Rchr
J-GLOBAL ID:202301011125235727
Update date: Sep. 29, 2024
Miyata Kenichi
ミヤタ ケンイチ | Miyata Kenichi
Affiliation and department:
Research keywords (10):
適応
, Epigenetic Adaptation
, EpiModifier
, Cellular barcoding
, ゲノム編集
, がん多様性
, リピート領域
, 細胞老化
, 老化細胞分泌因子
, がん転移
Research theme for competitive and other funds (12):
- 2024 - 2027 腫瘍内不均一性の形成過程における染色体外DNAの果たす役割の解明
- 2023 - 2026 エピゲノム異常がもたらすがん細胞の多様性及び治療抵抗性獲得機構の解析
- 2023 - 2025 リピート領域も包括したオミクス解析法による新たな細胞の特徴と機能の解明
- 2020 - 2023 乳がん細胞における老化様エピゲノム異常がもたらす悪性化機構の解明
- 2019 - 2022 細胞老化特異的なノンコーディングRNAによる腫瘍発症メカニズムの解析
- 2018 - 2020 The analysis of tumor cells showing the senescence-like gene expression profile
- 2016 - 2019 Elucidation of transformation mechanism from benign tumor to cancer
- 2016 - 2018 In vivoスクリーニングによるがん転移制御分子の同定と機能解析
- 2015 - 2017 Functional analysis of Merm1 promoting tumor metastasis
- 2014 - 2016 Molecular analysis of platelet-mediated tumor suppression and development of the anti-tumor therapy
- 2012 - 2015 Molecular analysis of EGFR-TKI resistance and development of overcoming drugs
- 2010 - 2015 Molecular analysis of metastasis-related tumor microenvironment and development of new anti-metastatic therapy
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Papers (18):
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Takahiko Murayama, Jun Nakayama, Xinpei Jiang, Kenichi Miyata, Alexander D. Morris, Kathy Q. Cai, Rahul M. Prasad, Xueying Ma, Andrey Efimov, Neel Belani, et al. Targeting DHX9 Triggers Tumor-Intrinsic Interferon Response and Replication Stress in Small Cell Lung Cancer. Cancer Discovery. 2024
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Masatomo Chiba, Kenichi Miyata, Hikaru Okawa, Yoko Tanaka, Koji Ueda, Hiroyuki Seimiya, Akiko Takahashi. YBX1 Regulates Satellite II RNA Loading into Small Extracellular Vesicles and Promotes the Senescent Phenotype. International Journal of Molecular Sciences. 2023
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Kenichi Miyata, Xiangyu Zhou, Mika Nishio, Aki Hanyu, Masatomo Chiba, Hiroko Kawasaki, Tomo Osako, Kengo Takeuchi, Shinji Ohno, Takayuki Ueno, et al. Chromatin conformational changes at human satellite II contribute to the senescence phenotype in the tumor microenvironment. Proceedings of the National Academy of Sciences. 2023
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Kohei Kumegawa, Liying Yang, Kenichi Miyata, Reo Maruyama. FOXD1 is associated with poor outcome and maintains tumor-promoting enhancer-gene programs in basal-like breast cancer. Frontiers in Oncology. 2023. 13
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Sumito Saeki, Kohei Kumegawa, Yoko Takahashi, Liying Yang, Tomo Osako, Mahmut Yasen, Kazutaka Otsuji, Kenichi Miyata, Kaoru Yamakawa, Jun Suzuka, et al. Transcriptomic intratumor heterogeneity of breast cancer patient-derived organoids may reflect the unique biological features of the tumor of origin. Breast Cancer Research. 2023. 25. 1
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Work history (5):
- 2022/04 - 現在 Japanese Foundation for Cancer Research
- 2021/08 - 現在 Japanese Foundation for Cancer Research
- 2019/04 - 2022/03 日本学術振興会特別研究員(PD)
- 2017/04 - 2021/03 Japanese Foundation for Cancer Research
- 2016/04 - 2018/03 日本学術振興会特別研究員(DC2)
Awards (1):
Association Membership(s) (2):
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