Yoshimura Tohru

2011 - 2012 Biochemical regulation of fermentation heat and its application towaste heat recovery power generation

2010 - 2012 Function and regulation of D-amino acid biosystem in eukaryote

2007 - 2009 Biosyntheses and molecular functions of novel biofactors, D-amino acids : from microorganisms to mammals

2004 - 2006 D-Amino acids in eucaryotic cells: physiological function and its molecular mechanism.

2004 - 2005 ABCタンパク質を制御する細胞浸透性ペプチドの開発

2003 - 2004 Screening of novel cold-adapted microorganisms and exploitation of their useful gene resources

2003 - 2004 Analysis of the mechanism of activation and co-translational insertion of an essential trace element, selenium, into polypeptide

2002 - 2003 Studies of physiological function of D-aspartate in eukaryotic cells : from yeasts to mammals

2001 - 2003 Construction and Characterization of Composite Biocatalysts

2000 - 2001 ファージを用いた水系中の微量物質の回収と除去

2000 - 2001 古細菌の蛋白質膜透過機構の解明と高度好塩古細菌を宿主とした膜蛋白質高生産系の構築

2000 - 2001 Isolation of novel psychrophilic microorganisms and exploitation of useful enzymes

2000 - 2000 高度好塩始原菌における細胞表層蛋白質生合成機構の解明と応用

1999 - 2000 Role of D-amino acid in adaptation of organisms to environmental change

1999 - 2000 Development of dehalogenases by molecular evolution technology : Application of production of useful materials and bioremediation of environments

1999 - 2000 Roles and specific functions of homologous enzymes involved in biogenesis of active-form sulfur and active-form selenium

1999 - 1999 ファージディスプレーを用いた進化分子工学による酵素機能の改変

1998 - 1999 細菌の多機能デハロゲナーゼを用いるダイオキシン分解系の開発

1998 - 1999 Physiolozical role and biosynthesis of D-aminoacids in eukanyote

1998 - 1999 Development and application of degradation system for polychlorinated dioxin

1998 - 1999 Investigation of halophilic microorganisms in salt lakes and development of novel halogenating and dehalogenating enzymes

1998 - 1998 ファージディスプレー法による機能性ヘム集合体のデザイン

1997 - 1998 Structural and functional analysis of microbial enzymes catalyzing defluorination and fluorination

1996 - 1997 Origine and Molecular Evolutionary Engineering of the Enzyme-Coenzyme Systems

1996 - 1996 2-ハロ酸デハロゲナーゼ反応の立体特異性を規定するタンパク質構造と触媒機構

1996 - 1996 アラニンラセマーゼのシャペロン様機能性ドメイン

1996 - 1996 ハロ酸の酵素的分解機構の解析とその環境浄化への応用

1995 - 1996 Screening of New Psychrophiles Producing Useful Enzymes

1995 - 1995 ハロ酸分解性微生物酵素の構造機能相関の解析、環境浄化への応用

1995 - 1995 酵素による立体選択的酸化と電極還元を組合せた新規キラル合成法開発

1994 - 1995 分断型アラニンラセマーゼの分子構造形成における細胞内マトリツクスの相互作用

1994 - 1995 Stereochemical Studies of the Structure, Function, and Molecular Evolution of Pyridoxal Enzymes

1994 - 1995 Biochemical and Molecular Biological Studies or Structure and Function of Glutamate Racemase

1994 - 1995 Application of Molecular Chaperone to Protein Engineering

1994 - 1995 Structure and Function of Enzymes Participating in Metabolism of D-Amino Acid of Bacterial Cell Walls and Development of their Specific Inhibitors

1994 - 1994 ハロ酸分解性微生物酵素の遺伝子工学的研究と環境浄化への応用

1994 - 1994 分断型アラニンラセマーゼの分子構造形成における細胞内マトリックスの相互作用

1994 - 1994 酵素による立体選択的酸化と電極還元を組合せた新規キラル合成法開発

1993 - 1994 Protein engineering studies of thermostable D-amino acid transaminase

1993 - 1993 ハロ酸分解系酵素の遺伝子工学的解析と応用

1992 - 1993 Comparative Studies on Structure and Function of Pyridoxal Dependent and Indepandent Amino Acid Racemases

1990 - 1991 Design of New Selenium Enzymes and Proteins, and Their Functions

1988 - 1990 Development of New Methods on Isotope-Labeling of Amino Acid and Vitamin with Microbial Enzymes

1986 - 1987 Total Consideration of the Feeding Process of Silkworm Larvae