Rchr
J-GLOBAL ID:200901001626830085   Update date: Jul. 01, 2020

Akai Shuji

アカイ シュウジ | Akai Shuji
Affiliation and department:
Job title: Professor
Homepage URL  (1): http://handai-seizo.jp/
Research field  (4): Pharmaceuticals - chemistry and drug development ,  Synthetic organic chemistry ,  Bioorganic chemistry ,  Structural/physical organic chemistry
Research keywords  (6): fluorine chemistry ,  synthetic organic chemistry ,  enzymatic catalysts ,  medicinal chemistry ,  catalyst chemistry ,  organic chemistry
Research theme for competitive and other funds  (4):
  • Development of Lipase-Catalyzed Asymmetric Synthetic Methods
  • Development of asymmetric synthetic methods using enzymes
  • Total Synthesis of Biologically Active Natural Products
  • Development of novel synthetic methods utilizing sulfur-functional groups
Papers (73):
  • Koichi Higashio, Satoko Katsuragi, Dhiman Kundu, Niklas Adebar, Carmen Plass, Franziska Kühn, Harald Gröger, Shuji Akai. Continuous-Flow Dynamic Kinetic Resolution of Racemic Alcohols by Lipase-Oxovanadium Cocatalysis. Eur. J. Org. Chem. 2020. 13. 1961-1967
  • Kenzo Yahata, Yuki Kaneko, Shuji Akai. Cobalt-Catalyzed Hydroamination of Alkenes with 5-Substituted Tetrazoles: Facile Access to 2,5-Disubstituted Tetrazoles and Asymmetric Intermolecular Hydroaminations. Chem. Pharm. Bull. 2020. 68. 332-335
  • Takashi Ikawa, JingKai Sun, Akira Takagi, Shuji Akai. One-Pot Generation of Functionalized Benzynes from Readily Available 2-Hydroxyphenylboronic Acids. J. Org. Chem. 2020. 85. 3383-3392
  • Kengo Kasama, Hiroshi Aoyama, Shuji Akai. Enantiodivergent Synthesis of Axially Chiral Biphenyls from σ-Symmetric 1,1'-Biphenyl-2,6-diol Derivatives by Single Lipase-Catalyzed Acylative and Hydrolytic Desymmetrization. Eur. J. Org. 2020. 6. 654-661
  • Kenzo Yahata, Shin Yoshioka, Shuhei Hori, Shu Sakurai, Yuki Kaneko, Kai Hasegawa, Shuji Akai. One-Pot Formal Dehydrogenative Ketone Synthesis from Aldehydes and Non-Activated Hydrocarbons. Chem. Pharm. Bull. 2020. 68. 4. 336-338
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MISC (99):
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Books (1):
  • Dynamic Kinetic Resolution for Asymmetric Synthesis: Synergy of Enzyme and Metal Catalysts
    Academic Press 2018
Education (3):
  • - 1987 Osaka University Graduate School of Pharmaceutical Sciences
  • - 1982 Osaka University School of Pharmaceutical Sciences
  • - 1982 Osaka University Faculty of Pharmaceutical Sciences
Professional career (1):
  • (BLANK)
Work history (4):
  • 2005 - Osaka University
  • 2005 - Associate Professor, Osaka University
  • 1997 - 1998 Overseas Research Scholar at MIT, USA
  • 1989 - - Research Associate
Awards (2):
  • 2012 - Excellent Poster Award Dynamic Kinetic Resolution of Racemic Allyl Alcohols by Lipase-Vanadium Combo Catalysis
  • 2011/08 - JSPC Award for Excellence 2011 Asymmetric Synthesis of Allyl Esters via Vanadium-Lipase Combo Catalyzed Dynamic Kinetic Resolution
Association Membership(s) (8):
The Kinka Chemical Society, Japan ,  International Society of Heterocyclic Chemistry ,  The Society of Fluorine Chemistry, Japan ,  The Japanese Society for Process Chemistry ,  The Chemical Society of Japan ,  American Chemical Society ,  The Society of Synthetic Organic Chemistry, Japan ,  The Pharmeceutical Society of Japan
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