Rchr
J-GLOBAL ID:200901001435612096
Update date: Jul. 17, 2024
YOSHIKI KORIYAMA
コオリヤマ ヨシキ | YOSHIKI KORIYAMA
Affiliation and department:
Homepage URL (1):
http://www.suzuka-u.ac.jp/
Research field (1):
Neuroscience - general
Research keywords (1):
CNS regeneration, apoptosis, survival signal, axonal regeneration, Alzheimer's disease, CNS degeneration、glaucoma
Research theme for competitive and other funds (25):
- 2022 - 2025 Optic nerve regeneration mechanism by nerve-glial linkage after injury
- 2021 - 2025 生活習慣病の新規概念「毒性終末糖化産物(Toxic AGEs)原因説」の確立
- 2021 - 2024 Elucidation of the mechanism of central nervous system regeneration by vitamin K for the treatment of cerebrovascular diseases
- 2021 - 2022 Elucidation of the mechanism of Alzheimer's disease through TAGE
- 2019 - 2022 Elucidation of the mechanism in Alzheimer's disease through advanced glycation end products by glyceraldehyde
- 2020 - 2021 終末糖化産物Glycer-AGEsのβチュブリン重合阻害によるがん細胞増殖抑制メカニズム
- 2018 - 2021 Elucidation of mechanisms underlying the link between nutritional modulation of gut microbiota and gut-multiorgan crosstalk that can promote health span extension in the elderly people
- 2016 - 2019 The role of molecular chaperone VCP in excitotoxin-induced cell death.
- 2016 - 2019 HSP70 targeting therapy for retinitis pigmentosa
- 2016 - 2019 現代の飲食物が関与する細胞内毒性終末糖化産物の生成/蓄積と各種細胞障害機序の解明
- 2014 - 2018 Activation mechanism of the cellular Factor XIII for nerve regeneration
- 2016 - 2018 HSP70を標的とした網膜色素変性症の新たな病態メカニズム解明と治療戦略
- 2015 - 2016 新規天然物リガンドの補酵素代替作用解析と難治性中枢神経疾患治療への応用
- 2013 - 2016 視神経再生過程におけるクロマチンダイナミクス解析と緑内障治療への応用
- 2011 - 2015 Involvement of FactorXIII-A in fish optic nerve regeneration
- 2013 - 2013 機能回復を目指した新規中枢神経再生モデルの開発
- 2013 - 2013 アストロサイト特異的Ndrg2によるグリア瘢痕形成制御と中枢神経再生
- 2013 - 2013 新規テトラヒドロビオプテリン代替化合物ライブラリーからの革新的脳・神経疾患治療薬の開発
- 2011 - 2011 イリドイド化合物ライブラリーからのSニトロシル化を標的とした新規緑内障治療薬の探索
- 2010 - 2011 新規細胞外マトリックスタンパク質による神経再生の分子基盤解明と緑内障治療への応用
- 2010 - 2010 一酸化窒素のタンパク質修飾による中枢神経細胞の内因性抗酸化機構活性化の研究
- 2010 - 2010 合成レチノイドAm80による損傷後中枢神経再生への応用
- 2009 - 2009 新規細胞外マトリックスタンパク質を用いた中枢神経再生・修復の技術開発
- 2007 - 2009 網膜におけるレチノイン酸誘導の一酸化窒素合成酵素の生理機能と神経再生への応用
- 2003 - 中枢神経軸索再生分子の機能解析と再生医療への応用
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Papers (86):
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Hayahide Ooi, Ayako Furukawa, Masayoshi Takeuchi, Yoshiki Koriyama. Toxic Advanced Glycation End-Products Inhibit Axonal Elongation Mediated by β-Tubulin Aggregation in Mice Optic Nerves. International Journal of Molecular Sciences. 2024. 25. 13. 7409-7409
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Hayahide Ooi, Yuki Asai, Yoshiki Koriyama, Masaaki Takahashi. Decreased Hepatic Functional Reserve Increases the Risk of Piperacillin/Tazobactam-Induced Abnormal Liver Enzyme Levels: A Retrospective Case-Control Study. The Annals of pharmacotherapy. 2024. 10600280241255837-10600280241255837
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Hayahide Ooi, Yoshiki Koriyama. Toxic Advanced Glycation End Product-Dependent Alzheimer’s Disease- Like Alternation in the Microtubule System. Current Alzheimer Research. 2024. 20. 10. 677-681
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Hayahide Ooi, Yuki Asai, Yoshiki Koriyama, Masaaki Takahashi. Effect of Ceftriaxone Dosage and Albumin-Bilirubin Score on the Risk of Ceftriaxone-Induced Liver Injury. Biol.Pharm.Bull. 2023. 46. 12. 1731-1736
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Effects of loading glucose on cognitive function in mice. 2023. 6. 2. 87-95
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MISC (76):
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Pathogenesis of Alzheimer's disease through toxic advanced glycation end-products (TAGE) and the possibility for therapeutic target. 2023. 839. 75-78
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Hayahide Ooi, Ayako Furukawa, Yoshiki Koriyama. Inhibitory effects of pyridoxamine against toxic advanced glycation end-products (TAGE)-induced axonal degeneration. Vitamin. 2022. 96. 11. 477-479
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大井 勇秀, 古川 絢子, 竹内 正義, 郡山 恵樹. SH-SY5Y細胞におけるTAGE標的タンパク質の探索とその生理学的意義. 第68回 日本薬学会東海支部大会要旨集. 2022
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竹内正義, 逆井(坂井)亜紀子, 高田尊信, 瀧野純一, 郡山恵樹, 古川絢子, 那須隆斗, 菊池千草, 長嶺憲太郎, 堀隆光, et al. Toxic AGEs (TAGE) as a new concept in the lifestyle-related diseases. 日本薬学会年会要旨集(Web). 2022. 142nd
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Ryuto Nasu, Ayako Furukawa, Masayoshi Takeuchi, Yoshiki Koriyama. Elucidation of the mechanism of Alzheimer's disease through glyceraldehyde-derived advanced glycation end-products. 2021. 5. 11. 64-67
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Books (4):
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Optic Nerve Regeneration in Lower Vertebrates and Mammals: Bridging the Gap.
2015
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Nitric oxide contributes retinal ganglion cell survival and axonal regeneration through protein S-nitrosylation.
2014
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Advances on Optic Nerve Regeneration and Therapeutic Strategies
2014
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Optic nerve regeneration in goldfish
2007
Lectures and oral presentations (126):
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HSP70 induction by ETAS®50 suppresses photoreceptor cell death caused by blue LEDs
(2024)
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微小管系における毒性終末糖化産物 (TAGE) 起因性のアルツハイマー病様変化
(第70回日本薬学会東海支部会総会・大会 2024)
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グリセルアルデヒド標的タンパク質の探索とその病理学的意義について
(第144回日本薬学会 2024)
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TAGE化β-チューブリンによる神経軸索伸長阻害に対するAGEs阻害剤の軽減作用
(第144回日本薬学会 2024)
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SH-SY5Y細胞におけるグリセルアルデヒド(GA)によるタウのリン酸化促進作用
(第144回日本薬学会 2024)
more...
Education (2):
- 2003 - Hokuriku University Graduate School, Division of Pharmaceutical Sciences BioPharmacology
- 1993 - 1997 Hokuriku University Faculty of Pharmaceutical Science Faculty of Pharmaceutical Sciences
Professional career (2):
- 博士 (薬学) (北陸大学)
- 博士(医学) (金沢大学)
Work history (8):
- 2021/04 - 現在 Suzuka University of Medical Science Graduate School and Faculty of Pharmaceutical Sciences Professor
- 2014/04 - 2021/03 Suzuka University of Medical Science
- 2012/08 - 2014/03 Kanazawa University Associate Professor
- 2007/04 - 2012/07 Graduate School of Medicine,University of Kanazawa Department of Molecular Neurobiology
- 2011/02 - 2011/03 ミシガン大医学部 神経学
- 2010/07 - 2010/11 Harvard University
- 2005/04 - 2007/03 Graduate School of Medicine,University of Kanazawa Department of Molecular Neurobiology
- 2002/04 - 2005/03 JST CREST
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Awards (26):
- 2022/12 - 緑の風記念三重医学研究振興会賞
- 2021/04 - 岡三加藤文化振興財団 研究助成
- 2020/03 - 三重県健康管理事業センターがん学術助成
- 2015/04 - 岡三加藤文化振興財団 研究助成
- 2013/08/01 - Adaptable and Seamless Technology transfer Program through target-driven R&D(JST)
- 2013/08/01 - Takeda Science Foundation
- 2013/04/01 - KAKEN
- 2013/02/27 - Hokuriku bank foundation for young investigators
- 2012/11/18 - Hokuriku Branch of the Pharmaceutical Society of Japan Award for Young Scientists
- 2011/08/11 - Foundation for overseas cooperative research of Kanazawa University
- 2011/08/01 - Adaptable and Seamless Technology transfer Program through target-driven R&D(JST)
- 2011/04/01 - Research Grants from the Ministry of Education, Culture, Sports, Science and Technology of
- 2010/11/14 - Japanese Society for Retinoid Research Muto Award
- 2010/08/01 - Mitani Scientific Foundation
- 2010/04/01 - KAKEN
- 2010/03 - Research foundation for pharmaceutical sciences
- 2009/08 - Award for young investigator
- 2009/07 - Research for Promoting Technological Seeds
- 2008/06 - Kanazawa University Young Award
- 2008 - KAKEN
- 2008 - Kanazawa University Awards for Young Scientist
- 2007 - Kanazawa University Awards for Young Scientist
- 2007 - KAKEN
- 2006 - Kanazawa University Awards for Young Scientist
- 2004 - Kanazawa Univercity COE supports
- 2003 - KAKEN
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Association Membership(s) (6):
Society for Neuroscience
, 日本生理学会
, The Pharmaceutical Society of Japan
, Japnan Society for Retinoid Research
, The Japanese pharmacological society
, 日本神経化学会
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