Shimizu Takashi

Research keywords (2)：小胞体ストレス , がん免疫

Research theme for competitive and other funds (2)：

2020 - 2022 遺伝性肺動脈性肺高血圧症の新規治療薬の開発
2018 - 2020 Analysis for biomarkers derived from placenta in postpartum cardiomyopathy with preeclampsia

Papers (10)：

Tsubasa Goshima, Katsuaki Ieguchi, Nobuyuki Onishi, Takashi Shimizu, Daisuke Takayanagi, Makoto Watanabe, Yuki Fujimoto, Ryotaro Ohkuma, Risako Suzuki, Toshiaki Tsurui, et al. Non-classical Monocytes Enhance the Efficacy of Immune Checkpoint Inhibitors on Colon Cancer in a Syngeneic Mouse Model. Anticancer research. 2024. 44. 1. 23-29
Takashi Shimizu, Eisuke Inoue, Ryotaro Ohkuma, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada. Soluble PD-L1 changes in advanced non-small cell lung cancer patients treated with PD-1 inhibitors: an individual patient data meta-analysis. Frontiers in immunology. 2023. 14. 1308381-1308381
Ryotaro Ohkuma, Sakiko Miura, Satoshi Muto, Yoshitaka Toyomasu, Yuki Fujimoto, Katsuaki Ieguchi, Nobuyuki Onishi, Takashi Shimizu, Makoto Watanabe, Daisuke Takayanagi, et al. Novel quantitative immunohistochemical analysis for evaluating PD-L1 expression with phosphor-integrated dots for predicting the efficacy of patients with cancer treated with immune checkpoint inhibitors. Frontiers in immunology. 2023. 14. 1260492-1260492
Tomotaka Ugai, Takashi Shimizu, Hidetaka Kawamura, Satoko Ugai, Yasutoshi Takashima, Genki Usui, Juha P Väyrynen, Kazuo Okadome, Koichiro Haruki, Naohiko Akimoto, et al. Inverse relationship between Fusobacterium nucleatum amount and tumor CD274 (PD-L1) expression in colorectal carcinoma. Clinical & translational immunology. 2023. 12. 8. e1453
Takashi Shimizu, Akashi Taguchi, Yoshiki Higashijima, Yasuharu Kanki, Ryo Nakaki, Yoshihiro Urade, Youichiro Wada. Inhibition of cardiac PERK signaling promotes peripartum cardiac dysfunction. Scientific Reports. 2021. 11. 1

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Education (2)：

2012 - 2016 The University of Tokyo
2002 - 2008 The University of Tokyo Faculty of Medicine School of Medicine

Work history (6)：

2023/04 - 現在 Showa University
2019/04 - 2023/03 The University of Tokyo Isotope Science Center
2021/06 - 2023/01 Brigham and women's hospital
2016/04 - 2019/03 The University of Tokyo Faculty of Medicine University Hospital Cardiovascular Medicine
2010/04 - 2012/03 榊原記念病院循環器内科専修医

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Awards (1)：

2022/01 - 公益信託循環器学研究振興基金循環器学研究振興基金賞(内田賞)

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