Nobusue Hiroyuki

ノブスエヒロユキ | Nobusue Hiroyuki

Affiliation and department：

Research field (1)： Tumor biology

Research theme for competitive and other funds (9)：

2024 - 2027 アクチン結合性転写調節因子MKL1活性化を起点とするがん幹細胞薬剤耐性機構の解明
2023 - 2026 Elucidation of adipocyte-to-cancer-associated fibroblast conversion mechanism and establishment of strategies to control cancer microenvironment
2023 - 2026 Overcoming the drug resistance through drug repositioning in esophageal cancer
2021 - 2024 アクチン動態が制御するがん幹細胞の薬剤耐性機構の解明と治療戦略の構築
2020 - 2023 Elucidation of the molecular mechanism of cancer-related fibroblast induction and regulation of the tumor microenvironment based on its inhibition

Show all

Papers (16)：

Atsuko Sugimoto, Takahiro Watanabe, Kazuhiro Matsuoka, Yusuke Okuno, Yusuke Yanagi, Yohei Narita, Seiyo Mabuchi, Hiroyuki Nobusue, Eiji Sugihara, Masaya Hirayama, et al. Growth Transformation of B Cells by Epstein-Barr Virus Requires IMPDH2 Induction and Nucleolar Hypertrophy. Microbiology spectrum. 2023. 11. 4. e0044023
Takatsune Shimizu, Eiji Sugihara, Hideyuki Takeshima, Hiroyuki Nobusue, Rui Yamaguchi, Sayaka Yamaguchi-Iwai, Yumi Fukuchi, Toshikazu Ushijima, Akihiro Muto, Hideyuki Saya. Depletion of R270C Mutant p53 in Osteosarcoma Attenuates Cell Growth but Does Not Prevent Invasion and Metastasis In Vivo. Cells. 2022. 11. 22
Megumi Uetaki, Nobuyuki Onishi, Yoshinao Oki, Takatsune Shimizu, Eiji Sugihara, Oltea Sampetrean, Takashi Watanabe, Hisano Yanagi, Kiyoshi Suda, Hiroya Fujii, et al. Regulatory roles of fibronectin and integrin α5 in reorganization of the actin cytoskeleton and completion of adipogenesis. Molecular biology of the cell. 2022. 33. 9. ar78
Takatsune Shimizu, Kiyomi Kimura, Eiji Sugihara, Sayaka Yamaguchi-Iwai, Hiroyuki Nobusue, Oltea Sampetrean, Yuji Otsuki, Yumi Fukuchi, Kaori Saitoh, Keiko Kato, et al. MEK inhibition preferentially suppresses anchorage-independent growth in osteosarcoma cells and decreases tumors in vivo. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2021. 39. 12. 2732-2743
Akiyoshi Kasuga, Takashi Semba, Ryo Sato, Hiroyuki Nobusue, Eiji Sugihara, Hiromasa Takaishi, Takanori Kanai, Hideyuki Saya, Yoshimi Arima. Oncogenic KRAS-expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice. Cancer science. 2021. 112. 5. 1822-1838

ｍore...

Books (2)：

マウス・ラットモデル作製・解析プロフェッショナル : あなたの研究をステップアップさせる最新・最適手技
羊土社 2021 ISBN:9784758121125
細胞工学2014年9月号 Vol.33 No.9
学研メディカル秀潤社 2014 ISBN:4780901588

Education (3)：

2005 - 2008 Nihon University Graduate School of Bioresource Sciences
2003 - 2005 Nihon University Graduate School of Bioresource Sciences
1999 - 2003 Nihon University College of Bioresource Sciences

Professional career (1)：

生物資源科学博士 (日本大学大学院生物資源科学研究科)

Work history (3)：

2013/04 - 2021/08 Keio University School of Medicine Institute for Advanced Medical Research (Division of Gene Regulation)
2010/04 - 2013/03 Nihon University College of Bioresource Sciences
2008/12 - 2010/03 Nihon University

Committee career (1)：

2024/01 - 現在 The Japanese Cancer Association Councilor

Awards (2)：

2010 - Japanese Society of Animal Science Excellent presentation award
2009 - Japanese Society of Animal Science Excellent presentation award

Association Membership(s) (2)：

The Japanese Cancer Association , The Molecular Biology Society of Japan

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page