HOSOKAWA YUSEI

ホソカワユウセイ | HOSOKAWA YUSEI

Affiliation and department：
Other affiliations (1)：

Research field (1)： Metabolism and endocrinology

Research keywords (3)： MASLD / MASH (NAFLD / NASH) , インスリン抵抗性 , 脂肪組織

Research theme for competitive and other funds (2)：

Papers (10)：

Makoto Imamori, Tetsuya Hosooka, Yukiko Imi, Yusei Hosokawa, Kanji Yamaguchi, Yoshito Itoh, Wataru Ogawa. Thrombospondin-1 promotes liver fibrosis by enhancing TGF-β action in hepatic stellate cells. Biochemical and biophysical research communications. 2024. 693. 149369-149369
Nanaho Kasahara, Yukiko Imi, Reina Amano, Masakazu Shinohara, Kumiko Okada, Yusei Hosokawa, Makoto Imamori, Chiaki Tomimoto, Jun Kunisawa, Shigenobu Kishino, et al. A gut microbial metabolite of linoleic acid ameliorates liver fibrosis by inhibiting TGF-β signaling in hepatic stellate cells. Scientific reports. 2023. 13. 1. 18983-18983
Yusei Hosokawa, Tetsuya Hosooka, Makoto Imamori, Kanji Yamaguchi, Yoshito Itoh, Wataru Ogawa. Adipose tissue insulin resistance exacerbates liver inflammation and fibrosis in a diet-induced NASH model. Hepatology communications. 2023. 7. 6
Shuhei Kanagaki, Yusuke Tsutsui, Naoki Kobayashi, Takashi Komine, Minoru Ito, Yunike Akasaka, Michiaki Nagasawa, Tomohiro Ide, Naoki Omae, Kazuhisa Nakao, et al. Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins. iScience. 2023. 26. 4. 106293-106293
Yuko Nabatame, Tetsuya Hosooka, Chikako Aoki, Yusei Hosokawa, Makoto Imamori, Yoshikazu Tamori, Yuko Okamatsu-Ogura, Takeshi Yoneshiro, Shingo Kajimura, Masayuki Saito, et al. Kruppel-like factor 15 regulates fuel switching between glucose and fatty acids in brown adipocytes. Journal of diabetes investigation. 2021. 12. 7. 1144-1151

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MISC (8)：

細川友誠, 小川渉. 【NAFLD/NASHの診断と治療の進歩】NAFLD/NASHの治療の進歩糖尿病とNAFLD/NASH/MAFLD 臨床での考え方と対策. Progress in Medicine. 2023. 43. 5. 435-439
細岡哲也, 伊美友紀子, 細川友誠, 今森真, 小川渉. 脂肪組織インスリン抵抗性とNAFLD/NASH. 糖尿病・内分泌代謝科. 2022. 55. 4. 468-476
細川友誠, 小川渉. 【インスリン分泌不全とインスリン抵抗性】. さかえ: 月刊糖尿病ライフ. 2022. 62. 8. 28-34
細川友誠, 小川渉. 【非アルコール性脂肪性肝疾患(NAFLD)-臨床の現状と課題-】糖尿病とNAFLD/NASH. 消化器内科. 2022. 4. 2. 26-34
Yusei Hosokawa, Wataru Ogawa. SGLT2 inhibitors for genetic and acquired insulin resistance: Considerations for clinical use. Journal of diabetes investigation. 2020. 11. 6. 1431-1433

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Lectures and oral presentations (7)：

白色脂肪組織のインスリン抵抗性によるNAFLD/NASHの発症・進展機構の解明
(第44回肥満学会 2023)
Quantitative analysis of metformin-induced glucose excretion in the intestine
(The 83rd American Diabetes Association Scientific Sessions. 2023)
脂肪組織のインスリン抵抗性は,食餌誘導性NASHモデルの肝臓における炎症と線維化を促進し,より均質的なNASHの発症に寄与する
(第66回日本糖尿病学会年次学術総会 2023)
脂肪組織のインスリン抵抗性は、食餌誘導性NASHモデルの肝臓における炎症と線維化を促進し、より均質的なNASHの発症に寄与する
(第58回日本臨床分子医学会学術総会 2023)
脂肪細胞特異的LTA4H過剰発現は脂肪組織の健康的増大を介して肥満による代謝障害発症を抑制する
(第43回肥満学会総会 2022)

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Education (2)：

Professional career (2)：

Work history (4)：

Committee career (1)：

Awards (8)：

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