Kasai Kosuke

カサイコウスケ | Kasai Kosuke

Affiliation and department：
Job title： Associate Professor

Research field (1)： Molecular biology

Research keywords (4)：タンパク質合成 , 抗菌物質探索 , L-アミノ酸オキシダーゼ , 抗菌タンパク質

Research theme for competitive and other funds (12)：

2022 - 2025 放射線誘発バイスタンダー効果の進化的保存性の検証
2021 - 2024 抗菌L-アミノ酸オキシダーゼの金属による複合体形成と活性調節機序の解明
2019 - 2023 放射線被ばくと糖尿病の二重ストレスの生体影響解析
2019 - 2022 Low-Dose radiation effects on freshwater planarian (Dugesia japonica), in Fukushima
2021 - 2021 ヒト化抗菌タンパク質を用いた皮膚炎症起因菌の増殖を抑える機能性バイオ化粧品の開発

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Papers (42)：

Ryo Nakayama, Donovan Anderson, Valerie Swee Ting Goh, Yohei Fujishima, Kaito Yanagidate, Kentaro Ariyoshi, Kosuke Kasai, Mitsuaki A Yoshida, William F Blakely, Tomisato Miura. Optimizing chemical-induced premature chromosome condensation assay for rapid estimation of high-radiation doses. Radiation Protection Dosimetry. 2024
Kimihiko Satoh, Daishi Yamakawa, Kosuke Kasai, Ichiro Hatayama. Vibratome technique revealed initial carcinogenic changes that induce GST-P+ single hepatocytes and minifoci in rat liver. Analytical biochemistry. 2023. 672. 115168-115168
Valerie Swee Ting Goh, Yohei Fujishima, Ryo Nakayama, Kai Takebayashi, Mitsuaki A Yoshida, Kosuke Kasai, Kentaro Ariyoshi, Tomisato Miura. Manual Scoring with Shortened 48 h Cytokinesis-Block Micronucleus Assay Feasible for Triage in the Event of a Mass-Casualty Radiation Accident. Radiation research. 2023. 199. 4. 385-395
Kentaro Ariyoshi, Yohei Fujishima, Valerie Swee Ting Goh, Akifumi Nakata, Kosuke Kasai, Mitsuaki A Yoshida, Tomisato Miura. Exosome-like vesicles released from ob/ob mouse adipose tissue enhance cell survival of cells with radiation-induced genomic instability. Journal of radiation research. 2023. 64. 2. 352-357
Kai Kudo, Takashi Kobayashi, Kosuke Kasai, Hiroyuki Nozaka, Toshiya Nakamura. Chondroitin sulfate is not digested at all in the mouse small intestine but may suppress interleukin 6 expression induced by tumor necrosis factor-α. Biochemical and biophysical research communications. 2023. 642. 185-191

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MISC (13)：

中山亮, 柳舘快利, Valerie Swee Ting Goh, 有吉健太郎, 葛西宏介, Blakely William F., 吉田光明, 三浦富智. 緊急被ばく医療における短縮化学誘導早期染色体凝縮法の従来法との比較(Comparison of shortened and conventional chemical-induced premature chromosome condensation methods in emergency radiation medicine). 日本放射線影響学会大会講演要旨集. 2022. 65回. 85-85
有吉健太郎, 藤嶋洋平, 葛西宏介, 三浦富智, 中田章史, 吉田光明. 染色体異数性を誘導した正常ヒト細胞におけるMyc過剰発現とゲノム不安定化への関与(Induction of Myc Overexpression and Genomic Instability in Artificial Human Aneuploid Cells). 日本放射線影響学会大会講演要旨集. 2022. 65回. 135-135
三浦富智, 伊東杏, 矢部優太, 藤嶋洋平, 金浜朱希, Goh Valerie, 越後谷直樹, 有吉健太郎, 葛西宏介, 中田章史, et al. 医療被ばく・作業被ばくがもたらす細胞遺伝的な影響と評価方法について医療被ばく及び職業被ばくにおける染色体異常解析(Cytogenetic effects of medical examination and medical worker exposures Chromosome aberration studies in medical and occupational exposures). 日本放射線影響学会大会講演要旨集. 2020. 63回. 5-5
中山亮, 柳舘快利, Goh Valerie Swee Ting, 有吉健太郎, 葛西宏介, Blakely William F., 吉田光明, 三浦富智. 生物学的線量評価における化学誘導早期染色体凝集法の短縮化(Development of shortened chemical premature chromosome condensation(PCC) assay in biodosimetry). 日本放射線影響学会大会講演要旨集. 2020. 63回. 95-95
藤嶋洋平, 中田章史, Goh Valerie, 葛西宏介, 有吉健太郎, 鈴樹亨純, 山城秀昭, 篠田壽, 鈴木正敏, 吉田光明, et al. 野生動物と実験動物を用いた放射線生物影響解明のための多元的アプローチ福島県の放射線汚染地域に生息する種々の野生動物における染色体解析(Pluralistic approach to elucidating radiobiological effects using wild and experimental animals Assessment of chromosome aberrations in wild animals in Fukushima). 日本放射線影響学会大会講演要旨集. 2020. 63回. 40-40

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Education (4)：

2007 - 2010 国立大学法人弘前大学大学院保健学研究科保健学専攻保健学専攻
2005 - 2007 国立大学法人弘前大学大学院医学系研究科保健学専攻
2001 - 2001 弘前大学農学部
1996 - 2001 弘前大学農学部生物資源科学科

Work history (4)：

2021/04 - 現在 Hirosaki University Graduate School of Health Sciences
2015/04 - 2021/03 Hirosaki University Graduate School of Health Sciences
2007/04 - 2015/03 Hirosaki University Graduate School of Health Sciences
2004/12 - 2007/03 Hirosaki University School of Medicine

Association Membership(s) (2)：

日本生化学会 , 日本分子生物学会

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