Matsuda Yudai

マツダユウダイ | Matsuda Yudai

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://staffweb1.cityu.edu.hk/ymatsuda/

Research field (2)： Bioorganic chemistry , Environmental and pharmaceutical development resources

Research keywords (4)： Natural Product Chemistry , Biosynthesis , Filamentous Fungi , Genome Mining

Research theme for competitive and other funds (15)：

2025 - 2027 Global genome mining in fungi for the discovery of hidden families of biosynthetic enzymes and associated natural products
2023 - 2026 Global genome mining for unexploited bioactive natural products in filamentous fungi
2022 - 2024 Broadening the chemical space of fungal meroterpenoids and the enzymatic repertoire for their biosynthesis
2020 - 2022 Comprehensive Understanding and Engineering of Fungal Xanthone Biosynthesis
2020 - 2022 Synthetic Biological Studies on Fungal Antitumor Polyketides Violaceoids by Utilizing the Replication-Cycle Reaction Method

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Papers (53)：

Qiaolin Ji, Xingxing Wei, Shengkun Liu, Yudai Matsuda. Involvement of a Noncanonical Polyketide Synthase-Nonribosomal Peptide Synthetase Hybrid in the Biosynthesis of Sterol-C4-methyl Oxidase Inhibitor PF1163A. Organic Letters. 2024
Qiaolin JI, Yudai Matsuda. Biosynthesis of Depsides, Depsidones, and Diphenyl Ethers from Fungi and Lichens. Asian Journal of Organic Chemistry. 2024
Zerui Yang, Wei Shao, Yudai Matsuda, Linqi Song. iResNetDM: An interpretable deep learning approach for four types of DNA methylation modification prediction. Computational and Structural Biotechnology Journal. 2024. 23. 4214-4221
Longhui Yu, Hiroshige Ogawa, Shangzhao Li, Tsoh Lam Cheung, Wenchao Liu, Dexiu Yan, Yudai Matsuda, Yusuke Kobayashi, Zhihong Guo, Kotaro Ikeda, et al. Concise Synthesis of Cyctetryptomycin A and B Enabled by Zr-Catalyzed Dimerization. Angewandte Chemie International Edition. 2024. e202414295
Hang Wang, Chao Peng, Xiao-Xuan Chen, Hao-Yang Wang, Run Yang, Hao Xiang, Qiu-Fen Hu, Ling Liu, Lung Wa Chung, Yudai Matsuda, et al. Structural and Computational Insights into the Noncanonical Aromatization in Fungal Polyketide Biosynthesis. ACS Catalysis. 2024. 10796-10805

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MISC (9)：

Jia Tang, Yudai Matsuda. Functional analysis of transmembrane terpene cyclases involved in fungal meroterpenoid biosynthesis. Methods in Enzymology. 2024
董佳钰, 李敏, 肖宗华, 胡明, Yudai Matsuda, 汪伟光. 米曲霉异源表达天然产物研究进展. 合成生物学. 2023. 3. 6. 1126-1149
Xingxing Wei, Wei Guang Wang, Yudai Matsuda. Branching and converging pathways in fungal natural product biosynthesis. Fungal Biology and Biotechnology. 2022. 9. 1
Yudai Matsuda, Ikuro Abe. Fungal Meroterpenoids. Comprehensive Natural Products III. 2020. 445-478
Hitomi Nakamura, Yudai Matsuda, Ikuro Abe. Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways. Natural Product Reports. 2018. 35. 7. 633-645

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Lectures and oral presentations (56)：

Global Genome Mining in Fungi for Natural Product Discovery
(2024 US-Japan Seminar on the Biosynthesis of Natural Products)
Global genome mining in fungi for natural product discovery
(Frontiers in Medicinal Chemistry: A Forum for Innovation and Discovery)
Oxidative rearrangements in fungal meroterpenoid biosynthesis
(2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (2023 ICCP450/JSSX))
Discovery and characterization of fungal depside synthases
(The 65th Symposium on the Chemistry of Natural Products 2023)
Biosynthesis of Fungal Meroditerpenoids Setosusin and Brevione E
(2nd JNU-UTokyo Joint Seminar on Natural Product Biosynthesis)

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Education (3)：

- 2015 The University of Tokyo Ph.D., Graduate School of Pharmaceutical Sciences
2010 - 2012 The University of Tokyo Graduate School of Pharmaceutical Sciences M.Sc., Department of Pharmaceutical Sciences
2006 - 2010 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Professional career (1)：

Work history (8)：

2024/07 - 現在 City University of Hong Kong Department of Chemistry Associate Professor
2018/04 - 2024/06 City University of Hong Kong Department of Chemistry Assistant Professor
2017/10 - 2018/03 The University of Tokyo Graduate School of Pharmaceutical Sciences Project Researcher
2015/10 - 2017/09 Technical University of Denmark Department of Biotechnology and Biomedicine Postdoc
2014/04 - 2015/09 The University of Tokyo Graduate School of Pharmaceutical Sciences Assistant Professor

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Awards (8)：

2024/09 - American Society of Pharmacognosy Jack L. Beal Award
2023/10 - Stanford University Stanford's top 2% most highly cited scientists 2023
2022/11 - Stanford University Stanford's top 2% most highly cited scientists 2022
2017/02 - 公益財団法人井上科学振興財団井上研究奨励賞
2016/09 - Reaxys Finalist, Reaxys PhD Prize

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