status in Hepatocellular Carcinoma Recurrence by Oxidative Stress Markers for DNA Damage
- 2002 - 2003 Modification of donor MHC antigens with ribozyme RNA transfer to prevent rejection of graft liver
- 2001 - 2002 Cytochrome P450 and Cyclooxygenease-2 expression in liver tissue surrounding hepatocellur carcinoma : Evaluation of environmental state of multicentric hepatocarcinogenesis
Show all
Papers (517):
-
Yoshiki Shinomiya, Yusuke Kouchi, Sakurako Harada-Kagitani, Takayuki Ishige, Shigetsugu Takano, Masayuki Ohtsuka, Jun-Ichiro Ikeda, Takashi Kishimoto. ECM1 and KRT6A are involved in tumor progression and chemoresistance in the effect of dexamethasone on pancreatic cancer. Cancer science. 2024
-
Yoshifumi Miura, Hiroshi Ohyama, Rintaro Mikata, Yosuke Hirotsu, Kenji Amemiya, Hitoshi Mochizuki, Junichiro Ikeda, Masayuki Ohtsuka, Naoya Kato, Masao Omata. The efficacy of bile liquid biopsy in the diagnosis and treatment of biliary tract cancer. Journal of hepato-biliary-pancreatic sciences. 2024
-
Motoyasu Kan, Yusuke Kouchi, Hiroshi Ohyama, Genki Usui, Masaki Fukuyo, Shigetsugu Takano, Takashi Kishimoto, Atsushi Kaneda, Masayuki Ohtsuka, Naoya Kato. Genomic Analysis of Undifferentiated Carcinoma of the Pancreas with Squamous Differentiation: A Case Report. Cureus. 2024. 16. 2. e55175
-
Takashi Mishima, Shigetsugu Takano, Tsukasa Takayashiki, Satoshi Kuboki, Daisuke Suzuki, Nozomu Sakai, Isamu Hosokawa, Takanori Konishi, Hitoe Nishino, Shinichiro Nakada, et al. Serum elastase-1 predicts malignancy in intraductal papillary mucinous neoplasm of the pancreas. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 2023
-
粕谷 雅晴, 榊原 淳太, 山田 英幸, 山本 寛人, 吉村 悟志, 山崎 美智子, 高田 護, 藤本 浩司, 長嶋 健, 大塚 将之, et al. 乳癌皮下転移再発巣の針生検に造影超音波検査が有用であった1例. 乳腺甲状腺超音波医学. 2023. 12. 4. 131-131
more...
MISC (513):
-
菅元泰, 菅元泰, 大野泉, 大野泉, 關根優, 山田奈々, 遠山翔大, 杉原地平, 大内麻愉, 永嶌裕樹, et al. 高齢者膵癌に対するnal-IRI+5-FU/LV療法の安全性と抗腫瘍効果の検討. 膵臓(Web). 2023. 38. 3
-
高橋知也, 飯野陽太郎, 關根優, 山田奈々, 遠山翔大, 杉原地平, 大内麻愉, 菅元泰, 永嶌裕樹, 高橋幸治, et al. 術前診断に至らなかった膵管内進展をきたした膵神経内分泌腫瘍の1例. 膵臓(Web). 2023. 38. 3
-
大野 泉, 山田 俊儒, 對田 尚, 中川 良, 杉原 地平, 大内 麻愉, 菅 元泰, 丸田 四季子, 三浦 義史, 永嶌 裕樹, et al. 膵癌診療における真菌叢解析の可能性. 日本消化器病学会雑誌. 2022. 119. 臨増大会. A784-A784
-
榊原 淳太, 高屋敷 吏, 長嶋 健, 藤本 浩司, 髙田 護, 山田 英幸, 山本 寛人, 那須 克宏, 鈴木 ティベリュウ・浩志, 橋本 秀行, et al. 乳がん診療におけるCTとUS画像のフュージョンテクニック : 基本から応用まで-乳房超音波fusion技術のHow to and Pearls : JABTS 47/FUSION 02研究会企画. 乳腺甲状腺超音波医学 = Journal of breast and thyroid sonology / 日本乳腺甲状腺超音波医学会編集委員会 編. 2022. 11. 3. 35-39
-
神崎 洋彰, 千葉 哲博, 興梠 慧輔, 日下部 裕子, 小林 和史, 叶川 直哉, 清野 宗一郎, 中村 昌人, 近藤 孝行, 齊藤 朋子, et al. RNA結合蛋白ELAVL1のB型肝炎ウイルス複製と肝細胞癌増殖への関わり. 肝臓. 2022. 63. Suppl.1. A335-A335
more...
Professional career (1):
- Doctorate of Medical Science (Chiba University)
Return to Previous Page