Shibanuma Motoko

シバヌマモトコ | Shibanuma Motoko

Affiliation and department：
Job title： Professor

Research field (3)： Pharmacology , Pharmaceuticals - health and biochemistry , Cell biology

Research keywords (4)：生物系薬学 , 細胞生物学 , Biopharmcology , Cell Biology

Research theme for competitive and other funds (6)：

2009 - ミトコンドリア機能変化と細胞悪性化、幹細胞形質発現との関連
2008 - Mitochondrial respiratory activity and malignant conversion of cells
上皮-間充織細胞転換(epithelial mesenchymal transition)を含む細胞の悪性化形質に特異的なTGFβ1シグナルの解析(TGFβシグナルとしての活性酸素種の役割)
細胞接着斑-核両局在性蛋白質HIC-5複合体による細胞増殖の足場依存性制御機構と癌の悪性化(転移)に関する研究(細胞内レドックスとの関わり)
Analysis on molecular mechanism of epithelial mesenchymal transition induced by reactive oxygen species and TGFβ1 "a role of reactive oxygen species in TGFβ1 signaling"

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Papers (80)：

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MISC (14)：

丸山剛, 斉藤光次, 日暮大渡, 石川文博, 河野葉子, 森一憲, 柴沼質子. HMGA2/IGFBP1/AKT経路によるP27KIP1分解機構の制御と癌治療標的としての意義(HMGA2 drives IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein in mitochondria-deficient cancer cells). 日本癌学会総会記事. 2022. 81回. P-1197
福原潔, 森一憲, 沖山佳生, 三澤隆史, 水野美麗, 出水庸介, 柴沼質子, 大野彰子. Rationally Designed Peptide Modulators of Amyloid β Toxicity in Alzheimer’s Disease. 日本農芸化学会大会講演要旨集(Web). 2022. 2022
水野美麗, 森一憲, 三澤隆史, 高木孝士, 出水庸介, 柴沼質子, 福原潔. アミロイドβを創薬標的としたシリビニン誘導体の開発. メディシナルケミストリーシンポジウム講演要旨集. 2019. 37th
Mirei Mizuno, Kazunori Mori, Ikuo Nakanishi, Ken-ichiro Matsumoto, Motoko Shibanuma, Kiyoshi Fukuhara. Design and synthesis ofproanthocyanidin derivatives as an inhibitor of amyloid beta aggregation. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 2018. 256
MORI KAZUNORI, NOSE KIYOSHI, SHIBANUMA MOTOKO. Involvement of cyclin D1 in anchorage-independent survival. 2007. 26. 1. 53-53

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Books (2)：

Biological roles of H2O2 produced by treatment with TGFb1 in mouse osteoblastic cells. In Frontiers on reactive oxygen species in biology and medicine(jointly worked)
Excerpta Medica 1994
Involvement of hydrogen peroxide in the actions of TGFb1(jointly worked)
"Oxidateve Stress, Cell Activation and Viral Infection" 1994

Education (4)：

Professional career (1)：

Work history (8)：

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Awards (2)：

Association Membership(s) (3)：

日本組織培養学会(評議委員) , 日本分子生物学会 , 日本癌学会(評議委員)

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