Rchr
J-GLOBAL ID：202401020721347075
Update date: May. 22, 2024
tonosaki madoka
tonosaki madoka
Research field (1)：
Fetal medicine/Pediatrics
Research keywords (1)：
in utero electroporation, time lapse imaging
Research theme for competitive and other funds (2)：
- 2018 - 2022 Does hereditary microcephalic responsible gene ASPM control a cell cycle and cell death in the neurogenesis process?
- 2016 - 2019 Analysis of lifelong molecular function of ASPM, responsible gene for human hereditary microcephaly, in the brain
Papers (4)：
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Madoka Tonosaki, Akira Fujimori, Takeshi Yaoi, Kyoko Itoh. Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLOS ONE. 2023. 18. 11. e0294893
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Miyuki Mori, So Tando, Hiroshi Ogi, Madoka Tonosaki, Takeshi Yaoi, Akira Fujimori, Kyoko Itoh. Loss of abnormal spindle-like, microcephaly-associated (Aspm) disrupts female folliculogenesis in mice during maturation and aging. Reproductive Biology. 2022. 22. 3. 100673-100673
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Madoka Tonosaki, Kyoko Itoh, Masafumi Umekage, Tomokazu Kishimoto, Takeshi Yaoi, Vance P. Lemmon, Shinji Fushiki. L1cam Is Crucial for Cell Locomotion and Terminal Translocation of the Soma in Radial Migration during Murine Corticogenesis. PLoS ONE. 2014. 9. 1. e86186
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Tomokazu Kishimoto, Kyoko Itoh, Masafumi Umekage, Madoka Tonosaki, Takeshi Yaoi, Kenji Fukui, Vance P. Lemmon, Shinji Fushiki. Downregulation of L1 perturbs neuronal migration and alters the expression of transcription factors in murine neocortex. Journal of Neuroscience Research. 2012. 91. 1. 42-50
Lectures and oral presentations (4)：
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ヒト先天性小頭症(MCPH5)モデルマウス(Aspmコンディショナルノックアウト)の解析
(第63回日本神経病理学会総会 2022)
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Presumptive function of microcephaly related gene Aspm during murine brain development
(ICN2018 2018)
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細胞接着分子L1camはマウス大脳皮質形成過程における神経細胞放射状遊走に不可欠である
(第55回日本神経病理学会総会 2014)
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神経細胞接着分子L1camは大脳皮質形成過程における放射状神経細胞移動に必須である
(第56回日本小児神経学会学術集会 2014)
Education (1)：
- 2007 - 2011 Graduate School of Medical Science, Kyoto Prefectural University of Medicine Graduate School of Medical Science
Professional career (1)：
- Doctor of Philosophy (Kyoto Prefectural University of Medicine)
Work history (4)：
- 2024/04 - 現在 Kyoto Prefectural University of Medicine Reseach Assistant
- 2023/10 - 2024/03 Kyoto Prefectural University of Medicine Reseach Assistant
- 2014/04 - 2023/03 Kyoto Prefectural University of Medicine Project researcher
- 2011/04 - 2014/03 Kyoto Prefectural University of Medicine Reseach Assistant
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