Yagi Mikako

ヤギミカコ | Yagi Mikako

Affiliation and department：
Research theme for competitive and other funds (7)：

2022 - 2025 ミトコンドリア機能異常による老化疾患の分子病態の解明とNMNによる治療効果
2021 - 2023 老化に伴い発症するミトコンドリア関連性疾患の機能解析と予防治療
2020 - 2020 ミトコンドリア翻訳障害によりNAD+が減少しリソソーム機能低下を引き起こす
2018 - 2020 Search for new mechanisms by which mitochondria control autophagy and metabolites of aging-related diseases
2019 - 2019 ミトコンドリア翻訳機能低下はNAD合成を介してリソソーム機能を制御する

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Papers (31)：

Saori Ueda, Mikako Yagi, Ena Tomoda, Shinya Matsumoto, Yasushi Ueyanagi, Yura Do, Daiki Setoyama, Yuichi Matsushima, Asuteka Nagao, Tsutomu Suzuki, et al. Mitochondrial haplotype mutation alleviates respiratory defect of MELAS by restoring taurine modification in tRNA with 3243A > G mutation. Nucleic acids research. 2023. 51. 14. 7480-7495
Kenji Miki, Mikako Yagi, Naoki Noguchi, Yura Do, Ryosuke Otsuji, Daisuke Kuga, Dongchon Kang, Koji Yoshimoto & Takeshi Uchiumi. Induction of glioblastoma cell ferroptosis using combined treatment with chloramphenicol and 2-deoxy-d-glucose. Scientific Reports. 2023
Shun Fujinuma, Hirokazu Nakatsumi, Hideyuki Shimizu, Shigeaki Sugiyama, Akihito Harada, Takeshi Goya, Masatake Tanaka, Motoyuki Kohjima, Masatomo Takahashi, Yoshihiro Izumi, et al. FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation. Cell Reports. 2023
Kenji Miki, Mikako Yagi, Koji Yoshimoto, Dongchon Kang, Takeshi Uchiumi. Mitochondrial dysfunction and impaired growth of glioblastoma cell lines caused by antimicrobial agents inducing ferroptosis under glucose starvation. ONCOGENESIS. 2022. 11. 1
Masakazu Fujii, Daiki Setoyama, Kazuhito Gotoh, Yushi Dozono, Mikako Yagi, Masataka Ikeda, Tomomi Ide, Takeshi Uchiumi, Dongchon Kang. TFAM expression in brown adipocytes confers obesity resistance by secreting extracellular vesicles that promote self-activation. ISCIENCE. 2022. 25. 9

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Books (3)：

Lectures and oral presentations (5)：

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