Research keywords (6)：
hepatitis C virus
, 抗ウイルス剤
, 肝炎
, Carcinogenesis
, Cancer
, Virus
Research theme for competitive and other funds (33)：
2010 - 2016 Infection/inflammation-assisted acceleration of the carcinogenic spiral and its alteration though vector conversion of the host response to tumors
2010 - 2015 Prevention of cancer development by hepatitis C virus
2010 - 2014 The role of lipid metabolism on HCV proliferation
1983 - 2010 ヒトT細胞白血病ウィルスによる発がん機構 肝炎ウィルスによる肝発がん
1983 - 2010 Molecular mechanism of carcinogenesis of human T-cell leukemia virus Molecular mechanism of hepatocarcinogenesis by hepatic viruses
2008 - 2009 Roles of lipid in HCV production
2005 - 2009 Development of preventive measures of liver failures caused by HCV infection by clarification of the mechanisms of liver diseases
2004 - 2009 Genetic and Epigenetic Dysregulation in Cancer
2007 - 2008 Trial for the novel therapy of chronic hepatitis C by using platform of the RNAi machinery
2007 - 2007 インターフェロンに抵抗性を示すC型肝炎ウイルスの複製戦略の解明
2004 - 2005 The roles of Tax encoded by HTLV on cell proliferation
2000 - 2004 Preventive measure of the development of hepatocellular carcinoma by hepatitis C virus infection
2003 - 2003 RNAウイルス研究の新展開
2002 - 2003 Transcriptional Regulation and Cell Immortalization in human T-cell leukemia virus type 1 encoded by Tax
2001 - 2002 On the development of the system to screen new anti-HCV drugs
2000 - 2001 Clarification of mechanism of HTLV-1 Tax protein on cell immortalization.
1999 - 1999 RNAウイルス研究の最前線
1998 - 1999 Clarification of reguratory mechanism of cell proliferation by HTLV-1.
1998 - 1999 Clarification of molecular mechanisims of hepatocellular carcinoma caused by hepatitis virus infection.
1998 - 1998 RNAウイルス研究の新展開
1994 - 1994 肝炎ウイルス制圧へ向けての包括的研究
1993 - 1993 遺伝子工学的アプローチによるウイルス性肝病態進展の予測と治療法の開発
1991 - 1993 肝炎ウイルスと肝発がん
1991 - 1992 肝炎ウイルスと肝発がん
1991 - 1991 肝炎ウイルスと肝発がん
1990 - 1990 成人T細胞白血病と病因ウイルス
1988 - 1990 AIDSウィルス合成ワクチンのための総合的方法論を目指した試験的研究
1988 - 1990 Cooperation and Information Exchange with European Countries
1989 - 1989 B型肝炎ウイルスの増殖・組込みと肝癌発生との関連
1988 - 1988 Trans-acting遺伝子の機能と細胞のがん化
1987 - 1987 Transーacting遺伝子の機能と細胞のがん化
1986 - 1986 ヒト白血病ウイルスプロウイルスDNAの試験管内における転写系の確立
1985 - 1985 ヒト白血病ウイルスに存在する遺伝子(X)の構造と発現
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Papers (294)：
Hironori Nishitsuji, Yui Naito, Yuuna Murakami, Masaya Sugiyama, Masashi Mizokami, Ikuo Shoji, Takayuki Murata, Kunitada Shimotohno. Identification of glycogen synthase kinase 3alpha/beta as a host factor required for HBV transcription using high-throughput screening. Hepatology (Baltimore, Md.). 2025
Amrizal Muchtar, Daichi Onomura, Dan Ding, Hironori Nishitsuji, Kunitada Shimotohno, Shunpei Okada, Keiji Ueda, Koichi Watashi, Takaji Wakita, Kei Iida, et al. MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX. Frontiers in Microbiology. 2025. 15
Asako Murayama, Hitomi Igarashi, Norie Yamada, Hussein Hassan Aly, Natalia Molchanova, Jennifer S Lin, Hironori Nishitsuji, Kunitada Shimotohno, Masamichi Muramatsu, Annelise E Barron, et al. Antiviral effect of peptoids on hepatitis B virus infection in cell culture. Antiviral research. 2024. 223. 105821-105821
Takayuki Murata, Satoko Iwahori, Yusuke Okuno, Hironori Nishitsuji, Yusuke Yanagi, Koichi Watashi, Takaji Wakita, Hiroshi Kimura, Kunitada Shimotohno. N6-methyladenosine Modification of Hepatitis B Virus RNA in the Coding Region of HBx. International journal of molecular sciences. 2023. 24. 3
- 1967 Tohoku University Faculty of Science Department of Chemistry
- 1967 Tohoku University Faculty of Science, Department of Chemistry
Professional career (1)：
Doctor of Pharmaceutical Sciences (Hokkaido University)
Work history (6)：
2011/11 - 現在 National Center for Global Health and Medicine Research Center for Hepatitis and Immunology Project Chief
2007/04 - 2011/10 Chiba Institute of Technology Research Institute professor
1996/09 - 2006/03 京都大学ウィルス研教授
1985 - 1996 国立がんセンター研究所部長
1983 - 1985 国立がんセンター研究所室長
1972 - 1983 National Institute of Genetics
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Committee career (5)：
1990 - 日本生化学会 評議員
1990 - The Japanese Biochemical Society Councilor
1987 - 日本癌学会 評議員
1987 - The Japanese Cancer Association Councilor
日本ウイルス学会 会員,第51回日本ウイルス学会学術集会会長(2003)
Awards (4)：
2016/02 - Princess Takamatsu Cancer Research Fund Princess Takamatsu Cancer Research Fund Prizes
2006/09 - Japanese Cancer Association Yoshida Tomizo prie
1997 - 野口英世医学賞
1985 - 日本遺伝学会奨励賞
Association Membership(s) (8)：
日本肝臓学会
, 日本ウイルス学会
, 日本分子生物学会
, 日本生化学会
, 日本癌学会
, The Molecular Biology Society of Japan
, The Japanese Cancer Association
, The Japanese Biochemical Society
