Rchr
J-GLOBAL ID:200901005618406830
Update date: Nov. 21, 2024
Nonoguchi Naosuke
ノノグチ ナオスケ | Nonoguchi Naosuke
Homepage URL (1):
http://kaken.nii.ac.jp/d/r/70388263.ja.html
Research field (3):
Neurosurgery
, Radiology
, Nutrition and health science
Research keywords (14):
Brain tumor surgery
, Brain tumor pathology
, 脳腫瘍遺伝子解析
, Photodynamic diagnosis/therapy
, 脳虚血
, 錐体神経細胞
, 骨髄間葉系細胞
, 低酸素負荷
, HGF
, 幹細胞移植
, 神経保護
, 骨髄細胞
, 脳腫瘍
, 骨髄細胞移植
Research theme for competitive and other funds (22):
- 2024 - 2027 Elucidation of the antitumor effect of diacylglycerol kinase (DGK) inhibition in glioblastoma
- 2024 - 2027 グリオーマ浸潤におけるlamellipodiaの解析とα-actinの制御機構の解明
- 2022 - 2025 脊髄神経膠腫に対するホウ素中性子捕捉療法の確立に向けた基盤研究
- 2021 - 2024 悪性神経膠腫・悪性髄膜種において新規分子標的となる転写キメラの同定とその機能解析
- 2021 - 2024 Elucidation of the relationship between infiltration ability and ACTC1 and its molecular mechanism in malignant meningioma
- 2020 - 2023 Elucidation of pathophysiology of pseudoprogression for brain tumors
- 2020 - 2023 Analysis of glioma invasion mechanisms and development of pioneering therapies targeting invasive potential
- 2020 - 2023 Investigation regarding the progress of therapeutic effect of BNCT using folate receptor-targeted boron compound which be administered by convection enhanced delivery
- 2018 - 2021 Predictive map for PDT effect, malignancy and biological characteristics in malignant brain tumor
- 2017 - 2020 Translocator protein (TSPO) targetting boron deliverly and neutron capture therapy against malignant brain tumors
- 2017 - 2020 Search for biomarkers of sensitivity to MTX monotherapy in primary central nervous system lymphoma
- 2017 - 2020 Novel diagnostic examination and treatment of radiation necrosis based on molecular pathological mechanism
- 2017 - 2019 Usefulness of a super selective arterial infusion therapy of a novel boronated porphyrin for BNCT and PDT
- 2016 - 2019 Drug repositioning for mitigation of radiation-induced lung injury
- 2014 - 2017 Analysis of pathophysiology of brain radiation necrosis and establishment of novel treatment strategy
- 2014 - 2017 Overcome of intractable radiation necrosis. Bevacizumab therapy and beyond bevacizumab
- 2011 - 2011 Patho-physiology of the radiation necrosis in the brain
- 2008 - 2010 Usefullness of novel boronated porphyrins for both BNCT and PDT
- 2008 - 2009 Induction of pyramidal neuronal cells from bone marrow stromal stemcells and application for autologous transplantation against the cerebral infarction.
- 2006 - 2007 短半減期エリスロポイエチン誘導体とFGF2を用いた神経再生と神経保護の研究
- 2005 - 2006 神経栄養遺伝子を導入した骨髄細胞の移植による神経再生と神経保護を目指した研究
- 2005 - 2006 Regeneration of neurons and vessels using bone marrow cells and gene delivery
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Papers (153):
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川端 信司, 柏木 秀基, 野々口 直助, 古瀬 元雅, 高見 俊宏, 宮武 伸一, 鰐渕 昌彦. 【髄膜腫の現在-最新の知識を活かした最善の治療のために】髄膜腫に対する集学的治療 髄膜腫に対する放射線治療の位置付け. Neurological Surgery. 2024. 52. 4. 782-793
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川端 信司, 江座 健一郎, 藤川 喜貴, 辻野 晃平, 柏木 秀基, 野々口 直助, 古瀬 元雅, 高見 俊宏, 鰐渕 昌彦. 専門医に求められる最新の知識 脳腫瘍 BNCT(ホウ素中性子捕捉療法)の開始と今後への期待. 脳神経外科速報. 2024. 34. 4. 486-491
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Shinji Kawabata, Hideki Kashiwagi, Naosuke Nonoguchi, Motomasa Furuse, Toshihiro Takami, Shin-Ichi Miyatake, Masahiko Wanibuchi. [Defining the Role of Radiotherapy in Meningioma Treatment]. No shinkei geka. Neurological surgery. 2024. 52. 4. 782-793
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Yoshiki Fujikawa, Shinji Kawabata, Kohei Tsujino, Hironori Yamada, Hideki Kashiwagi, Ryokichi Yagi, Ryo Hiramatsu, Naosuke Nonoguchi, Toshihiro Takami, Akinori Sasaki, et al. Boron neutron capture therapy delays the decline in neurological function in a mouse model of metastatic spinal tumors. Cancer science. 2024
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Yoshiki Fujikawa, Naokado Ikeda, Kosuke Sakai, Naoki Omura, Ryokichi Yagi, Ryo Hiramatsu, Masahiro Kameda, Naosuke Nonoguchi, Motomasa Furuse, Shinji Kawabata, et al. Postoperative Airway Management after Anterior Cervical Spine Surgery: Retrospective Neurosurgical Multicenter Study. Neurologia medico-chirurgica. 2024. 64. 5. 205-213
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MISC (225):
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小坂拓也, 福村匡央, 二村元, 矢木亮吉, 平松亮, 亀田雅博, 野々口直助, 古瀬元雅, 川端信司, 高見俊宏, et al. 当院での脳腫瘍による重度視力低下症例における術後視機能の解析. 日本脳神経CI学会総会プログラム・抄録集. 2024. 47th
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山田浩徳, 亀田雅博, 江座健一郎, 蒲原明宏, 矢木亮吉, 平松亮, 野々口直助, 古瀬元雅, 川端信司, 高見俊宏, et al. A case of coronal synostosis evaluated by mid-sagittal vector analysis. 小児の脳神経(Web). 2024. 49. 2
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香月里奈, 亀田雅博, 梶本宜永, 池田直廉, 柏木秀基, 福尾祐介, 小坂拓也, 福村匡央, 矢木亮吉, 平松亮, et al. A case of VP shunt implanted in childhood for congenital hydrocephalus, leading to shunt dysfunction in adulthood. 小児の脳神経(Web). 2024. 49. 2
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亀田雅博, 野々口直助, 柏木秀基, 福尾祐介, 小坂拓也, 高井聡, 古瀬元雅, 川端信司, 高見俊宏, 鰐渕昌彦. A case of Giant cell GBM treated with pembrolizumab based on the results of a cancer gene panel test. 小児の脳神経(Web). 2024. 49. 2
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川端信司, 江座健一郎, 藤川喜貴, 辻野晃平, 柏木秀基, 野々口直助, 古瀬元雅, 高見俊宏, 鰐渕昌彦. Provision and Prospect of Boron neutron capture therapy: BNCT. 脳神経外科速報. 2024. 34. 4
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Work history (7):
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