Inoue Keiichi

イノウエケイイチ | Inoue Keiichi

Affiliation and department：
Job title： Associate Professor
Homepage URL (2)： http://inoue.issp.u-tokyo.ac.jp/ , http://www.ach.nitech.ac.jp/~physchem/kandori/index_j.html

Research field (10)： Biophysics , Functional biochemistry , Structural biochemistry , Molecular biology , Biochemistry , Analytical chemistry , Basic physical chemistry , Bio-, chemical, and soft-matter physics , Optical engineering and photonics , Molecular biochemistry

Research keywords (1)： Rhodopsin, Optogenetics, Biomolecular Spectroscopy, Photoreceptor Protein, Laser Spectroscopy, Infrared Spectroscopy, Ultraviolet-Visible Spectroscopy, Molecular Science

Research theme for competitive and other funds (24)：

2022 - 2027 The analysis of structural dynamics of microbial rhodopsins
2021 - 2026 Elucidation of the mechanism of rhodopsin functions for optogenetics
2022 - 2025 生体分子スピントロニクスの開拓
2021 - 2025 Understanding of the ground principle underlying the expression of a wide variety of protein functions by studying microbial rhodopsins as a model system
2021 - 2024 ヘリオロドプシンの作動メカニズムの解明

2020 - 2023 Development of ultrasonic and magnetic field-sensitive receiver molecules and their application to muscle tissue formation promotion technology

2020 - 2023 Next generation non-invasive deep biological manipulation by combining biomolecular engineering and low physical energy logistics

2020 - 2023 Next-generation non-invasive biological deep-tissue manipulation by biomolecular engineering and low physical energy logistics

2020 - 2023 Development of sodium-selective optogenetic tools for super-precise optical neural manipulation

2020 - 2022 Theoretical and Experimental Modeling of Light-responsive Proteins in the Era of Optogenetics

2020 - 2022 Optical control of energy dynamics in mitochondria

2020 - 2022 Theoretical and Experimental Modeling of Light-responsive Proteins in the Era of Optogenetics

2018 - 2021 Structural dynamics study of microbial rhodopsins

2017 - 2021 The study on the transport mechanism of light-driven inward proton pump and its application to optogenetics

2017 - 2021 Methods for selecting and testing hypothesis in big data-driven science and its demonstration in materials, biology, and medicine

2015 - 2019 新規光受容タンパク質が先導する新しいオプトジェネティクス

2014 - 2017 A challenge for the creation of extremely long-wavelength absorbing rhodopsin by molecular and structural biological approach

2014 - 2017 ナトリウムポンプ型ロドプシンの輸送メカニズムの網羅的分光研究

2014 - 2016 細菌の走性における数的多様性の解明

2012 - 2014 光でナトリウムをポンプする新型ロドプシンの機能解明

2012 - 2014 「数」を視点とした走光性信号伝達過程における信号増幅機構の解明

2010 - 2012 特定領域研究「分子高次系機能解明のための分子科学」

2009 - 2011 2段階励起過渡回折格子法の開発と情報伝達タンパク質の光反応機構の解明と制御

2010 - 2011 時間分解分光法によるミクロからマクロにおよぶタンパク質の反応ダイナミクスの理解

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Papers (172)：

Takayoshi Fujiwara, Toshiaki Hosaka, Masumi Hasegawa-Takano, Yosuke Nishimura, Kento Tominaga, Kaho Mori, Satoshi Nishino, Yuno Takahashi, Tomomi Uchikubo-Kamo, Kazuharu Hanada, et al. Carotenoid pigments enhance rhodopsin-mediated phototrophy by light-harvesting and photocycle-accelerating. 2024
Shunki Takaramoto, Shai Fainsod, Takashi Nagata, Andrey Rozenberg, Oded Béjà, Keiichi Inoue. The roles of an extended N-terminal region and ETD motif in a pump-like cation channelrhodopsin discovered in a lake microbiome. Journal of Molecular Biology. 2024. 168844-168844
Tomohiro Ishizuka, Kano Suzuki, Masae Konno, Keisei Shibata, Yuma Kawasaki, Hidefumi Akiyama, Takeshi Murata, Keiichi Inoue. Light-driven Anion-Pumping Rhodopsin with Unique Cytoplasmic Anion-release Mechanism. Journal of Biological Chemistry. 2024. 107797-107797
Tempei Hatajiri, Shoya Sakamoto, Hidetoshi Kosaki, Zikang Tian, Miuko Tanaka, Toshiya Ideue, Keiichi Inoue, Daigo Miyajima, Shinji Miwa. Gilbert damping of NiFe thin films grown on two-dimensional chiral hybrid lead-iodide perovskites. Physical Review B. 2024. 110. 5. 054435-054435
Éva Bertalan, Masae Konno, María del Carmen Marín, Reza Bagherzadeh, Takashi Nagata, Leonid Brown, Keiichi Inoue, Ana-Nicoleta Bondar. Hydrogen-Bonding and Hydrophobic Interaction Networks as Structural Determinants of Microbial Rhodopsin Function. The Journal of Physical Chemistry B. 2024

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MISC (61)：

Manipulation of living organisms by magnetic fields: the challenge of magnetogenetics. 2024. 19-22
井上圭一, 今野雅恵, 川﨑佑真, Maria del Carmen MARIN. アスガルドアーキアの持つ内向きプロトンポンプ型ロドプシン:シゾロドプシン-Light-Driven Inward Proton Pumping Rhodopsin from Asgard Archaea: Schizorhodopsin. 生物物理 / 日本生物物理学会編. 2023. 63. 5. 257-260
井上圭一. ゲノム時代に変わりゆくロドプシン観. 酵素工学ニュース. 2023. 90. 6-12
永田崇, 川崎佑真, 今野雅恵, 今野雅恵, 長坂勇次郎, 青山真子, 片山耕大, 片山耕大, ROZENBERG Andrey, KACZMARCZYK Igor, et al. Unique characteristics in chromophore photoisomerization of the novel rhodopsin, bestrhodopsin. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
DEL CARMEN Marin Perez Maria, 今野雅恵, 八尾寛, 井上圭一. Functional Conversion of Light-driven Outward Proton Pumping Rhodopsin to Inward Proton Pump. 分子科学討論会講演プログラム&要旨(Web). 2023. 17th

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Patents (1)：

プロトンポンプおよびその利用

Books (5)：

未培養微生物研究の最新動向
シーエムシー出版 2023 ISBN:9784781317328
未来探究2050 : 東大30人の知性が読み解く世界
日経BP日本経済新聞出版本部,日経BPマーケティング (発売) 2021 ISBN:9784532358785
Optogenetics : light-sensing proteins and their applications in neuroscience and beyond
Springer 2021 ISBN:9789811587627
光と生命の事典
朝倉書店 2016 ISBN:9784254171617
Super-resolution infrared microspectroscopy for single cells
Wiley-VCH 2009 ISBN:9783527320172

Lectures and oral presentations (355)：

Spectroscopic Study on Carotenoid Binding Ion-Transporting Microbial Rhodopsins
(20th International Conference on Retinal Proteins 2024)
Pioneering the Next Revolution in Protein Mechanistic Insights with Cutting-Edge Methodologies
(20th International Conference on Retinal Proteins 2024)
New Photochemistry of Retinal Lead by Novel Microbial Rhodopsins
(Seminar at Siena University 2024)
Spectroscopic Study on New Types of Photochemistry in Microbial Rhodopsins
(Seminar IPCMS Strasbourg 2024)
Carotenoids in Microbial Rhodopsins: Emerging Roles in Expanding Rhodopsin Functionality
(Laboratoire d'Optique e;Bioschiences Seminar 2024)

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Works (1)：

オプトジェネティクス-光工学と遺伝学による行動制御技術の最前線-
2014 -

Education (1)：

- 2007 Kyoto University

Work history (3)：

2018/04 - 現在 The University of Tokyo The Institute for Solid State Physics Associate Professor
2016/04 - 2018/03 Nagoya Institute of Technology Graduate School of Engineering, Life Science and Applied Chemistry Associate Professor
2007/04 - 2016/03 Assistant Professor,Nagoya Institute of Technology

Committee career (21)：

2024/09 - 現在分子科学会顕彰委員会副委員長
2024/09 - 現在分子科学会運営委員
2024 - 現在日本生物物理学会分野別専門委員
2024/01 - 現在 Biophysics and Physicobiology Vice Editors-in-Chief
2023 - 現在日本生物物理学会代議員

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Awards (13)：

2024/08 - International Union of Photobiology (IUPB) Finsen Lecture Award
2020/09 - 分子科学会第5回分子科学国際学術賞微生物型ロドプシンの光機能発現メカニズムの研究
2020/03 - 光科学技術研究振興財団第2回晝馬輝夫光科学賞新奇な微生物型ロドプシンの光機能およびその光反応メカニズム
2019/11 - Millennium Science Forum 2019 Sir Martin Wood Prize Discovery and functional analysis of novel retinal proteins
2018/03 - 日本光生物学協会第4回日本光生物学協会奨励賞微生物型ロドプシンの機能・構造・メカニズム研究と新奇分子デザイン

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Association Membership(s) (8)：

日本化学会 , 日本生物物理学会 , 日本分光学会 , 分子科学会 , The chemical society of Japan , The biophysical society of Japan , The spectroscopical society of Japan , Japan society for molecular science

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