Rchr
J-GLOBAL ID：202401015497944697
Update date: Aug. 28, 2024
Fujimura Akiko
フジムラ アキコ | Fujimura Akiko
Affiliation and department：
Research field (4)：
Chemical biology
, Structural biochemistry
, Molecular biology
, Cell biology
Research keywords (8)：
Cryo-EM
, TLR
, 自然免疫
, ヌクレオソーム
, 人工酵素
, タンパク質翻訳後修飾
, 細胞分裂
, nucleolus
Research theme for competitive and other funds (2)：
- 2019 - 2024 化学触媒ツールの開発を基軸としたヒストン修飾とDNA修復の相関解明
- 2009 - 2011 細胞外環境に応答したリボソームRNA遺伝子のメチル化制御メカニズムの解明
Papers (12)：
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Akiko Fujimura, Hisashi Ishida, Tamiko Nozaki, Shuhei Terada, Yuto Azumaya, Tadashi Ishiguro, Yugo R Kamimura, Tomoya Kujirai, Hitoshi Kurumizaka, Hidetoshi Kono, et al. Designer Adaptor Proteins for Functional Conversion of Peptides to Small-Molecule Ligands toward In-Cell Catalytic Protein Modification. ACS central science. 2023. 9. 11. 2115-2128
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Zhikuan Zhang, Takuma Shibata, Akiko Fujimura, Jiro Kitaura, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu. Structural basis for thioredoxin-mediated suppression of NLRP1 inflammasome. Nature. 2023. 622. 7981. 188-194
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Kentaro Sakaniwa, Akiko Fujimura, Takuma Shibata, Hideki Shigematsu, Toru Ekimoto, Masaki Yamamoto, Mitsunori Ikeguchi, Kensuke Miyake, Umeharu Ohto, Toshiyuki Shimizu. TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction. Nature communications. 2023. 14. 1. 164-164
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Yusuke Fujiwara, Yuki Yamanashi, Akiko Fujimura, Yuko Sato, Tomoya Kujirai, Hitoshi Kurumizaka, Hiroshi Kimura, Kenzo Yamatsugu, Shigehiro A Kawashima, Motomu Kanai. Live-cell epigenome manipulation by synthetic histone acetylation catalyst system. Proceedings of the National Academy of Sciences of the United States of America. 2021. 118. 4
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Akiko Fujimura, Yuki Hayashi, Kazashi Kato, Yuichiro Kogure, Mutsuro Kameyama, Haruka Shimamoto, Hiroaki Daitoku, Akiyoshi Fukamizu, Toru Hirota, Keiji Kimura. Identification of a novel nucleolar protein complex required for mitotic chromosome segregation through centromeric accumulation of Aurora B. Nucleic acids research. 2020. 48. 12. 6583-6596
ｍore...
Association Membership(s) (1)：
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