Rchr
J-GLOBAL ID：202301013224719500
Update date: Nov. 20, 2023
Okamoto Akiko
オカモト アキコ | Okamoto Akiko
Affiliation and department：
Research theme for competitive and other funds (5)：
- 2021 - 2024 CCT2複合ヘテロ変異による網膜変性モデルマウスの病態と網羅的タンパク質定量解析
- 2018 - 2023 in vivo and in vitro analysis of LRRTM4 mutation associated with dominant-inherited macular degeneration.
- 2015 - 2018 Induction of Muller glia-derived retinal regeneration by expressing regeneration promoting genes
- 2010 - 2012 Screening and functional screening of the genes which regulate the proliferation of Muller glia in damaged retina.
- 2007 - 2009 LIM-homeobox transcription factors regulate neuronal dendritic morphogenesis in subtype-specific manner.
Papers (12)：
-
Pan Y, Suga A, Kimura I, Kimura C, Minegishi Y, Nakayama M, Yoshitake K, Iejima D, Minematsu N, Yamamoto M, et al. METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma. The Journal of clinical investigation. 2022
-
Suga A, Yoshitake K, Minematsu N, Tsunoda K, Kaoru Fujinami, Miyake Y, Kuniyoshi K, Hayashi T, Mizobuchi K, Ueno S, et al. Genetic characterization of 1210 Japanese pedigrees with inherited retinal diseases by whole-exome sequencing. Human mutation. 2022
-
Yang Pan, Daisuke Iejima, Mao Nakayama, Akiko Suga, Toru Noda, Inderjeet Kaur, Taraprasad Das, Subhabrata Chakrabarti, Robyn H. Guymer, Margaret M. DeAngelis, et al. Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro. Journal of Biological Chemistry. 2021. 296. 100456-100456
-
Huiping Li, Shiqin Yuan, Yuriko Minegishi, Akiko Suga, Kazutoshi Yoshitake, Xunlun Sheng, Jianping Ye, Stuart Smith, Gabor Bunkoczi, Megumi Yamamoto, et al. Novel mutations in malonyl-CoA-acyl carrier protein transacylase provoke autosomal recessive optic neuropathy. Human Molecular Genetics. 2020. 29. 3. 444-458
-
Akiko Suga, Megumi Yamamoto, Takeshi Iwata. Gene editing of mouse Lrrtm4, a bipolar synaptic protein, responsible for macular dystrophy in human, shows photoreceptor degeneration by light stimulation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2019. 60. 9
ｍore...
MISC (1)：
-
Takeshi Iwata, Huiping Li, Yuan Shiqin, Yuriko Minegishi, Akiko Suga, Kazutoshi Yoshitake, Jianping Ye, Stuart Smith, Gabor Bunkoczi, Megumi Yamamoto, et al. Novel mutations in Malonyl-CoA-Acyl Carrier Protein Transacylase gene provoke autosomal recessive optic neuropathy. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2020. 61. 7
Professional career (1)：
Return to Previous Page
