Okumura Yuushi

オクムラユウシ | Okumura Yuushi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.hosp.med.tokushima-u.ac.jp/university/servlet/index?&level=4&reference=0/10002/5/30010/20032

Research field (3)： Pathobiochemistry , Medical biochemistry , Functional biochemistry

Research keywords (4)：阻害剤 , セリンプロテアーゼ , Inhibitor , Serine Protease

Research theme for competitive and other funds (14)：

2017 - 2023 骨密度関連SNPs近隣由来のmiRNAsによる骨代謝制御の検討
2018 - 2021 The development of the new therapeutic drug by targeting host proteases: A novel regulatory method for highly pathogenic infectious diseases.
2015 - 2018 The development of the new therapeutic drug which based on the structure of the virus activation enzyme: The new control method of the highly pathogenic infectious diseases.
2012 - 2015 Identification of novel proteases involved in the regulation of highly pathogenic avian influenza (HPAI) viruses infection
2009 - 2011 Medium chain fatty acid regulates uncoupling protein 3 expression in skeletal muscle

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Papers (49)：

Ayako Ohno, Nobuo Maita, Takanori Tabata, Hikaru Nagano, Kyohei Arita, Mariko Ariyoshi, Takayuki Uchida, Reiko Nakao, Anayt Ulla, Kosuke Sugiura, et al. Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza. Life Science Alliance. 2021. 4. 6. e202000849-e202000849
Motoko Oarada, Yuushi Okumura, Katsuya Hirasaka, Kosuke Sugiura, Nobuhiko Tachibana, Yoshinori Tsurusaki, Takeshi Nikawa. Dietary Sodium Nitrite Causes Similar Modifications to Splenic Inflammatory Gene Expression as a High-Fat Diet. Journal of nutritional science and vitaminology. 2021. 67. 6. 404-416
Takayuki Uchida, Yoshihiro Sakashita, Kanako Kitahata, Yui Yamashita, Chisato Tomida, Yuki Kimori, Akio Komatsu, Katsuya Hirasaka, Ayako Ohno, Reiko Nakao, et al. Reactive oxygen species upregulate expression of muscle atrophy-associated ubiquitin ligase Cbl-b in rat L6 skeletal muscle cells. American Journal of Physiology-Cell Physiology. 2018. 314. 6. C721-C731
Mayumi Takeya, Yuushi Okumura, Takeshi Nikawa. Modulation of cutaneous extracellular collagen contraction by phosphorylation status of p130Cas. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2017. 67. 5. 613-622
Katsuya Hirasaka, Edward M. Mills, Marie Haruna, Aki Bando, Chika Ikeda, Tomoki Abe, Shohei Kohno, Sara M. Nowinski, Cory U. Lago, Ken-ichi Akagi, et al. UCP3 is associated with Hax-1 in mitochondria in the presence of calcium ion. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2016. 472. 1. 108-113

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MISC (78)：

真板綾子, 真板宣夫, 奥村裕司, 永野ひかる, 有田恭平, 平坂勝也, 安倍知紀, 近藤茂忠, 二川健. 高病原性インフルエンザ感染に関わる宿主酵素MSPLと阻害ペプチドとの複合体構造. 日本栄養・食糧学会大会講演要旨集. 2017. 71回. 318-318
前田翼, 平坂勝也, 池田千佳, 春名真里江, 河野尚平, 安部知紀, 越智ありさ, 近藤茂忠, 真板綾子, 奥村裕司, et al. SIRT1発現上昇を介したイソフラボンによるサルコペニア抑制効果. 日本栄養・食糧学会大会講演要旨集. 2013. 67回. 149-149
平坂勝也, Mills Edward M, 池田千佳, 春名真里江, 前田翼, 安倍知紀, 宇都宮健郎, 越智ありさ, 河野尚平, 真板綾子, et al. サルコペニアにおけるミトコンドリア内カルシウム取り込み. 日本栄養・食糧学会大会講演要旨集. 2013. 67回. 238-238
永野ひかる, 近藤茂忠, 山岸直子, 数藤拓郎, 冨田知里, 坂井敦子, 安倍知紀, 宇都宮健郎, 越智ありさ, 池田千佳, et al. IRS-1遺伝子産物による骨格筋細胞の分化制御. 日本栄養・食糧学会大会講演要旨集. 2013. 67回. 180-180
後藤春樹, 越智ありさ, 中尾玲子, 北畑香菜子, 真板綾子, 平坂勝也, 奥村裕司, 近藤茂忠, 長野圭介, 川村知志, et al. 抗ユビキチン化ペプチドCblin(Cbl-b inhibitor)の高機能化および機能性食材の開発. アミノ酸研究. 2013. 6. 2. 165-165

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Education (2)：

1993 - 1997 The University of Tokushima Graduate School of Medicine
1987 - 1993 The University of Tokushima Faculty of Medicine

Professional career (1)：

Ph.D (The University of Tokushima)

Work history (11)：

2013/04 - 現在 Sagami Women's University Faculty of Nutritional Science Department of Nutrition and Health
2008 - - 徳島大学大学院ヘルスバイオサイエンス研究部准教授
2008 - - Associate Professor, The University of Tokushima
2007 - - 徳島大学疾患酵素学研究センター助教
1998 - 2000 米国スクリプス研究所研究員

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Association Membership(s) (11)：

日本栄養・食糧学会 , 日本病態プロテアーゼ学会 , 日本分子生物学会 , 日本生化学会 , 日本癌学会 , 日本アレルギー学会 , International Proteolysis Society , The Molecular Biology Society of Japan , The Japanese Cancer Association , The Japanese Biochemical Society , Japanese Society of Allergology

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