Rchr
J-GLOBAL ID:200901000007031155   Update date: Mar. 21, 2024

Yamashita Satoshi

ヤマシタ サトシ | Yamashita Satoshi
Affiliation and department:
Homepage URL  (1): https://www.acoffice.jp/mithp/KgApp?resId=S000123
Research field  (4): Genomics ,  Molecular biology ,  Applied biochemistry ,  Tumor biology
Research keywords  (6): DNA methylation ,  epigenome ,  ゲノム ,  cancer ,  mutation ,  分析化学
Research theme for competitive and other funds  (10):
  • 2021 - 2024 Synthetic lethality with gene silencing
  • 2021 - 2024 Revealing specific local invasion mechanism in CNS using small cell lung cancer metastasis cell lines
  • 2019 - 2022 Identification of individual carcinogenic factors by mutation signature analysis in normal human tissues
  • 2016 - 2019 Quantification of ultra-rare somatic mutations using molecular barcode and risk assessment of cancer
  • 2016 - 2018 enome-wide DNA methylation profiling identifies primary central nervous system lymphomas as a distinct entity from systemic diffuse large B-cell lymphomas
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Papers (149):
  • Akiko Sasaki, Hideyuki Takeshima, Satoshi Yamashita, Chikamasa Ichita, Jun Kawachi, Wataru Naito, Yui Ohashi, Chihiro Takeuchi, Masahide Fukuda, Yumi Furuichi, et al. Severe induction of aberrant DNA methylation by nodular gastritis in adults. Journal of gastroenterology. 2024
  • Chihiro Takeuchi, Satoshi Yamashita, Yu-Yu Liu, Hideyuki Takeshima, Akiko Sasaki, Masahide Fukuda, Taiki Hashimoto, Tomoaki Naka, Kenichi Ishizu, Shigeki Sekine, et al. Precancerous nature of intestinal metaplasia with increased chance of conversion and accelerated DNA methylation. Gut. 2023
  • 西山 和宏, 竹島 秀幸, 西中村 瞳, 服部 奈緒子, 竹内 千尋, 武田 はるな, 山下 聡, 小濱 和貴, 西川 博嘉, 牛島 俊和. 炎症を起こした消化管組織における白血球割合のマウスメチル化マーカーの確立. 日本消化器外科学会総会. 2023. 78回. P075-3
  • Nobuaki Arai, Naoko Hattori, Satoshi Yamashita, Yu-Yu Liu, Takahiro Ebata, Chihiro Takeuchi, Hideyuki Takeshima, Satoshi Fujii, Haruhiko Kondo, Hirofumi Mukai, et al. HSD17B4 methylation enhances glucose dependence of BT-474 breast cancer cells and increases lapatinib sensitivity. Breast Cancer Research and Treatment. 2023
  • Chihiro Takeuchi, Satoshi Yamashita, Yu-Yu Liu, Hideyuki Takeshima, Toshikazu Ushijima. Abstract 6024: Precancerous nature of intestinal metaplasia with accelerated DNA methylation along with altered epigenomic landscape. Cancer Research. 2023. 83. 7_Supplement. 6024-6024
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MISC (35):
  • Sho Tsuyuki, Hideyuki Takeshima, Yukinori Yamagata, Takayuki Ando, Satoshi Yamashita, Shin Maeda, Toshikazu Ushijima. Comparable somatic mutation profiles between gastric cancers with past H. pylori infection and current infection. CANCER SCIENCE. 2022. 113. 1661-1661
  • 佐々木重嘉, 久米賢, 立石健祐, 中村大志, 井林賢志, 山岸夢希, 齊藤邦昭, 小林啓一, 松下裕子, 日比谷優子, et al. Paired mutational analysis in secondary nervous system lymphoma and PCNSL systemic relapse reveals driver mutation candidates in the central nervous system. 日本脳腫瘍学会学術集会プログラム・抄録集. 2022. 40th
  • Tatsuro Watanabe, Hiroshi Ureshino, Satoshi Yamashita, Toshikazu Ushijima, Seiji Okada, Eisaburo Sueoka, Shinya Kimura. DNA hypermethylation of THEMIS, a regulator of T-Cell Receptor signaling, in adult T-cell leukemia-lymphoma. CANCER SCIENCE. 2021. 112. 260-260
  • 渡邉達郎, 吉田奈央, 吉田奈央, 山本雄大, 嬉野博志, 嬉野博志, 蒲池和晴, 蒲池和晴, 倉橋祐樹, 倉橋祐樹, et al. メチオニン代謝を介したHTLV-1感染細胞のエピゲノム調節. 日本HTLV-1学会学術集会. 2021. 7th
  • 渡邉達郎, 吉田奈央, 嬉野博志, 嬉野博志, 蒲池和晴, 蒲池和晴, 倉橋祐樹, 倉橋祐樹, 山本雄大, 山下聡, et al. 成人T細胞白血病/リンパ腫におけるT細胞受容体シグナル制御分子のDNAメチル化異常の細胞生物学的意義. 日本血液学会学術集会抄録(Web). 2020. 82nd
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Patents (4):
Education (3):
  • 1995 - 1998 The University of Tokyo The Graduate School of Engineering Department of Chemistry and Biotechnology
  • 1990 - 1992 The University of Tokyo The Graduate School of Engineering
  • 1986 - 1990 The University of Tokyo The Faculty of Engineering
Work history (9):
  • 2022/04 - 現在 Maebashi Institute of Technology
  • 2013/04 - 現在 Nagoya City University
  • 2010/04 - 2022/03 国立がん研究センター 研究所 ユニット長
  • 2011/04 - 2014/03 国立環境研究所 客員研究員
  • 2007/04 - 2010/03 国立がんセンター 研究所 発がん促進物質研究室長
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