Kawashima Nobuyuki

2019 - 2022 Establishment of bacteriological examination method for diagnosing healing endodontic periodontal lesions

2016 - 2019 Investigation of the mechanism of onset of pulpitis developed from analysis of dendritic cell subsets in dental pulp

2015 - 2019 Cathepsin K inhibitor regulates inflammation and bone destruction in experimentally-induced rat periapical lesions.

2016 - 2018 Control of pulpal inflammation and hard tissue regeneration by miR-21, a modulator of cross-talk between inflammation and tissue regeneration

2013 - 2018 Establishment of dental pulp stem cell-isolation method and clinical approach of dental pulp tissue regeneration using dental pulp stem cells by signaling network control

2013 - 2016 Analyzing the unknown potential of dental pulp cells, and aiming to the new clinical development of regenerative therapy of dental pulp tissue

2010 - 2014 Resolution of the signaling networks involved in the pulp cell differentiation and its clinical application

2010 - 2012 Analysis of 3-D cultured dental pulp cells and osteoblasts and their clinical application

2009 - 2011 Shh signaling is related to Bmp signaling in ameloblast differentiation and tooth reconstruction

2007 - 2009 Effects of Notch Signaling on the Pulpal Cell Differentiation and the Horizon of Pulpal Regeneration by Regulation of Notch Signaling

2007 - 2008 Shh signaling is related to Bmp signaling in tooth reconstruction

2006 - 2008 The wound healing mechanisms and regenerative therapy in dental pulp and periapical tissues

2006 - 2007 歯髄組織の分化および機能にFGF18は重要である

2004 - 2006 Roles of Notch and Nov signaling on regeneration of hard tissues and a development of their clinical application

2004 - 2006 A study of the healing mechanisms of destructive periapical lesions and regenerative medicine for periapical bone defect

2003 - 2005 歯髄および歯根膜細胞の硬組織代謝における幹細胞としての可能性

2002 - 2003 Osteoblast Differentiation and Notch Signaling

2000 - 2002 ANALYSIS OF THE GENETIC REGULATORY NETWORK OF MINERALIZATION APPLYING MICROAARAY TECHNIQUE

2000 - 2002 Study on the influence of periapical lesions on systemic health

2000 - 2001 Exploring new candidate genes for pulpal mineralization using micro array system

1999 - 2001 Immune defense mechanisms of the dentin/pulp complex. An immunological and molecular biological analysis

1997 - 1999 Pulpal inflammation alters the physiological properties of intradental nerves in the adjacent teeth

1996 - 1996 ラット実験的根尖病変内サイトカイン発現に対するエストロジェン欠乏の影響

歯髄炎、根尖性歯周炎の免疫組織化学的研究

象牙芽細胞の分化メカニズム

歯髄炎、根尖性歯周炎の分子生物学的研究

Immunohistochemical Study on Pulpitis and Periapical Leions

Research on Calcification in the Pulp

Molecular Biological Study on Pulpitis and Periapical Leions