Rchr
J-GLOBAL ID:200901005425042890   Update date: Jul. 29, 2024

HIRASAKI Masataka

ヒラサキ マサタカ | HIRASAKI Masataka
Affiliation and department:
Job title: Lecturer
Research field  (4): Tumor diagnostics and therapeutics ,  Genomics ,  Molecular biology ,  Medical biochemistry
Research keywords  (6): ゲノム医療・診断 ,  ES細胞の未分化性の維持 再生医療 ,  バイオマーカー ,  再生医療 ,  腫瘍 ,  ES細胞の未分化性の維持
Research theme for competitive and other funds  (15):
  • 2021 - 2024 Mbd3によるPrimed型多能性幹細胞の維持と分化の方向性の決定機構の解明
  • 2022 - 2023 Autophagy関連遺伝子の SNV(single nucleotide variant)を基に食道癌の術前補助化学療法の治療選択を可能とする
  • 2020 - 2022 Epi幹細胞の維持と分化の方向性の決定におけるMbd3の機能
  • 2021 - 2022 Mbd3によるエピブラスト幹細胞の幹細胞性維持と分化の方向性の決定機構の解明
  • 2020 - 2021 根治切除大腸癌の術後補助化学療法の有効性をAutophagy関連遺伝子の SNV(single nucleotide variant)で予測する
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Papers (35):
  • Takehiro Nogi, Kousuke Uranishi, Ayumu Suzuki, Masataka Hirasaki, Tina Nakamura, Tomiei Kazama, Hiroshi Nagasaka, Akihiko Okuda, Tsutomu Mieda. Similarity and dissimilarity in alterations of the gene expression profile associated with inhalational anesthesia between sevoflurane and desflurane. PloS one. 2024. 19. 3. e0298264
  • Yoshiaki Mihara, Masataka Hirasaki, Yosuke Horita, Takashi Fujino, Hisayo Fukushima, Yasuo Kamakura, Kousuke Uranishi, Yasumitsu Hirano, Shomei Ryozawa, Masanori Yasuda, et al. PTEN-induced kinase 1 gene single-nucleotide variants as biomarkers in adjuvant chemotherapy for colorectal cancer: a retrospective study. BMC gastroenterology. 2023. 23. 1. 339-339
  • Yasuhiro Takenaka, Masataka Hirasaki, Ikuo Inoue, Masaaki Ikeda, Hisayuki Ohata, Yoshihiko Kakinuma. Transcriptome analyses of mouse cardiac myocytes and non-cardiomyocytes: postmitotic vs. proliferative cells. 2023
  • Yasuhiro Takenaka, Ikuo Inoue, Masataka Hirasaki, Masaaki Ikeda, Yoshihiko Kakinuma. Temporal inhibition of the electron transport chain attenuates stress-induced cellular senescence by prolonged disturbance of proteostasis in human fibroblasts. The FEBS journal. 2023. 290. 15. 3843-3857
  • Hitoshi Inoue, Masataka Hirasaki, Yasunao Kogashiwa, Yutaka Nakachi, Kiyomi Kuba, Yasuhiro Ebihara, Mitsuhiko Nakahira, Masanori Yasuda, Akihiko Okuda, Masashi Sugasawa. Identification of novel oncogenes in oral cancer among elderly nonsmokers. Clinical and experimental dental research. 2023. (in press)
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Patents (2):
  • 癌の補助化学療法の予後を予測する方法及びそれに使用される試薬
  • HPV陰性中咽頭扁平上皮癌の放射線感受性予測を目的としたbiomarkerの発見
Lectures and oral presentations  (52):
  • マウス心筋細胞および非心筋細胞のトランスクリプトーム解析:個体老化における増殖停止細胞と増殖性細胞の比較
    (第100回 日本生理学会 2023)
  • 細胞老化に伴って蓄積する老化関連凝集体の機能解析
    (第45回 分子生物学会年会 2022)
  • Mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) arising from long-segment Barrett esophagus
    (2022)
  • PTEN-induced kinase 1 gene single nucleotide variants as biomarkers in adjuvant chemotherapy for colorectal cancer
    (2022)
  • Mixed neuroendocrine-non-neuroendocrine neoplasm (MiNEN) arising from long-segment Barrettʼs esophagus showing exceptionally aggressive clinical behavior
    (第26回日本臨床内分泌病理学会学術集会 2022)
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Education (3):
  • 2002 - 2007 Osaka University Graduate School of Engineering Department of Biotechnology,
  • 2000 - 2002 Ehime University Graduate School of Agriculture Department of Biological Resources
  • 1996 - 2000 Fukuyama University Faculty of Engineering
Professional career (1):
  • 工学 (大阪大学)
Work history (7):
  • 2020/04 - 現在 埼玉医科大学 医学部 ゲノム基礎医学 講師
  • 2020/04 - 現在 Saitama Medical University International Medical Center Department of Clinical Cancer Genomics
  • 2012/04 - 2020/03 埼玉医科大学 ゲノム医学研究センター ゲノム医学研究センター 助教
  • 2012/04 - 2020/03 Saitama Medical University Research Center for Genomic Medicine Division of Developmental Biology
  • 2008/04 - 2012/03 Saitama Medical University Faculty of Medicine Molecular Biology
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Awards (1):
  • 2019/12 - 埼玉医科大学 学内グラント研究費 Mbd3によるエピブラスト幹細胞の幹細胞性維持と分化の方向性の決定機構の解明
Association Membership(s) (3):
日本遺伝子診療学 ,  日本癌学会 ,  The Molecular Biology Society of Japan
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