Nagae Genta

Nagae Genta | Nagae Genta

Affiliation and department：
Job title： Project Associate Professor
Homepage URL (2)： https://www.rcast.u-tokyo.ac.jp/ja/research/people/staff-nagae_genta.html , https://www.rcast.u-tokyo.ac.jp/en/research/people/staff-nagae_genta.html

Research field (4)： Genomics , Gastroenterology , Systems genomics , Tumor biology

Research theme for competitive and other funds (7)：

2021 - 2025 Comprehensive analysis of dysregulated RNA modifications in liver cancer
2018 - 2021 Cellular deconvolution analysis of hepatocellular carcinoma based on the systemic epigenomic profiles
2017 - 2020 The elucidation of the mechanism of the development and progression of gliomas due to epigenetic deregulation and the identification of therapeutic targets
2015 - 2020 4D Chromosome structural information during differentiation
2015 - 2019 Epigenomic analysis of stem cell characteristics defining therapeutic resistance of liver cancer

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Papers (67)：

Sina Neyazi, Erika Yamazawa, Karoline Hack, Shota Tanaka, Genta Nagae, Catena Kresbach, Takayoshi Umeda, Alicia Eckhardt, Kenji Tatsuno, Lara Pohl, et al. Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation. Acta Neuropathologica. 2024. 147. 1
Amélie Roehrig, Theo Hirsch, Aurore Pire, Guillaume Morcrette, Barkha Gupta, Charles Marcaillou, Sandrine Imbeaud, Christophe Chardot, Emmanuel Gonzales, Emmanuel Jacquemin, et al. Single-cell multiomics reveals the interplay of clonal evolution and cellular plasticity in hepatoblastoma. Nature Communications. 2024
Aurore Pire, Theo Z. Hirsch, Guillaume Morcrette, Sandrine Imbeaud, Barkha Gupta, Jill Pilet, Marianna Cornet, Monique Fabre, Catherine Guettier, Sophie Branchereau, et al. Mutational signature, cancer driver genes mutations and transcriptomic subgroups predict hepatoblastoma survival. European Journal of Cancer. 2024
Kunihiko Morihiro, Shunto Morita, Naoki Harada, Manami Baba, Jongmin Yum, Mitsuru Naito, Kanjiro Miyata, Genta Nagae, Akimitsu Okamoto. RNA Oncological Therapeutics: Intracellular Hairpin RNA Assembly Enables MicroRNA-Triggered Anticancer Functionality. Journal of the American Chemical Society. 2024. 146. 2. 1346-1355
Taijun Hana, Akitake Mukasa, Masashi Nomura, Genta Nagae, Shogo Yamamoto, Kenji Tatsuno, Hiroki Ueda, Shiro Fukuda, Takayoshi Umeda, Shota Tanaka, et al. Region-specific DNA hydroxymethylation along the malignant progression of IDH-mutant gliomas. Cancer Science. 2024

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MISC (21)：

柴田龍弘. がんゲノムペディア -77のキーワードで理解するゲノム医療とゲノム研究. 2024. 104-107
永江玄太. 総論:疾患の病態解明に向けた統合オミックス解析. 遺伝子医学統合オミックス解析. 2023. 13. 3
永江玄太. 小児肝芽腫発症に関与する分化制御因子. 生化学. 2022. 94. 3. 438-442
永江玄太. 【がんゲノム医療時代の分子腫瘍学】(第1部)がんの分子病理学(序論) 解析法ヒトゲノム研究におけるマイクロアレイ解析(CGH・SNP・メチル化など). 病理と臨床. 2022. 40. 臨増. 057-063
永江玄太. 泌尿器科領域におけるシングルセル解析の可能性. 泌尿器科. 2022. 15. 4. 465-471

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Education (2)：

- 2008 The University of Tokyo Graduate School of Medicine
- 2000 The University of Tokyo Faculty of Medicine School of Medicine

Professional career (2)：

M.D. (The University of Tokyo)
Ph.D. (The University of Tokyo)

Work history (10)：

2021/04 - 現在 The University of Tokyo Research Center for Advanced Science and Technology Project Associate Professor
2017/07 - 2021/03 The University of Tokyo Research Center for Advanced Science and Technology Lecturer
2018/04 - 2019/03 University of Cambridge Clare Hall College Visiting Fellow
2018/04 - 2019/03 Wellcome Sanger Institute Visiting Scientist
2015/10 - 2017/06 The University of Tokyo Research Center for Advanced Science and Technology Project Lecturer

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Committee career (1)：

2022/01 - 現在日本癌学会評議員

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