OIKE NAOKI

オオイケナオキ | OIKE NAOKI

Affiliation and department：
Job title： Assistant professor
Research theme for competitive and other funds (3)：

2024 - 2027 Novel immunotherapy for Ewing like sarcoma
2024 - 2027 がん骨転移と筋委縮に対する抗スクレロスチン抗体療法
2022 - 2024 Development of novel NK cell therapy for soft tissue sarcoma

Papers (25)：

Nobuhiro Kubo, Minori Baba, Chansu Shin, Yasushi Kasahara, Ryosuke Hosokai, Yudai Murayama, Naoki Oike, Keichiro Mihara, Akihiko Saitoh, Masaru Imamura, et al. A novel method for generating chimeric antigen receptor-transduced primary human natural killer cells by the use of multiple cytokines and anti-CD2 and anti-NKp46 stimulatory antibodies. Biomedicine & Pharmacotherapy. 2025
Andrew Goodspeed, Avery Bodlak, Alexis B Duffy, Sarah Nelson-Taylor, Naoki Oike, Timothy Porfilio, Ryota Shirai, Deandra Walker, Amy Treece, Jennifer Black, et al. Single cell RNA-sequencing of Ewing sarcoma tumors demonstrates transcriptional heterogeneity and clonal evolution. Clinical cancer research : an official journal of the American Association for Cancer Research. 2025
Andrew Goodspeed, Avery Bodlak, Alexis B Duffy, Sarah Nelson-Taylor, Naoki Oike, Timothy Porfilio, Ryota Shirai, Deandra Walker, Amy Treece, Jennifer Black, et al. Characterization of transcriptional heterogeneity and novel therapeutic targets using single cell RNA-sequencing of primary and circulating Ewing sarcoma cells. bioRxiv : the preprint server for biology. 2024
Osamu Ansai, Ryota Hayashi, Anna Nakamura, Jin Sasaki, Akito Hasegawa, Tokiko Deguchi, Akihiko Yuki, Naoki Oike, Takashi Ariizumi, Masahiro Abe, et al. Deep dermatophytosis caused by Trichophyton rubrum in an elderly patient with CARD9 deficiency: A case report and literature review. The Journal of dermatology. 2024. 51. 2. 294-300
Ryota Shirai, Tyler Biebighauser, Deandra Walker, Jillian Oviedo, Sarah Nelson-Taylor, Avery Bodlak, Timothy Porfilio, Naoki Oike, Andrew Goodspeed, Masanori Hayashi. Cadherin-11 contributes to the heterogenous and dynamic Wnt-Wnt-β-catenin pathway activation in Ewing sarcoma. PloS one. 2024. 19. 6. e0305490

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MISC (38)：

富山泰行, 目良恒, 目良恒, 大池直樹, 野中秀紀, 上野惟, 大橋瑠子, 土屋淳紀, 谷藤理, 望月友晴, et al. Localization of human Adipose tissue-derived mesenchymal stem cells injected intra-articularly for rat cartilage defect repair. 日本軟骨代謝学会プログラム・抄録集. 2020. 33rd. 8. S1822-S1822
川島寛之, 有泉高志, 山岸哲郎, 大池直樹, 遠藤直人, 生越章, 畠野宏史, 佐々木太郎. 軟部肉腫患者に対する新規抗がん剤治療による予後の変化. 日本整形外科学会雑誌. 2019. 93. 6. S1396-S1396
生越章, 川島寛之, 有泉高志, 山岸哲郎, 大池直樹, 遠藤直人. 脂肪腫と異型脂肪腫様腫瘍の自然史の解析. 日本整形外科学会雑誌. 2019. 93. 6. S1469-S1469
有泉高志, 川島寛之, 山岸哲郎, 大池直樹, 遠藤直人, 生越章. 骨・軟部腫瘍に対する穿刺吸引細胞診ならびに針生検の正確性の検討. 日本整形外科学会雑誌. 2019. 93. 6. S1492-S1492
山岸哲郎, 川島寛之, 生越章, 有泉高志, 大池直樹, 佐々木太郎, 畠野宏史, 遠藤直人. 骨・軟部腫瘍の針生検検体による遺伝子診断の有用性. 日本整形外科学会雑誌. 2019. 93. 6. S1492-S1492

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Professional career (1)：

PH.D (Niigata University)

Awards (2)：

2022/06 - Yujin young Investigator Award
2019/12 - University of Colorado University of Colorado Postdoctoral Association Travelling Award High-throughput drug screening combined with a druggable target CRISPR drop-out screen identifies therapeutic vulnerabilities of BCOR-CCNB3 fusion positive sarcomas

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