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J-GLOBAL ID：200901002148230561   Update date: Aug. 21, 2024

Noma Takafumi

ノマ タカフミ | Noma Takafumi
Affiliation and department：
Hiroshima Jyogakuin University Faculty of Human Life Studies, Department of Nutrition and Health Promotion

About Hiroshima Jyogakuin University Faculty of Human Life Studies, Department of Nutrition and Health Promotion


Job title： Professor
Research field  (5)： Medical biochemistry ,  Molecular biology ,  Genetics ,  Oral medicine ,  Pathobiochemistry
Research keywords  (5)： Regenerative Medicine ,  Rare genetic disease ,  Energy metabolism ,  Development and differentiation ,  Development
Research theme for competitive and other funds  (15)：
  • 2019 - 2022 Explore of the GBA translation regulatory mechanism by RNA epigenetics: To find the therapeutic targets for Gaucher disease
  • 2019 - 2022 Identification of signal targets in neutrophil differentiation
  • 2015 - 2018 重症複合型免疫不全を呈する希少難病(細網異形成症)の病態解明と治療法の開発
  • 2015 - 2018 患者口腔粘膜線維芽細胞を用いた新規遺伝子変異によるゴーシェ病発症メカニズムの解明
  • 2012 - 2015 Establishment of disease model system using patient-derived oral mucosa fibroblast-iPSCs and development of new therapy
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Papers (104)：
  • Jingxin Wang, Norikazu Saiki, Ayako Tanimura, Takafumi Noma, Akira Niwa, Tastutoshi Nakahata, Megumu K Saito. UK-5099, a mitochondrial pyruvate carrier inhibitor, recovers impaired neutrophil maturation caused by AK2 deficiency in human pluripotent stem cell models. Biochemical and biophysical research communications. 2023. 687. 149211-149211
  • Intan Ruspita, Pragnya Das, Keiko Miyoshi, Takafumi Noma, Malcolm L. Snead, Marianna Bei. Enam expression is regulated by Msx2. Developmental Dynamics. 2023
  • Taigo Horiguchi, Ayako Tanimura, Keiko Miyoshi, Hiroko Hagita, Hisanori Minami, Takafumi Noma. The Effect of Heterozygous Mutation of Adenylate Kinase 2 Gene on Neutrophil Differentiation. International Journal of Molecular Sciences. 2022. 23. 24. 16089
  • Keiko Miyoshi, Hiroko Hagita, Taigo Horiguchi, Ayako Tanimura, Takafumi Noma. Redefining GBA gene structure unveils the ability of Cap-independent, IRES-dependent gene regulation. Communications Biology. 2022. 5. 1. 639
  • Koichi Fujisawa, Maina Wakazaki, Aya Matsuzaki, Toshihiko Matsumoto, Naoki Yamamoto, Takafumi Noma, Taro Takami. Adenylate Kinase Isozyme 3 Regulates Mitochondrial Energy Metabolism and Knockout Alters HeLa Cell Metabolism. International Journal of Molecular Sciences. 2022. 23. 8. 4316
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MISC (30)：
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Books (29)：
  • CONTEMPORARY MODELS IN ECTODERMAL ORGAN DEVELOPMENT, MAINTENANCE AND REGENERATION
    Frontiers Media SA 2021
  • 生化学実習書 (第14版1刷)
    徳島大学大学院医歯薬学研究部分子医化学分野 2020
  • 生化学実習書 (第13版1刷)
    徳島大学大学院医歯薬学研究部分子医化学分野 2019
  • 生化学実習書 (第12版1刷)
    徳島大学大学院医歯薬学研究部分子医化学分野 2018
  • 生化学実習書 (第11版1刷)
    徳島大学大学院医歯薬学研究部分子医化学分野 2017
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Lectures and oral presentations  (110)：
  • 運動が遺伝子発現に与える影響の網羅的解析
    (四国歯学会第56回例会・徳島県歯科医学大会 2020)
  • 再生歯学戦略におけるヒト口腔粘膜由来繊維芽細胞の特性
    (四国歯学会第56回例会・徳島県歯科医学大会 2020)
  • 「めざせ健康長寿?生活習慣,栄養,遺伝子の視点から?」
    (広島女学院大学 管理栄養学会 秋季講演会 2018)
  • Possible roles of Sp6 in ameloblast differentiation
    (The 6th International Conference on Biology and Pathobiology of KLF/Sp Transcription Factors 2018)
  • Perturbation of gene regulateion in an in vitro amelogenesis imperfecta model
    (The 91st Annual Meeting of the Japanese Biochemical Society 2018)
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Works (2)：
  • ミトコンドリアにおける新たな代謝制御因子の発見と病気の関連
    2001 -
  • Identification of novel regulator in mitochondrial metabolism
    2001 -
Professional career (1)：
  • Medical Doctor (Kyoto University)
Work history (4)：
  • 2020/04 - 現在 Hiroshima Jogakuin University Faculty of Human Life Studies, Department of Nutrition and Health Promotion Professor
  • 2015/04 - 2020/03 徳島大学大学院医歯薬学研究部 分子医化学分野 教授
  • 2004/04 - 2014/03 The University of Tokushima Institute of Health Biosciences The University of Tokushima Graduate School
  • 2002/06 - 2004/03 The University of Tokushima Faculty of Dentistry
Committee career (7)：
  • 2002 - 四国歯学会 理事
  • 2002 - 歯科基礎医学会 評議員
  • 2002 - 日本生化学会 評議員
  • 2001 - 日本病態栄養学会 評議員
  • 歯科基礎医学会 理事, 評議員
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Awards (1)：
  • 2004/01/23 - The Koraku Foundation 康楽賞 Analysis for structure and function of adenylate kinase isozymes
Association Membership(s) (8)：
日本遺伝子治療学会 ,  The Japan Neuroscience Society ,  日本結合織学会 ,  Shikoku Society of Dental Research ,  The Molecular Biology Society of Japan ,  Japanese Association for Oral Biology ,  Japan Society of Metabolism and Clinical Nutrition ,  The Japanese Biochemical Society
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