Research keywords (3):
形態系基礎歯科学
, 機能系基礎歯科学
, Dental Biochemistry
Research theme for competitive and other funds (9):
2019 - 2023 Identification of cysteine peptidases that assure complete dipeptide production in periodontopathic bacteria
2019 - 2023 Novel modulating mechanisms of homeostasis by oral bacterial exopeptidases
2005 - 2007 Analysis of the effects of mucous protease inhibitor on periodontopathic bacteria and their proteases
2003 - 2006 Research on effectiveness of oral care on QOL of family caregivers.
2006 - シャペロンとストレス応答
2002 - 2004 Response of oral mucous epitherial cells for infection of pathogenic bacteria of periodontitis.
1991 - 1994 上皮増殖因子によるヒト顎下腺癌細胞株増殖機構の遺伝子レベルでの検索
1986 - 1988 ラット顎下腺アンドロゲンレセプターの分子構造に関する研究
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Papers (138):
Takayuki K. Nemoto, Haruka Nishimata, Kana Shirakura, Yuko Ohara-Nemoto. Potential elevation of exopeptidase activity of Glu-specific endopeptidase I/GluV8 mediated by hydrophobic P1′-position amino acid residue. Biochimie. 2024. 220. 99-106
Manami Nakasato-Suzuki, Yu Shimoyama, Yuko Ohara-Nemoto, Daisuke Sasaki, Takayuki K. Nemoto, Takashi Yaegashi. Exacerbation mechanism of type 2 diabetes mellitus by periodontopathic bacterial dipeptidyl-peptidases (DPPs). Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology). 2023. 65. 1. 1-8
Yu Shimoyama, Daisuke Sasaki, Yuko Ohara-Nemoto, Takayuki K. Nemoto, Manami Nakasato, Minoru Sasaki, Taichi Ishikawa. Immunoelectron microscopic analysis of dipeptidyl-peptidases and dipeptide transporter involved in nutrient acquisition in Porphyromonas gingivalis. Current Microbiology. 2023. 80. 106
Yuko Ohara-Nemoto, Yu Shimoyama, Toshio Ono, Mohammad Tanvir Sarwar, Manami Nakasato, Minoru Sasaki, Takayuki K. Nemoto. Expanded substrate specificity supported by P1′ and P2′ residues enables bacterial dipeptidyl-peptidase 7 to degrade bioactive peptides. Journal of Biological Chemistry. 2022. 298. 3. 101585-101585
Takayuki K. Nemoto, Yuko Ohara Nemoto. Dipeptidyl-peptidases: Key enzymes producing entry forms of extracellular proteins in asaccharolytic periodontopathic bacterium Porphyromonas gingivalis. Molecular Oral Microbiology. 2021. 36. 2. 145-156
- 1983 Tohoku University Graduate School, Division of Natural Science
- 1978 Tohoku University Faculty of Science Department of Biology
- 1978 Tohoku University Faculty of Science
Professional career (3):
Ph.D. (Tohoku University)
理学修士 (東北大学)
理学士 (東北大学)
Committee career (1):
2006 - 歯科基礎医学会 評議員
Awards (1):
1983 - 林女性自然科学者研究助成
Association Membership(s) (9):
アメリカ細菌学会
, 日本細菌学会
, 国際歯科研究学会
, 日本分子生物学会
, 歯科基礎医学会
, 日本生化学会
, American Sociaty for Microbiology
, International Association for Dental Research
, The Molecular Biology Society of Japan