Rchr
J-GLOBAL ID：200901002347213021
Update date: Jan. 09, 2020
TAKAHASHI Miho
タカハシ ミホ | TAKAHASHI Miho
Affiliation and department：
Job title：
Assistant Professor
Papers (18)：
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Takahashi M, Hattori T., Watanabe-Takahashi M., Nishikawa K., Nito M. Acuired Resistance to Shiga toxin-induced apoptosis by loss of CD77 expression in Human myelogenous leukemia cell line, THP-1. Biological and Pharmaceutical Bulletin. 2018. 41;9. 1475-1479
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Takahashi M, Watanabe-Takahashi M., Yamasaki S., Murata M., Kano F., Motoyama J., Yamate J., Omi J., Sato W., Ukai H., Shimasaki K., Ikegawa M., Tamura-Nakano M., Yanoshita R., Nishino Y., Miyazawa A., Natori Y., Toyama-Sorimachi N., Nishikawa K. Exosome-associated Shiga toxin2 is released from cells and causes severe toxicity in mice. Scientific Reports. 2018. 17;8. 10776
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Matsuoka K., Nishikawa K., Goshu Y., Koyama T., Hatano K., Matsushita T., Watanabe-Takahashi M., Natori Y., Terunuma D. Synthetic construction of sugar-amino acid hybrid polymers involving globotriaose or lactose and evaluation of their biological activities against Shiga toxins produced by Escherichia coli O157:H7. Bioorganic and Medicinal Chemistry. 2018. 26. 5792-5803
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Shimasaki K., Watanabe-Takahashi M., Umeda M., Funamoto S., Saito Y., Noguchi N., Kumagai K., hanada K., Tsukahara F., Maru Y., Shibata N., Naito M., Nishikawa K. The pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy. Genes to Cells. 2017
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Hattori T., Watanabe-Takahashi M., Shiina I., Ohashi Y., Dan S., Nishikawa K., Yamori T., Naito M. M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin. Genes to Cells. 2016. 21. 8. 901-906
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Patents (2)：
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CT阻害4価ペプチドおよびコレラ治療薬
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Stx2阻害4価ペプチドおよびこのStx2阻害4価ペプチドを含む治療薬
Lectures and oral presentations (6)：
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Exosome-associated Shiga toxin 2 is released from cells and causes severe toxicity in mice.
(VTEC2018 2018)
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RANK-TRAF6 signalを標的とした破骨細胞分化制御ペプチドの開発
(第91回日本生化学会 2018)
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新規CaMK2阻害ペプチドによるA型インフルエンザウイルス感染制御法の確立
(第91回日本生化学会 2018)
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酵素活性部位を標的とした新規ペプチド性Stx阻害薬の開発
(第22回腸管出血性大腸菌感染症研究会 2018)
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受容体結合部位を標的とした新規ペプチド性Subtilase cytotoxin阻害薬の開発
(第22回腸管出血性大腸菌感染症研究会 2018)
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Education (3)：
- - 2001 Hoshi University Faculty of Pharmaceutical Science
- - 2003 Hoshi University Graduate School, Division of Pharmaceutical Sciences
- - 2006 Hoshi University Graduate School, Division of Pharmaceutical Sciences
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