Rchr
J-GLOBAL ID:200901004225991573   Update date: Apr. 29, 2024

Chuman Yoshiro

チュウマン ヨシロウ | Chuman Yoshiro
Affiliation and department:
Other affiliations (4):
  • Niigata University
  • Niigata University  Institute for Research Promotion 
  • Niigata University  Big data activation research center 
  • Ministry of Education,Culture,Sports,Science and Technology
Homepage URL  (2): http://chem.sc.niigata-u.ac.jp/~chuman/http://barato.sci.hokudai.ac.jp/~biochem/
Research field  (5): Tumor diagnostics and therapeutics ,  Functional biochemistry ,  Biochemistry ,  Molecular biochemistry ,  Green/sustainable/environmental chemistry
Research keywords  (15): 刺激応答性分子 ,  生化学 ,  バイオセンサー ,  バイオマテリアル ,  抗癌剤 ,  抗体 ,  cancer ,  aptamer ,  peptide ,  phosphorylation ,  phosphatase ,  生物化学 ,  Functional biochemistry ,  Structural biochemistry ,  Biochemistry
Research theme for competitive and other funds  (32):
  • 2024 - 2025 パレコウイルスA3感染症の克服に必要な基盤研究技術の創出
  • 2024 - 2025 転移性肺がんを標的としたDDS機能を内包する細胞膜透過型ポスト抗体薬の開発
  • 2022 - 2025 Functional optimization and establishment of comprehensive evaluation of membrane-permeable aptamers for drug development using AI technology
  • 2022 - 2024 ナノバブル化ネオマクロライドを用いたワクチン副反応の予防薬の開発研究
  • 2020 - 2024 薬剤耐性肺炎球菌のin vivo MS解析とキューブ型DNA抗菌薬の開発研究
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Papers (56):
  • Tamaki Kobayashi, Kazuki Yamazaki, Junki Shinada, Masataka Mizunuma, Kazuhiro Furukawa, Yoshiro Chuman. Identification of Inhibitors of the Disease-Associated Protein Phosphatase Scp1 Using Antibody Mimetic Molecules. Int. J. Mol. Sci. 2024. 25. 7. 3737-3737
  • Masataka Mizunuma, Mirai Suzuki, Tamaki Kobayashi, Yuki Hara, Atsushi Kaneko, Kazuhiro Furukawa, Yoshiro Chuman. Development of Mn2+-Specific Biosensor Using G-Quadruplex-Based DNA. Int. J. Mol. Sci. 2023. 24. 14. 11556-11556
  • Rui Kamada, Hiromitsu Miyazaki, Jose Isagani Janairo, Yoshiro Chuman, Kazuyasu Sakaguchi. Bilayer Hydrogel Composed of Elastin-Mimetic Polypeptides as a Bio-Actuator with Bidirectional and Reversible Bending Behaviors. Molecules. 2023. 28. 13. 5274
  • Megumi Ikeura, Hiroto Tashiro, Yuka Yamagata, Hikaru Saito, Tamaki Kobayashi, Masataka Mizunuma, Kazuki Yamazaki, Keisuke Baba, Kazuhiro Furukawa, Yoshiro Chuman. Development of Antibody-like Proteins Targeting the Oncogenic Ser/Thr Protein Phosphatase PPM1D. Processes. 2022. 10. 8. 1501-1501
  • Masataka Mizunuma, Atsushi Kaneko, Shunta Imai, Kazuhiro Furukawa, Yoshiro Chuman. Methods for Identification of Substrates/Inhibitors of FCP/SCP Type Protein Ser/Thr Phosphatases. Processes. 2020. 8. 12. 1598-1598
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MISC (81):
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Patents (7):
  • 核酸アプタマー組成物、抗がん剤及びがん治療キット
  • 核酸アプタマー及びその使用
  • 膜透過型核酸アプタマー
  • 細胞内分子を標的とした細胞膜透過型核酸アプタマー
  • Monoclonal antibody specifically recognizing modification site after translation of p53 and kit for assaying modification site containing the same
more...
Books (11):
  • 光刺激応答性核酸の現状と新規核酸創薬モダリティへの応用
    Precision Medicine 2022
  • Trends and development of stimuli-responsive oligonucleotide drugs in spatiotemporally controlled manner
    2021
  • Application of Mn2+-specific Biosensor Based on 2. G-quadruplex DNA Aptamer
    The Japanese Peptide Society, Peptide Sci. 2021, 135-136 2021
  • アプタマー創薬の現状と細胞膜 自動透過性DNAアプタマーの開発
    月刊「細胞」 2020
  • 発がん関連酵素に対するDNAアプタマーを用いた新規阻害剤開発と応用
    月刊「細胞」 2019
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Lectures and oral presentations  (47):
  • DNA四重鎖G4構造を母体とした新規機能性ツール:IRDAptamerの開発と応用
    (第5回アプタマー研究会 2024)
  • Development of Scp1 protein phosphatase inhibitors from new drug platform IRDAptamer library
    (The 5th Japan-Taiwan Bilateral Conference on Protein Phosphatase 2024)
  • New drug modality: IRDAptamers
    (Biological Chemistry Symposium 2023 2023)
  • 細胞内を標的可能な新規創薬プラットホームの開発 刺激応答性DNAアプタマー: IRDAptamer
    (エッセンスフォーラム2023 2023)
  • 多様な疾患に適応可能なキューブ型DNAアプタマー IRDAptamer
    (2023年度 第1回BVA定例会 2023)
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Education (3):
  • 2001 - Kyushu University Graduate School of Sciences
  • 1998 - Kyushu University
  • 1996 - Kyushu University
Professional career (1):
  • 博士(理学) (九州大学)
Work history (11):
  • 2021/09 - 現在 Niigata University Institute for Research Promotion
  • 2017/04 - 現在 Niigata University Faculty of Science, Department of Science
  • 2013/11 - 2017/03 Niigata University Faculty of Science, Department of Chemistry
  • 2007/04 - 2013/10 Hokkaido University Faculty of Science
  • 2001/11 - 2007/03 Hokkaido University
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Committee career (9):
  • 2019 - 現在 新潟生化学懇話会 幹事
  • 2019 - 現在 文部科学省 専門調査員
  • 2019 - 現在 Bentham Science publishers Bentham Ambassador
  • 2017 - 現在 日本化学会 関東支部新潟地域懇談会事務局
  • 2016 - 現在 N-hybrid 世話人
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Awards (2):
  • 2010 - 2010年度(第18回) JB論文賞
  • 2002 - Fellows Award for Research Excellence (FARE) 2003(National Institutes of Health)
Association Membership(s) (8):
Nucleic Acids Therapeutics Society of Japan ,  Japanese Association for Protein Phophatase Research ,  The Japanese Biochemical Society ,  The Chemical Society of Japan ,  The Japnase Peptide Society ,  日本核酸化学会 ,  Japan Cancer Association ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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