2016 - 2018 Elucidation of the molecular determinants of neonicotinoid toxicity
2013 - 2016 Elucidation of molecular mechanism of pyrethrin biosynthesis by a GDSL lipase and its application to creation of insect resistant plants
Papers (60)：
Mayuka Takebayashi, Sumito Mori, Ryo Ito, Koichi Takayama, Hisanori Ojima, Miyu Takeuchi, Hiyori Takahashi, Niina Yamamoto, Runa Egawa, Yuki Kimura, et al. Impact of a worker bee thoracic ganglion RIC-3 variant on the actions of acetylcholine and neonicotinoids on nicotinic receptors in Apis mellifera. Pest management science. 2024
Makoto Ihara, Noriko Tsuchida, Marina Sumida, Tomoki Himiyama, Takashi Kitayama, Norifumi Shirasaka, Yasuhisa Fukuta. Crystal Structure of the Native Chromoprotein from Pleurotus salmoneostramineus Provides Insights into the Pigmentation Mechanism. Journal of agricultural and food chemistry. 2024. 72. 31. 17626-17632
Ryo Ito, Masaki Kamiya, Koichi Takayama, Sumito Mori, Rei Matsumoto, Mayuka Takebayashi, Hisanori Ojima, Shota Fujimura, Haruki Yamamoto, Masayuki Ohno, et al. Unravelling nicotinic receptor and ligand features underlying neonicotinoid knockdown actions on the malaria vector mosquito Anopheles gambiae. Open Biology. 2024. 14. 7
Keisuke Nishikawa, Yosuke Ono, Sumito Mori, Koichi Takayama, Makoto Ihara, Kazuhiko Matsuda, Yoshiki Morimoto. Divergent Nine-Step Syntheses of Perhydrohistrionicotoxin Analogs and Their Inhibition Activity Toward Chicken α4β2-Neuronal Nicotinic Acetylcholine Receptors. The Journal of organic chemistry. 2024. 89. 6. 4128-4133
Noritada Matsuo, Yukimi Sugisaka, Shiori Aoyama, Makoto Ihara, Harue Shinoyama, Munetaka Hosokawa, Yoshinobu Kamakura, Daisuke Tanaka, Yoo Tanabe, Kazuhiko Matsuda. Creating Pyrethrin Mimetic Phosphonates as Chemical Genetics Tools Targeting the GDSL Esterase/Lipase TcGLIP to Investigate Pyrethrin Biosynthesis. Journal of medicinal chemistry. 2023. 66. 12. 7959-7968
Steven D Buckingham, Makoto Ihara, David B Sattelle, Kazuhiko Matsuda. Mechanisms of Action, Resistance and Toxicity of Insecticides Targeting GABA Receptors. Current medicinal chemistry. 2017. 24. 27. 2935-2945
Makoto Ihara, Steven D Buckingham, Kazuhiko Matsuda, David B Sattelle. Modes of Action, Resistance and Toxicity of Insecticides Targeting Nicotinic Acetylcholine Receptors. Current medicinal chemistry. 2017. 24. 27. 2925-2934
Paraherquamide A の C. elegans ニコチン性アセチルコリン受容体サブタイプ選 択性の分子機構
(2023 年度 日本農芸化学会 中部・関西支部合同大会 (中部支部:第 196 回例会)(関西支部:第 527 回講演会) 2023)
Determinants of sub-type selectivity of Paraherquamide A on Caenorhabditis elegans nicotinic acetylcholine receptors
(Control of Human Disease Vectors, Pests and Parasites 2023)
Paraherquamide A のC. elegans ニコチン性アセチルコリン受容体に対するサブタイプ 選択性の分子メカニズム
(日本農薬学会2023年度大会 2023)
