Research field (4)：
Applied biofunctional and bioprocess engineering
, Structural biochemistry
, Molecular biology
, Molecular biochemistry
Research keywords (4)：
Transdermal vaccine
, peptide
, Drug delivery
, directed evolution
Research theme for competitive and other funds (2)：
2024 - 2027 Creation of non-invasive vaccines based on nanocoating technology of biomolecule
2013 - 2013 バキュロウイルス由来新奇コンドロイチンリアーゼの立体構造解明と機能改変
Papers (9)：
Rashedul Islam, Fahmida Habib Nabila, Rie Wakabayashi, Yoshirou Kawaguchi, Noriho Kamiya, Muhammad Moniruzzaman, Masahiro Goto. Ionic Liquid-Based Immunization Patch for the Transdermal Delivery of Antigens. Molecules. 2024
Takenobu Katagiri, Sho Tsukamoto, Mai Kuratani, Tsuji S, Kensuke Nakamura, Ohte S, Yoshirou Kawaguchi, Kiyosumi Takaishi. A blocking monoclonal antibody reveals dimerization of intracellular domains of ALK2 associated with genetic disorders. Nature communications. 2023
Hidenori Yano, Daisuke Nishimiya, Kawaguchi Y, Tamura M, Hashimoto R. Discovery of potent and specific inhibitors targeting the active site of MMP-9 from the engineered SPINK2 library. PloS one. 2020
Daisuke Nishimiya, Yoshirou Kawaguchi, Shiho Kodama, Hatsumi Nasu, Hidenori Yano, Aya Yamaguchi, Masakazu Tamura, Ryuji Hashimoto. A protein scaffold, engineered SPINK2, for generation of inhibitors with high affinity and specificity against target proteases. Scientific Reports. 2019. 9. 1
Mitsuhiro Iwamoto, Yukiko Sekiguchi, Kensuke Nakamura, Yoshirou Kawaguchi, Takeshi Honda, Jun Hasegawa. Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification. PLOS ONE. 2018. 13. 2
2009 - 2014 Kyushu University Graduate School of Systems Life Sciences
Work history (2)：
2023/11 - 現在 Kyushu University Faculty of Engineering Department of Applied Chemistry Assistant Professor
2014/04 - 2023/10 DAIICHI SANKYO COMPANY, LIMITED
Association Membership(s) (4)：
The Society of Chemical Engineers, Japan
, The Molecular Biology Society of Japan
, The Society for Biotechnology, Japan
, The Japan Society of Drug Delivery System
