Rchr
J-GLOBAL ID:202401000023575545   Update date: Mar. 25, 2024

Sarai Naoyuki

サライ ナオユキ | Sarai Naoyuki
Affiliation and department:
Job title: Specially Appointed Associate Professor
Research field  (5): Virology ,  Cell biology ,  Molecular biology ,  Structural biochemistry ,  Functional biochemistry
Research keywords  (4): COVID-19 ,  エピジェネティクス ,  転写制御 ,  遺伝子修復
Research theme for competitive and other funds  (1):
  • 2015 - 2016 不活性X染色体の高次構造制御に関与する新規因子群とその進化
Papers (8):
  • Janna Luessing, Maryam Sakhteh, Naoyuki Sarai, Louise Frizzell, Nikolay Tsanov, Kiefer Olaf Ramberg, Silvia Maretto, Peter Bernard Crowley, Noel Francis Lowndes. The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair. Cell Reports. 2021. 35. 13. 109306-109306
  • Mahesh Bachu, Tomohiko Tamura, Chao Chen, Ankur Narain, Vishal Nehru, Naoyuki Sarai, Sukhendu B. Ghosh, Anu Ghosh, Raghuveer Kavarthapu, Maria L. Dufau, et al. A versatile mouse model of epitope-tagged histone H3.3 to study epigenome dynamics. Journal of Biological Chemistry. 2019. 294. 6. 1904-1914
  • Ryota Ouda, Naoyuki Sarai, Vishal Nehru, Mira C. Patel, Maxime Debrosse, Mahesh Bachu, Răzvan V. Chereji, Peter R. Eriksson, David J. Clark, Keiko Ozato. SPT6 interacts with NSD2 and facilitates interferon-induced transcription. FEBS Letters. 2018. 592. 10. 1681-1692
  • Naoyuki Sarai, Keisuke Nimura, Tomohiko Tamura, Tomohiko Kanno, Mira C Patel, Tom D Heightman, Kiyoe Ura, Keiko Ozato. WHSC1 links transcription elongation to HIRA-mediated histone H3.3 deposition. The EMBO Journal. 2013. 32. 17. 2392-2406
  • Mira C. Patel, Maxime Debrosse, Matthew Smith, Anup Dey, Walter Huynh, Naoyuki Sarai, Tom D. Heightman, Tomohiko Tamura, Keiko Ozato. BRD4 Coordinates Recruitment of Pause Release Factor P-TEFb and the Pausing Complex NELF/DSIF To Regulate Transcription Elongation of Interferon-Stimulated Genes. Molecular and Cellular Biology. 2013. 33. 12. 2497-2507
more...
MISC (4):
  • Keiko Ozato, Monica Gupta, Naoyuki Sarai, Herbert Morse, Leonidas Platanias, Huabao Xiong, Mahesh Bachu. ID: 211. Cytokine. 2015. 76. 1. 103-103
  • K. Ozato, N. Sarai, M. Patel, M. Debrosse, T. Heightman, T. Tamura, K. Ura. O029 Chromatin exchange in interferon induced transcription. Cytokine. 2012. 59. 3. 511-511
  • Keiko Ozato, Naoyuki Sarai, Mira Patel, Natarajan Ayithan, Tomohiko Tamura. SS3-1 Chromatin dynamics in interferon signaling: Analysis of the histone H3.3 deposition. Cytokine. 2010. 52. 1-2. 15-15
  • N. Sarai, W. Kagawa, H. Kurumizaka, S. Yokoyama. Crystal Structure of Holliday Junction Resolvase ST1444. 2007
Education (3):
  • 2005 - 2008 The University of Tokyo Graduate School of Science Doctoral Program Department of Biophysics and Biochemistry
  • 2003 - 2005 The University of Tokyo Graduate School of Science
  • 1999 - 2003 The University of Tokyo
Work history (9):
  • 2023/03 - 現在 Kagoshima University
  • 2022/07 - 2023/02 オンコリスバイオファーマ株式会社
  • 2019/02 - 2019/12 オックスフォード大学 研究員
  • 2016/06 - 2019/01 アイルランド国立大学ゴールウェイ校 研究員
  • 2014/04 - 2016/05 RIKEN
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Awards (1):
  • 2013/11 - The Fellows Award for Research Excellence, National Institute of Health 2013
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