Rchr
J-GLOBAL ID：202301019874442233   Update date: Jun. 30, 2024

HIMENO MISAO

ヒメノ ミサオ | HIMENO MISAO
Affiliation and department：
The University of Tokyo, Graduate School of Medicine School of Internationa health, International Biomedical Sciences, Department of Developmental Medical Sciences

About The University of Tokyo, Graduate School of Medicine School of Internationa health, International Biomedical Sciences, Department of Developmental Medical Sciences


Job title： Assistant Professor
Research field  (2)： Developmental biology ,  Virology
Research keywords  (10)： 3D Co-Culture ,  host factors ,  Cancer ,  LINE-1 ,  HIV ,  induced Pluripotent Stem Cells ,  Hepatitis virus ,  Japanese encephalitis virus ,  ZIKA virus ,  Dengue virus
Research theme for competitive and other funds  (6)：
  • 2024 - 2027 Determination of T-B cell epitope for the development of novel anti-flavivirus therapeutic antibodies and contribution to a better understanding of pathogenesis
  • 2020 - 2023 B型肝炎ウイルス感染による線維化発症メカニズムの解明と新規治療標的の同定
  • 2020 - 2023 蛍光活性化タンパク質を用いたB型肝炎ウイルス検出系の構築とその応用
  • 2018 - 2022 Establishment of three dimensional HBV infection model which reflects the pathological progression
  • 2010 - 2012 C型肝炎ウイルス複製に関与する宿主因子の同定および機能解析
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Papers (21)：
  • Kazumi Haga, Zhenying Nancy Chen, Misao Himeno, Ryuichi Majima, Meng Ling Moi. Utility of an In-Vitro Micro-Neutralizing Test in Comparison to a Plaque Reduction Neutralization Test for Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Serology and Drug Screening. Pathogens (Basel, Switzerland). 2023. 13. 1
  • Misao Himeno, Shin-Wei Chen, Taketomo Kido. Co-culture Model for Hepatitis B Virus Infection Using iPSC-Derived Liver Progenitor Cells and Liver Sinusoidal Endothelial Cells. Methods in molecular biology (Clifton, N.J.). 2022. 2544. 107-117
  • Yuta Koui, Misao Himeno, Yusuke Mori, Yasuhiro Nakano, Eiko Saijou, Naoki Tanimizu, Yoshiko Kamiya, Hiroko Anzai, Natsuki Maeda, Luyao Wang, et al. Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling. Stem cell reports. 2021. 16. 12. 3050-3063
  • Shin-Wei Chen, Misao Himeno, Yuta Koui, Masaya Sugiyama, Hironori Nishitsuji, Masashi Mizokami, Kunitada Shimotohno, Atsushi Miyajima, Taketomo Kido. Modulation of hepatitis B virus infection by epidermal growth factor secreted from liver sinusoidal endothelial cells. Scientific reports. 2020. 10. 1. 14349-14349
  • Naoki Shigi, Masaki Horitani, Kenjyo Miyauchi, Tsutomu Suzuki, Misao Kuroki. An ancient type of MnmA protein is an iron-sulfur cluster-dependent sulfurtransferase for tRNA anticodons. RNA. 2020. 26. 3. 240-250
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MISC (6)：
  • 姫野 美沙緒, 木戸 丈友. 【肝類洞壁細胞研究における新知見】肝臓の発生、再生と類洞壁細胞 iPS細胞から肝類洞壁細胞への分化誘導法. 肝胆膵. 2021. 82. 4. 503-509
  • 鴫 直樹, 堀谷 正樹, 宮内 健常, 鈴木 勉, 姫野 美沙緒[黒木]. 酸素感受性[4Fe-4S]クラスターを有するtRNA硫黄化酵素MnmAの機能解析. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [1Z05-221)]
  • 黒木 美沙緒, 有海 康雄, 池田 正徳, 團迫 浩方, 脇田 隆字, 加藤 宣之. がん抑制因子PMLはHCV生活環に必須である(The PML tumor suppressor protein is required for HCV life cycle). 日本癌学会総会記事. 2010. 69回. 91-91
  • Ariumi Yasuo, Kuroki Misao, Dansako Hiromichi, Abe Kenichi, Ikeda Masanori, Wakita Takaji, Kato Nobuyuki. The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication. Okayama Igakkai Zasshi (Journal of Okayama Medical Association). 2010. 122. 1. 9-16
  • 有海 康雄, 黒木 美沙緒, 團迫 浩方, 阿部 健一, 池田 正徳, 脇田 隆字, 加藤 宣之. ATM DNA損傷センサーはC型肝炎ウイルスのRNA複製に必要である(ATM, a DNA damage sensor, is required for hepatitis C virus RNA replication). 日本癌学会総会記事. 2008. 67回. 482-483
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