Rchr
J-GLOBAL ID：200901004499684642
Update date: Jun. 08, 2020
HORINOUCHI Masae
ホリノウチ マサエ | HORINOUCHI Masae
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Affiliation and department：
RIKEN Wako Institute, Discovery Research Institute
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Detailed information
Research field (1)：
Applied microbiology
Research keywords (5)：
テストステロン
, コール酸
, 分解
, ステロイド
, 細菌
Research theme for competitive and other funds (1)：
1999 - 細菌のステロイド分解の解明
Papers (11)：
Masae Horinouchi, Toshiaki Hayashi, Hiroyuki Koshino, Michal Malon, Hiroshi Hirota, Toshiaki Kudo. Identification of 9 alpha-Hydroxy-17-Oxo-1,2,3,4,10,19-Hexanorandrostan-5-Oic Acid in Steroid Degradation by Comamonas testosteroni TA441 and Its Conversion to the Corresponding 6-En-5-Oyl Coenzyme A (CoA) Involving Open Reading Frame 28 (ORF28)- and ORF30-Encoded Acyl-CoA Dehydrogenases. JOURNAL OF BACTERIOLOGY. 2014. 196. 20. 3598-3608
Masae Horinouchi, Toshiaki Hayashi, Hiroyuki Koshino, Michal Malon, Hiroshi Hirota, Toshiaki Kudo. Identification of 9 alpha-hydroxy-17-oxo-1,2,3,4,10,19-hexanorandrost-6-en-5-oic acid and beta-oxidation products of the C-17 side chain in cholic acid degradation by Comamonas testosteroni TA441. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2014. 143. 306-322
Masae Horinouchi, Toshiaki Hayashi, Toshiaki Kudo. Steroid degradation in Comamonas testosteroni. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2012. 129. 1-2. 4-14
Masae Horinouchi, Tomokazu Kurita, Toshiaki Hayashi, Toshiaki Kudo. Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Delta 4(5)-isomerase and 3 alpha- and 3 beta-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2010. 122. 4. 253-263
Masae Horinouchi, Toshiaki Hayashi, Hiroyuki Koshino, Michal Malon, Takako Yamamoto, Toshiaki Kudo. Identification of genes involved in inversion of stereochemistry of a C-12 hydroxyl group in the catabolism of cholic acid by Comamonas testosteroni TA441. JOURNAL OF BACTERIOLOGY. 2008. 190. 16. 5545-5554
ｍore...
MISC (7)：
Masae Horinouchi, Toshiaki Hayashi, Hiroyuki Koshino, Toshiaki Kudo. ORF18-disrupted mutant of Comamonas testosteroni TA441 accumulates significant amounts of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid and its derivatives after incubation with steroids. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2006. 101. 1. 78-84
M Horinouchi, T Hayashi, H Koshino, T Kurita, T Kudo. Identification of 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oic acid, 4-hydroxy-2-oxohexanoic acid, and 2-hydroxyhexa-2,4-dienoic acid and related enzymes involved in testosterone degradation in Comamonas testosteroni TA441. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2005. 71. 9. 5275-5281
M Horinouchi, T Kurita, T Yamamoto, E Hatori, T Hayashi, T Kudo. Steroid degradation gene cluster of Comamonas testosteroni consisting of 18 putative genes from meta-cleavage enzyme gene tesB to regulator gene tesR. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2004. 324. 2. 597-604
M Horinouchi, T Hayashi, T Kudo. The genes encoding the hydroxylase of 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione in steroid degradation in Comamonas testosteroni TA441. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2004. 92. 3. 143-154
M Horinouchi, T Hayashi, T Yamamoto, T Kudo. A new bacterial steroid degradation gene cluster in Comamonas testosteroni TA441 which consists of aromatic-compound degradation genes for seco-steroids and 3-ketosteroid dehydrogenase genes. APPLIED AND ENVIRONMENTAL MICROBIOLOGY. 2003. 69. 8. 4421-4430
ｍore...
Education (1)：
- 1999 The University of Tokyo
Professional career (1)：
博士(農学) (東京大学大学院)
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