J-GLOBAL ID:200901003739629451   Update date: Jan. 10, 2020


ツジノ イチロウ | TSUJINO Ichiro
Affiliation and department:
Job title: Associate Professor
Other affiliations (2):
Research field  (2): General medical chemistry ,  Respiratory organ internal medicine
Research keywords  (5): 抗がん剤 ,  薬剤耐性 ,  がん微小環境 ,  pERK ,  標的分子と分子標的薬
Papers (18):
  • Tsujino I, Miyagi K, Sampson RW, Sieber F. Potentiation of the antitumor effect of Merocyanine 540-mediated photodynamic therapy by amifostine and amphotericin B. Photochemistry and Photobiology. 2006. 82. 2. 458-65
  • Tsujino I, Anderson GS, Sieber F. Postirradiation hyperthermia selectively potentiates the merocyanine 540-sensitized photoinactivation of small cell lung cancer cells. Photochemistry and Photobiology. 2001. 73. 2. 191 - 198
  • Tsujino I, Sieber F. Genetic variability in the response of normal murine hematopoietic progenitor cells to extracorporeal photochemotherapy. Photochemistry and Photobiology. 2000. 72. 6. 810 - 814
  • Tsujino I, Yamazaki T, Masutani M, Sawada U, Horie T. Effect of Tween-80 on cell killing by etoposide in human lung adenocarcinoma cells. Cancer Chemotherapy and Pharmacology. 1999. 43. 1 -2. 29 - 34
  • 須金紀雄、辻野一郎、山崎哲男、高橋典明、赤柴恒人、澤田海彦、堀江. 肺腺癌細胞におけるCremophor ELによるetoposide(VP16)の殺細胞効果の増強についての検討. 肺癌. 2003. 43. 4. 307 - 313
MISC (7):
  • Tsujino I, Nakanishi Y, Hiranuma H, Shimizu T, Hirotani Y, Ohni S, Ouchi Y, Takahashi N, Nemoto N, Hashimoto S. Increased phosphorylation of ERK1/2 is associated with worse chemotherapeutic outcome and a poor prognosis in advanced lung adenocarcinoma. Medical Mollecular Morphology. Medical Mollecular Morphology. 2015
  • Sato M, Tsujino I, Fukunaga M, Mizumura K, Gon Y, Takahashi N, Hashimoto S. Cyclosporine A induces apoptosis of human lung adenocaricinoma cells via caspase-dependent pathway. Anticancer Research. 2011 Jun ; 31(6) : 2129-2134. Anticancer Research. 2011. 31(6) : 2129-2134
  • Nakanishi Y, Shimizu T, Tsujino I, Obana Y, Seki T, Fuchinoue F, Ohni S, Oinuma T, Kusumi Y, Yamada T, Takahashi N, Hashimoto S, Nemoto N. Semi-nested real-time reverse transcription PCR methods for the successful quantit. of cytokeratin mRNA expression levels for the subtyping of non-small-cell lung carcinoma using paraffin-embedded and microdissected lung biopsy specimens. Acta Histochemica et Cytochemica. 2013. 30;46(2):85-96
  • Shimizu T, Nakanishi Y, Nakagawa Y, Tsujino I, Takahashi N, Nemoto N,Hashimoto S. Association between expression of thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase and efficacy of pemetrexed in advanced non-small cell lung cancer. Anticancer Reserch. 2012. 32(10):4589-96,
  • Daziano JP, Günther WH, Krieg M, Tsujino I, Miyagi K, Anderson GS, Sampson RW, Ostrowski MD, Muir SA, Bula RJ, Sieber F. Photochemically generated elemental Selenium forms conjugates with Serum proteins that are preferentially cytotoxic to leukemia and selected solid tumor cells. Photochemistry and Photobiology. 2012. 88(2): 448-60
Lectures and oral presentations  (14):
  • Genetic Variability in the Response of Normal Murine Hematopoietic Progenitor Cells to Extracorporeal Photochemotherapy.
    (29th Annual Meeting of the International Society for Experimental Hematology, 2000)
  • III期非小細胞肺癌に対するシスプラチン、ビノレルビン併用化学療法と同時 胸部照射の臨床第II相試験
    (第42回日本肺癌学会 2001)
  • 肺腺癌細胞におけるTween-80によるシクロスポリンAの殺細胞効果増強に関する検討
    (第49回日本肺癌学会総会 2008)
  • 進行非小細胞肺癌に対する二次療法としてのゲムシタビン+ビノレルビン併用療法の有用性について
    (第48回日本呼吸器学会総会 2008)
  • 高齢者肺癌の治療おける併存合併症の影響について
    (第49回日本肺癌学会総会 2009)
Education (1):
  • - 1990 Nihon Unversity School of Medicine
Professional career (1):
  • PhD (Nihon Unversity)
Awards (1):
  • 2018/05/19 - 日本大学医師会 日本大学医学部・日本大学医師会 学術奨励賞 非小細胞肺癌におけるMAP kinase 活性度と治療効果および予後の検討 (特別講演)
Association Membership(s) (4):
日本呼吸器内視鏡学会 ,  日本呼吸器学会 ,  日本内科学会 ,  日本肺癌学会
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