Rchr
J-GLOBAL ID：202301009278179520
Update date: Apr. 17, 2024
Isono Mayu
イソノ マユ | Isono Mayu
Affiliation and department：
Job title：
Researcher
Research field (1)：
Molecular biology
Research keywords (12)：
DNA修復
, 放射線影響
, 炎症・免疫応答
, 遺伝子発現解析
, 次世代シーケンス解析
, バイオインフォマティクス解析
, DSB修復
, DSB修復経路選択性
, HR
, NHEJ
, 53BP1
, BRCA1
Research theme for competitive and other funds (5)：
- 2020 - 2023 RNAポリメラーゼIIのDNA二本鎖切断修復機構への関与の解明
- 2017 - 2020 Regulation of 53BP1 repositioning and foci formation during homologous recombination
- 2015 - 2017 Visualization of heavy-ion induced clustered DNA double strand break formation using super-resolution microscopy
- 2013 - 2015 The measurement of cell death in human neural stem cells and glioblastoma cells
- 2010 - 2012 マイクロビーム照射法を用いた神経幹細胞の増殖・分化に関する放射線の影響
Papers (14)：
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Yuka Nakazawa, Yuichiro Hara, Yasuyoshi Oka, Okiru Komine, Diana van den Heuvel, Chaowan Guo, Yasukazu Daigaku, Mayu Isono, Yuxi He, Mayuko Shimada, et al. Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair. Cell. 2020. 180. 6. 1228-1244
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Mayu Isono, Satoru Hashimoto. DNA Fragment Agarose Gel Electrophoresis for Chromatin Immunoprecipitation (ChIP). Methods in molecular biology (Clifton, N.J.). 2020. 2119. 201-211
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Yoshihiko Hagiwara, Atsuko Niimi, Mayu Isono, Motohiro Yamauchi, Takaaki Yasuhara, Siripan Limsirichaikul, Takahiro Oike, Hiro Sato, Kathryn D Held, Takashi Nakano, et al. 3D-structured illumination microscopy reveals clustered DNA double-strand break formation in widespread γH2AX foci after high LET heavy-ion particle radiation. Oncotarget. 2017. 8. 65. 109370-109381
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Hiro Sato, Atsuko Niimi, Takaaki Yasuhara, Tiara Bunga Mayang Permata, Yoshihiko Hagiwara, Mayu Isono, Endang Nuryadi, Ryota Sekine, Takahiro Oike, Sangeeta Kakoti, et al. DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells. Nature communications. 2017. 8. 1. 1751-1751
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Ryo Sakasai, Mayu Isono, Mitsuo Wakasugi, Mitsumasa Hashimoto, Yumi Sunatani, Tadashi Matsui, Atsushi Shibata, Tsukasa Matsunaga, Kuniyoshi Iwabuchi. Aquarius is required for proper CtIP expression and homologous recombination repair. Scientific reports. 2017. 7. 1. 13808-13808
ｍore...
Education (3)：
- 2010 - 首都大学東京人間健康科学研究科 後期博士課程
- 2008 - 首都大学東京人間健康科学研究科 前期博士課程
- 2004 - 東京都立保健科学大学保健科学部放射線学科
Professional career (1)：
- 博士(放射線学) (首都大学東京人間健康科学研究科)
Work history (6)：
Association Membership(s) (1)：
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