Hirata Masato

ヒラタマサト | Hirata Masato

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://d.fdcnet.ac.jp/

Research field (1)： Medical biochemistry

Research keywords (4)： Osteocalcin , Developmental Origin of Health and Disease , Metabolic syndrome , Cellular Biochemistry

Research theme for competitive and other funds (33)：

2024 - 2028 Investigation on obesity predisposition and its patho-physiological properties regulated by transgenerational epigenomic regulation
2020 - 2024 Studies on the effect of maternal uncarboxylated osteocalcin on the metabolic properties of next generation
2017 - 2021 Novel drug discovery for dislipidemia
2017 - 2020 Roles of osteocalcin for energy metabolism
2012 - 2017 Analysis of the functional interaction among bone, gut and energy metabolism with a special reference to gender difference

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Papers (208)：

Akiko Mizokami, Takahito Otani, Satoru Mukai, Masato Hirata. Roles of Nutrition-Sensing Receptor GPRC6A in Energy Metabolism and Oral Inflammatory Diseases. Current Oral Health Reports. 2024. 11. 4. 306-311
Takahito Otani, Akiko Mizokami, Hiroshi Takeuchi, Tetsuichiro Inai, Masato Hirata. The role of adhesion molecules in osteocalcin-induced effects on glucose and lipid metabolism in adipocytes. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2024. 1871. 4. 119701-119701
Tomoyo Kawakubo-Yasukochi, Yoshikazu Hayashi, Masato Hirata. Effects of Maternal Nutrition on Oral Health in Offspring. Current Oral Health Reports. 2023. 10. 3. 69-74
Mineyuki Mizuguchi, Takeshi Yokoyama, Takahito Otani, Shiori Kuribara, Yuko Nabeshima, Takayuki Obita, Masato Hirata, Keiichi Kawano. Structural and mutational analyses of decarboxylated osteocalcin provide insight into its adiponectin-inducing activity. FEBS Letters. 2023. 597. 11. 1479-1488
Jing Gao, Akiko Mizokami, Hiroshi Takeuchi, Aonan Li, Fei Huang, Haruki Nagano, Takashi Kanematsu, Eijiro Jimi, Masato Hirata. Phospholipase C-related but catalytically inactive protein acts as a positive regulator of insulin signalling in adipocytes. Journal of Cell Science. 2022. 135. 1

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MISC (33)：

溝上顕子, 安河内, 川久保, 友世, 平田雅人. オステオカルシンと美容. FOOD Style21. 2024. 28. 2. 22-25
溝上顕子, 安河内(川久保)友世, 大谷崇仁, 平田雅人. オステオカルシンのホルモン作用. 糖尿病・内分泌代謝科. 2022. 54. 3. 259-266
平田雅人. 骨と臓器のコミュニケーション〜オステオカルシンの研究から〜. FOOD Style 21. 2021. 25. 9. 8-11
溝上顕子, 安河内(川久保)友世, 平田雅人. 骨が支える健康長寿-若返りホルモン「オステオカルシン」を中心に. FOOD Style 21. 2020. 24. 7. 37-39
平田雅人. 骨の作り出すメッセージ物質が免疫力アップ、記憶力アップを促し、若返り効果を生む. 人体驚異のメカニズム. 2018. 68-70

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Books (26)：

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Lectures and oral presentations (80)：

Amelioration of cell number and metabolic features of adipocytes by osteocalcin
(Journal of Oral Biosciences Supplement (Web) 2020)
Functional modulation of myotubes by osteocalcin
(JOURNAL OF PHARMACOLOGICAL SCIENCES 2015)
Acceleration of bone regeneration by local application of lithium: Wnt signal-mediated osteoblastogenesis and Wnt signal-independent suppression of osteoclastogenesis (vol 90, pg 397, 2014)
(BIOCHEMICAL PHARMACOLOGY 2014)
Altered intracellular trafficking of EGFR by extracellular glucose concentration in squamous carcinoma cells
(FASEB JOURNAL 2014)
Scorpion toxin modulates P2X receptor activation in rat cerebral artery myocyte
(JOURNAL OF PHARMACOLOGICAL SCIENCES 2014)

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Education (2)：

Professional career (1)：

Work history (9)：

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Committee career (3)：

Awards (3)：

Association Membership(s) (3)：

歯科基礎医学会 , 薬理学会 , 生化学会

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