Rchr
J-GLOBAL ID：202401013233729710
Update date: Sep. 09, 2024
Wakisaka Yoshinobu
ワキサカ ヨシノブ | Wakisaka Yoshinobu
Affiliation and department：
Job title：
Associate Professor
Research field (5)：
Internal medicine - General
, Neurosurgery
, Neurology
, Experimental pathology
, Neuroanatomy and physiology
Research keywords (5)：
Cerebrovascular diseases
, Ischemic stroke
, Intracerebral hemorrhage
, Dementia
, Geriatric diseases
Research theme for competitive and other funds (5)：
- 2022 - 2025 加齢が脳梗塞後のペリサイトを介した組織修復・内因性機能回復機構に与える影響の解明
- 2019 - 2022 Effect of Nox4, a major NADPH-dependent reactive oxygen species-producing enzyme, on cerebral demyelination and cognitive impairment due to chronic cerebral hypoperfusion
- 2015 - 2019 The impact of cognitive impairment on stroke recurrence in the patients with ischemic stroke
- 2014 - 2018 Pathogenic mechanism of spontaneous hypertensive intracerebral hemorrhage focused on ROS-producing enzyme Nox4 expressed in brain microvascular pericytes
- 2014 - 2017 Elucidation of mechiansms underlying Nox4-mediated enhancement of hypoxic responses in endothelial cells
Papers (68)：
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Fumi Irie, Ryu Matsuo, Satomi Mezuki, Yoshinobu Wakisaka, Masahiro Kamouchi, Takanari Kitazono, Tetsuro Ago. Effect of smoking status on clinical outcomes after reperfusion therapy for acute ischemic stroke. Scientific reports. 2024. 14. 1. 9290-9290
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Fumi Irie, Koutarou Matsumoto, Ryu Matsuo, Yasunobu Nohara, Yoshinobu Wakisaka, Tetsuro Ago, Naoki Nakashima, Takanari Kitazono, Masahiro Kamouchi. Predictive Performance of Machine Learning-Based Models for Poststroke Clinical Outcomes in Comparison With Conventional Prognostic Scores: Multicenter, Hospital-Based Observational Study. JMIR AI. 2024. 3. e46840
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Satomi Mezuki, Ryu Matsuo, Fumi Irie, Yuji Shono, Takahiro Kuwashiro, Hiroshi Sugimori, Yoshinobu Wakisaka, Tetsuro Ago, Masahiro Kamouchi, Takanari Kitazono. Body temperature in the acute phase and clinical outcomes after acute ischemic stroke. PloS one. 2024. 19. 1. e0296639
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Kayo Wakisaka, Ryu Matsuo, Fumi Irie, Yoshinobu Wakisaka, Tetsuro Ago, Masahiro Kamouchi, Takanari Kitazono. Association between abdominal adiposity and clinical outcomes in patients with acute ischemic stroke. PloS one. 2024. 19. 1. e0296833
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Takuya Okata, Tsutomu Yoshioka, Yoshinobu Wakisaka, Tetsuro Ago, Toshiyasu Ogata, Jiro Kitayama. [A case of recurrent stroke with carotid-web despite dabigatran treatment successfully treated by carotid endarterectomy]. Rinsho shinkeigaku = Clinical neurology. 2023. 63. 9. 577-581
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MISC (123)：
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高島 正光, 脇坂 義信, 北園 孝成. 【一次救急における初期対応】各症状への対応 運動障害. 臨牀と研究. 2024. 101. 5. 566-570
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中村 晋之, 清原 卓也, 脇坂 義信, 吾郷 哲朗, 北園 孝成. 「Neurovascular unit/Neurovasculome」 脳梗塞後のneurovascular unit修復過程におけるペリサイト保護戦略. 脳循環代謝. 2023. 35. 1. 52-52
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松尾 龍, 脇坂 義信, 吾郷 哲朗, 鴨打 正浩, 北園 孝成. 「データベース研究の新展開」 地域疾患コホート「福岡脳卒中データベース研究」の新展開. 脳循環代謝. 2023. 35. 1. 59-59
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日高 壮意, 中村 晋之, 吉野 文隆, 高島 正光, 清原 卓也, 脇坂 義信, 吾郷 哲朗, 北園 孝成. マクロファージの脳梗塞後組織内浸潤はペリサイトの遊走及び組織修復に重要である. 脳循環代謝. 2023. 35. 1. 78-78
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日高 壮意, 中村 晋之, 吉野 文隆, 高島 正光, 清原 卓也, 脇坂 義信, 吾郷 哲朗, 北園 孝成. Nox4はペリサイトおよびマクロファージの動員を促進し脳梗塞後の血流回復と組織修復をもたらす. 脳循環代謝. 2023. 35. 1. 78-78
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