Research field (3):
Applied biochemistry
, Functional biochemistry
, Biochemistry
Research keywords (8):
金属タンパク質
, タンパク質工学
, 分子生物学
, 生化学
, Metalloproteins
, Protein engineering
, Molecular Biology
, Biochemistry
Research theme for competitive and other funds (22):
2022 - 2025 Control of electron transfer reaction between enzyme and electrode by site-specific addition of hydrophilic polymer
2018 - 2021 Elucidation of the oxygen reduction mechanism of multicopper oxidase by structural analysis of reaction intermediates and its application.
2015 - 2018 Investigation and application of highly selective bromination reaction mechanism of biosynthetic enzyme of Tyrian purple, an ancient pigment
2014 - 2017 Study on Dioxygen Reduction Mechanism by Multicopper Oxidases and Application of Function Modulated Mutants as Electrode Catalyst
2011 - 2013 Research and development of the highly-active cathodic enzyme necessary for the practical use of the bio-fuel cell
2009 - 2010 金属タンパク質をホロ化する金属シャペロンタンパク質の開発
2007 - 2009 Studies on the molecular evolution process of proton pumps by mutations of the multiheme-containing nitric oxide reductase
2004 - 2005 一酸化窒素還元から酸素還元への変換による呼吸酵素の分子進化
2004 - 2005 MEASUREMENT OF ELECTRIC FIELD GRADIENT AT THE METAL SITES IN PROTEINS
2002 - 2003 一酸化窒素還元酵素の活性中心構造と触媒反応機構の解明
1999 - 2001 Studies on Multi-nuclear Copper Enzymes and their Model Complexes
1999 - 2000 銅型亜硝酸還元酵素の構造と触媒反応機構および電子伝達機構に関する研究
1999 - 1999 硝酸呼吸系に含まれる銅タンパク質の構造と機能の研究
1998 - 1998 硝酸呼吸系に含まれる銅タンパク質の構造と機能の研究
1997 - 1997 硝酸呼吸系に含まれる銅タンパク質の構造と機能の研究
1997 - 金属タンパク質のタンパク質工学的機能改変
1997 - Protein engineering of metalloproteins
1996 - 1996 硝酸呼吸系に含まれる銅タンパク質の構造と機能の研究
1995 - 1996 Bioinorganic Chemical Study on Structure and Function of Cu-containing Nitrite Reductase
1995 - 1995 タンパク質工学によるアミノ酸脱水素酵素の基質特異性の変換
1995 - マルチメタル酵素の構造と機能に関する研究
1995 - Studies on structures and functions of multi-metal containing proteins
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Papers (35):
Ryo Kutsukawa, Riki Imaizumi, Miki Suenaga-Hiromori, Kohei Takeshita, Naoki Sakai, Shuto Misawa, Masaki Yamamoto, Haruhiko Yamaguchi, Yukino Miyagi-Inoue, Toshiyuki Waki, et al. Structure-based engineering of a short-chain cis-prenyltransferase to biosynthesize nonnatural all-cis-polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate product chain-length determination. The FEBS journal. 2022. 289. 15. 4602-4621
Riki Imaizumi, Ryo Mameda, Kohei Takeshita, Hiroki Kubo, Naoki Sakai, Shun Nakata, Seiji Takahashi, Kunishige Kataoka, Masaki Yamamoto, Toru Nakayama, et al. Crystal structure of chalcone synthase, a key enzyme for isoflavonoid biosynthesis in soybean. Proteins. 2020
Masahiro Miyata, Yuki Kitazumi, Osamu Shirai, Kunishige Kataoka, Kenji Kano. Diffusion-limited biosensing of dissolved oxygen by direct electron transfer-type bioelectrocatalysis of multi-copper oxidases immobilized on porous gold microelectrodes. JOURNAL OF ELECTROANALYTICAL CHEMISTRY. 2020. 860
Taiki Adachi, Yuki Kitazumi, Osamu Shirai, Tenta Kawano, Kunishige Kataoka, Kenji Kano. Effects of Elimination of a Helix Regions on Direct Electron Transfer-type Bioelectrocatalytic Properties of Copper Efflux Oxidase. ELECTROCHEMISTRY. 2020. 88. 3. 185-189
Takeshi Sakurai, Takao Kajikawa, Kunishige Kataoka. Dual effect of the mutational modification of the proton transfer pathway and a type I Cu ligand on properties and function of the trinuclear copper center in CueO. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S849-S849
Y. Higuchi, M. Akter, C. Inoue, Y. Shomura, N. Shibata, K. Inaka, K. Kataoka, T. Sakurai, K. Komori. Preparation of single crystals of Multicopper oxidases for neutron diffraction study. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY. 2014. 19. S324-S324
Strategic Development of PEFC Technologies for Practical Application. Development of Technology for Next-generation Fuel Cells. Research and Development of Novel Anode Catalysts Based on Multi-copper Oxidases
2005 -
Education (4):
- 1993 Kyoto University
- 1993 Kyoto University Graduate School, Division of Agriculture
- 1988 University of Tsukuba
- 1988 University of Tsukuba Second Cluster of College
Professional career (2):
農学修士 (京都大学)
博士(理学) (大阪大学)
Work history (11):
2011 - 現在 : 金沢大学 教授
2005 - 2011 : 金沢大学 准教授
2001 - 2005 : 金沢大学 講師
2001 - 2005 : Kanazawa University
2005 - -: Kanazawa University
1996 - 2001 : 大阪大学 助手
1996 - 2001 : Osaka University
1995 - 1996 : 大阪大学 助手
1995 - 1996 : Osaka University
1993 - 1994 : 大阪大学 教務職員
1993 - 1994 : Osaka University
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Committee career (3):
2018 - 2019 : 日本生化学会 北陸支部幹事
2005 - 2007 : The Japanese Biochemical Society
2005 - 2007 : 日本生化学会 北陸支部会幹事
Awards (7):
2006 - 平成18年度 長瀬科学技術振興財団研究助成
2006 - Nagase Science and Technology Foundation
2004 - 平成16年度 第11回京都市・山本文二郎漆科学研究助成
2001 - 平成13年度 金子・成田研究奨励金
1999 - 平成11年度 短期研究助成金
1995 - JB論文賞
1995 - JB Award
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Association Membership(s) (8):
生物無機化学国際学会
, 日本農芸化学会
, 日本生化学会
, The Society of Biological Inorganic Chemistry
, and Agrochemistry
, Biotechnology
, Japan Society for Bioscience
, The Japanese Biochemical Society