HIRUNAGI Tomoki

ヒルナギトモキ | HIRUNAGI Tomoki

Affiliation and department：
Research theme for competitive and other funds (6)：

2024 - 2026 Development of next-generation antisense therapeutics for neurological diseases
2023 - 2026 Elucidation of temporal alteration in motor neuron-oligodendrocyte interaction in motor neuron diseases
2022 - 2025 Therapeutic development against protein aggregation
2022 - 2025 Development of neuronal aggregates-targeted therapeutics
2022 - 2024 運動ニューロン疾患の初期軸索病態の解明

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Papers (13)：

Tomoki Hirunagi, Hideaki Nakatsuji, Kentaro Sahashi, Mikiyasu Yamamoto, Madoka Iida, Genki Tohnai, Naohide Kondo, Shinichiro Yamada, Ayuka Murakami, Seiya Noda, et al. Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy. Journal of cachexia, sarcopenia and muscle. 2023
Mayumi Kataoka, Kentaro Sahashi, Koyo Tsujikawa, Jun-Ichi Takeda, Tomoki Hirunagi, Madoka Iida, Masahisa Katsuno. Dysregulation of Aldh1a2 underlies motor neuron degeneration in spinal muscular atrophy. Neuroscience research. 2023
Kensuke Daida, Shotaro Shimonaka, Kahori Shiba-Fukushima, Jun Ogata, Hiroyo Yoshino, Ayami Okuzumi, Taku Hatano, Yumiko Motoi, Tomoki Hirunagi, Masahisa Katsuno, et al. α-Synuclein V15A Variant in Familial Parkinson's Disease Exhibits a Weaker Lipid-Binding Property. Movement disorders : official journal of the Movement Disorder Society. 2022. 37. 10. 2075-2085
Yosuke Ogura, Kentaro Sahashi, Tomoki Hirunagi, Madoka Iida, Takaki Miyata, Masahisa Katsuno. Mid1 is associated with androgen-dependent axonal vulnerability of motor neurons in spinal and bulbar muscular atrophy. Cell death & disease. 2022. 13. 7. 601-601
Tomoki Hirunagi, Kentaro Sahashi, Katherine G Meilleur, Masahisa Katsuno. Nucleic Acid-Based Therapeutic Approach for Spinal and Bulbar Muscular Atrophy and Related Neurological Disorders. Genes. 2022. 13. 1

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MISC (4)：

蛭薙智紀, 勝野雅央. 【骨格筋のすべて-メカニズムからサルコペニアまで】筋症状を伴う疾患球脊髄性筋萎縮症. Clinical Neuroscience. 2023. 41. 2. 260-262
橋詰淳, 佐橋健太郎, 蛭薙智紀, 勝野雅央. 【神経疾患とゲノム医療】個別病態・疾患のゲノム医療球脊髄性筋萎縮症. Clinical Neuroscience. 2022. 40. 9. 1143-1146
山田晋一郎, 蛭薙智紀, 佐橋健太郎, 勝野雅央. 球脊髄性筋萎縮症と脊髄性筋萎縮症-Spinal and bulbar muscular atrophy (SBMA) and bulbar muscular atrophy (SMA)-特集神経疾患における遺伝医療の進歩. 日本内科学会雑誌. 2022. 111. 8. 1532-1540
Hirunagi Tomoki, Murao Atsunori, Goto Yoji, Mano Kazuo. Reversible cerebral vasoconstriction syndrome occurring after surgery for uterine cancer with severe anemia: a case report. Japanese Journal of Stroke. 2017. 39. 3. 190-194

Patents (1)：

Professional career (1)：

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