Ohshima Koichi

Research field (1)： Human pathology

Research keywords (2)： HTLV-I EBV ホジキンリンパ腫 , 悪性リンパ腫

Research theme for competitive and other funds (37)：

2022 - 2025 Construction of a disease type discriminator based on cell histomorphology and realization of a platform for atypicality analysis of malignant lymphomas
2019 - 2024 本邦CLLの病態解明に基づく簡便な新規診断法の確立
2020 - 2023 Microenviroment in classical Hodgkin lymphoma and Hodgkin-like ATLL
2018 - 2021 Immune microenvironment and prognostic factors in pediatric peripheral T-cell lymphomas
2017 - 2020 TERT promoter gene mutations in PTCL-NOS

2016 - 2019 Differential diagnosis of Japanese patients with CLL and related disorders

2016 - 2019 The lymphoma microenvironment is a novel therapeutic target in the treatment of patients with B-cell lymphoma

2015 - 2018 Genetic alterations of aggressive NK cell leukemia and identification of molecular target candidates

2015 - 2018 Analysis of JAK-STAT pathway in diffuse large B-cell lymphoma

2014 - 2017 Virus antigen specific CTL in HTLV-1 and EBV associated lymphoma

2012 - 2015 Study on the comprehensive treatment strategy of hemophagocytic syndrome

2012 - 2015 The immune escape mechanism in primary central nervous system lymphomas: the role of the endothelin B receptor

2010 - 2012 The confirmation of HTLV-1 associated Hepatitis

2010 - 2012 Basic and clinical study for the protection and the treatment of gastric malignant lymphoma.

2009 - 2011 Research on the pathogenesis and treatment of Epstein-Barr virusassociated intractable diseases

2008 - 2010 The analysis of chemokines and Epstein-Barr virus in the tumor genesis of primary central nervous system lymphomas

2008 - 2010 Clinocopathological analysis of HTLV-I associated genes of HBZ and tax in the tumor genesis of ATLL

2006 - 2008 Staging of mediastinal and hilar lymph node metastases from lung cancer: Evaluation with STIR and diffusion-weighted MRI

2005 - 2006 Role of chemokine and chemokine receptor in T-cell lymphoma and HTLV-I associated lymph node lesions.

2004 - 2004 MALTリンパ腫における末梢血CD20、CXCR3陽性細胞の解析

2003 - 2004 Prediction of CHOP therapy resistance in diffuse large B cell lymphoma: a genome-wide cDNA microarray analysis.

2002 - 2004 THE INVERACTION OF VEGF, ANGIOPOIETIN, AND HYPOXIA IN ANGIOGENESIS OF THE GYNECOLOGIC CANCER

2002 - 2004 Basic and clinical study to investigate new treatment strategy for MALT lymphoma

2000 - 2002 Patho- and morphogenesis of Kikuchi's disease

1999 - 2001 The role of HTLV-1 and EBV infection on the development of malignant lymphoma in Okinawa

1999 - 2001 HTLV-I associated lymph node and HTLV-I pathogenesis.

1999 - 2000 EXPERIMENTAL ANTI-ANGIOGENIC THERAPY FOR UTERINE SARCOMA

1997 - 1999 Pathogenesis and occurrence mechanisms of Kikuchi's disease (histiocytic necrotizing lymphadentis)

1996 - 1998 HTLV-I association between T-cell lymphoma and genomic changes in HTLV-I endemic areas

1995 - 1996 The study of characterization and tumor cell origin of natural killer (NK) cell lymphoma.

1995 - 1996 Kikuchi's disease : Pathogenesis and mechanisms of progression

1992 - 1994 Pathogenesis and mechanism of occurrence of Kikuchi-Fujimoto disease

1993 - 1993 ATLLの発癌様式及び発現系

1989 - 1991 Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease)

血液腫瘍の診断発生病理

悪性リンパ腫

Malignant lymphoma

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Papers (444)：

Tatsuzo Mishina, Hiroaki Miyoshi, Mai Takeuchi, Kohta Miyawaki, Kazutaka Nakashima, Kyohei Yamada, Mayuko Moritsubo, Kanako Inoue-Mitsuyama, Yasumasa Shimasaki, Teppei Imamoto, et al. Co-expression of regulatory B-cell markers, transforming growth factor β and interleukin-10 as a prognostic factor in diffuse large B-cell lymphoma. Pathology, research and practice. 2024. 254. 155117-155117
Yasumasa Shimasaki, Hiroaki Miyoshi, Keisuke Kawamoto, Noriaki Yoshida, Tatsuzo Mishina, Kazutaka Nakashima, Teppei Imamoto, Takeshi Sugio, Eriko Yanagida, Takeharu Kato, et al. Clinicopathological comparison between PTCL-TBX21 and PTCL-GATA3 in Japanese patients. Cancer medicine. 2024
Miharu Nagaishi, Hiroaki Miyoshi, Mauricio Kugler, Kensaku Sato, Kei Kohno, Mai Takeuchi, Kyohei Yamada, Takuya Furuta, Noriaki Hashimoto, Ichiro Takeuchi, et al. The detection of neoplastic cells by objective cytomorphological parameters in malignant lymphoma. Laboratory Investigation. 2023. 100302-100302
Ken Tanaka, Hiroaki Miyoshi, Keisuke Kawamoto, Yasumasa Shimasaki, Kazutaka Nakashima, Teppei Imamoto, Kyohei Yamada, Mai Takeuchi, Mayuko Moritsubo, Takuya Furuta, et al. Clinicopathological analysis of CD47 and signal regulatory protein alpha expression in myeloid sarcoma patients: CD47 expression is a favourable prognostic factor. Pathology. 2023
Mayuko Moritsubo, Takuya Furuta, Junko Miyoshi, Satoru Komaki, Kiyohiko Sakata, Hiroaki Miyoshi, Motohiro Morioka, Koichi Ohshima, Yasuo Sugita. Increased expression of leucine-rich α-2 glycoprotein 1 as a predictive biomarker of favorable progression-free survival in meningioma. Neuropathology : official journal of the Japanese Society of Neuropathology. 2023

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MISC (250)：

山田悠一, 友川拓也, 遠藤友志郎, 加藤丈晴, 佐藤信也, 安東恒史, 澤山靖, 新野大介, 今泉芳孝, 波多智子, et al. 医原性免疫不全関連リンパ腫として発症した形質芽球性リンパ腫. 日本リンパ網内系学会会誌. 2021. 61. 94-94
一瀬将広, 加藤丈晴, 渕上麻衣, 渡辺春香, 山田悠一, 藤岡真知子, 鶴田一人, 佐藤信也, 安東恒史, 澤山靖, et al. Intravascular large B-cell lymphoma during the course of smoldering myeloma. 日本血液学会学術集会抄録(Web). 2021. 83rd. OS3-4
Taisuke Narazaki, Motoaki Shiratsuchi, Takamitsu Matsushima, Mariko Tsuda, Yasuhiro Tsukamoto, Hiroki Muta, Toru Masuda, Daisaku Kimura, Akiko Takamatsu, Hidetaka Yamamoto, et al. Clinico-pathological characteristics of primary adrenal lymphomas-potential efficacy of autologous stem cell transplantation. Leukemia and Lymphoma. 2020. 61. 6. 1516-1518
Mai Takeuchi, Hiroaki Miyoshi, Kazutaka Nakashima, Keisuke Kawamoto, Kyohei Yamada, Eriko Yanagida, Hiroko Muta, Mayuko Moritsubo, Takeshi Umeno, Takaharu Suzuki, et al. Comprehensive immunohistochemical analysis of immune checkpoint molecules in adult T cell leukemia/lymphoma. Annals of hematology. 2020. 99. 5. 1093-1098
島崎裕正, 島崎裕正, 三好寛明, 柳田恵理子, 鈴木隆晴, 河本啓介, 大島孝一. PTCL-TBX21とPTCL-GATA3の分類および臨床病理学的検討. 日本血液学会学術集会抄録(Web). 2020. 82nd

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Books (2)：

悪性リンパ腫の基礎と臨床押味和夫編、新WHO分類
医薬ジャーナル 2003
骨髄病理アトラス
分光堂 2003

Education (2)：

- 1984 Kyushu University School of Medicine
- 1984 Kyushu University Faculty of Medicine

Professional career (1)：

(BLANK)

Association Membership(s) (3)：

内科学会 , 日本血液学会 , 病理学会

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