Kunugi Hiroshi

クヌギヒロシ | Kunugi Hiroshi

Affiliation and department：
Job title： Professor and Chair
Other affiliations (1)：

National Center of Neurology and Psychiatry

Homepage URL (1)： http://www.teikyo-psy.com/

Research field (3)： Psychiatry , Nutrition and health science , Genetics

Research keywords (22)： mood disorders , nutritional psychiatry , cerebrospinal fluid , gut microbiota , life style , 脳由来神経栄養因子 , stress , 視床下部ー下垂体-副腎系 , heart rate variability , 統合失調症 , プレパルス抑制テスト , モデル動物 , Alzheimer's disease , 遺伝子多型 , psychopharmacology , 神経科学 , VEGF , cognitive function , 分子遺伝学 , 海馬 , 神経栄養因子 , 神経発達障害

Research theme for competitive and other funds (27)：

2022 - 2025 Creation and clinical application of 3D brain barrier chips using human iPS cells
2021 - 2024 [1-13C]Trpと[1-13C]5-HTPの合成とうつ病の客観的診断法の開発
2018 - 2023 Study of drug discovery and biomarker for depression based on glial antidepressant receptor (LPA1)
2019 - 2022 Research on molecular and brain basis for sensorimotor gating dysfunction
2016 - 2019 A personality-based examination of the health-illness continuum: association with gene expression profiles

2016 - 2018 Development of a novel biomarker and treatment for major depressive disorder focusing on the ethanolamine in the cerebrospinal fluid

2015 - 2018 Translational study on exercise program for promoting vitality of body and mind: unravel the mechanism of enhancing motivation and cognitive function in brain.

2015 - 2018 Study on the serotonin kynurenine hypothesis by the stable isotope breath test in mood disorder

2015 - 2017 Study on the clinical use of (13)C-tryptophan breath test in depressive disorder

2015 - 2017 Quantitative analysis of lysophosphatidic acid (LPA) in serum and cerebrospinal fluid of depressed patients

2013 - 2016 Development of biomarkers for functional psychoses based on multiple omics analyses

2012 - 2013 うつ病の発症におけるCARTの役割;人と動物を対象とした研究

2010 - 2011 The application of stable isotope breath test and biopterin administration to the evaluation and treatment of psychiatric disorders

2008 - 2011 Role of neurotrophin receptor p75 in psychiatric diseases

2005 - 2009 A Search for Risk Genes of Psychiatric Disorders

2007 - 2008 Search and functional analysis for candidate gene of schizophrenia by CGH array method.

2006 - 2008 Molecular genetic study on the pathophysiology of psychiatric disorders based on the role of PACAP

2003 - 2005 プレパルス抑制検査を用いた統合失調症の病態の解明と診断法の開発

2003 - 2004 メチル化によるエピジェネティクなゲノム変化と統合失調症との関連解析

2002 - 2003 Phylogenetic analyses of the HLA-DRB1 gene based on the DR haplotypes

2001 - 2002 Polymorphism screening and association analysis of neurotrophic factor genes in neuropsychiatric diseases

1999 - 2002 Genome Scan of Candidate Region of Schizophrenia using DNA Pooling Method

2000 - 2000 精神分裂病関連遺伝子の解明

1999 - 2000 Role of neurotrophic factors in the susceptibility to schizophrenia and its brain abnormalities

1997 - 1999 Study of genetic markers on the short arm of the chromosome 6 (6p) in schizophrenia : analysis of schizophrenia susceptibility gene

1997 - 1998 Relationships between polymorphisms of genes encoding neurotrophic factors and neurodevelopment in schizophrenia

1995 - 1997 Molecular genetics study of schizophrenia based on neurodevelopmental hypothesis

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Papers (618)：

功刀浩. うつ状態患者に対するウエアラブルモニター活用の可能性. 最新精神医学. 2025. 30. 1. 39-43
Takako Enokida, Kotaro Hattori, Kaori Okabe, Takamasa Noda, Miho Ota, Noriko Sato, Shintaro Ogawa, Megumi Tatsumi, Mikio Hoshino, Hiroshi Kunugi, et al. Possible association of elevated CSF IL-6 levels with anxiety and frustration in psychiatric disorders. Psychiatry and clinical neurosciences. 2024. 78. 12. 792-799
功刀浩. 栄養からとらえるうつと不安. Depression Strategy. 2024. 14. 4. 1-4
功刀浩. うつ病と栄養. 食器と容器. 2024. 65. 10. 664-669
Takako Enokida, Kotaro Hattori, Miho Ota, Megumi Tatsumi, Shinsuke Hidese, Noriko Sato, Mikio Hoshino, Hiroshi Kunugi. Correlation between myelin basic protein levels in cerebrospinal fluid and motor speed in patients with schizophrenia. Neuropsychopharmacology Reports. 2024

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MISC (250)：

功刀浩. メンタルヘルスと栄養学. 明日へ(東京人権啓発企業連絡会). 2024. 71. 12-15
功刀浩(監修). 精神疾患と腸内細菌叢のかかわりを探る. Trends in Psychiatric Science. 2024. 1-3
功刀浩. この書籍から学んだこと:精神科医による書籍紹介. CNS情報Plus. 2024. 31. 8-8
功刀浩. ストレスでうつ病になるのはどうしてですか?. CLINICAL NEUROSCIENCE. 2023. 41. 10. 1375-1375
功刀浩. うつを予防・改善するための食生活. 中学保健ニュース. 2023. 1886

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Books (24)：

気分の落ち込みやストレスを感じやすいときに見直したい食事の重要性
ハルメク 2024
心を整える・元気脳をつくるまいにちメンタルヘルス:心が腫れるライフスタイル改善のすすめ
東京法規出版 2024
食生活習慣とうつ病リスク
医歯薬出版、東京 2023
薬だけに頼らずうつがみるみる遠ざかる食べ方大全
文響社 2023
美味しく食べてメンタルケア : 精神栄養学最前線
中央労働災害防止協会 2022 ISBN:9784805920473

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Lectures and oral presentations (117)：

こころの健康に良い生活習慣(食事・運動・睡眠)
(埼玉県主催働き世代の健康管理研修会、川越地方庁舎4階大会議室 2025)
こころの病気と腸内細菌の深い関係
(東京理科大学薬学ベーシックコース薬物治療アップトゥデート講座6 2025)
より良い眠りを得るための睡眠学と睡眠薬の進歩
(東京理科大学薬学ベーシックコース薬物治療アップトゥデート講座6 2025)
気分障害治療における食生活と運動
(国立精神・神経医療研究センター気分障害センター市民公開講座 2024)
Nutritional approaches to common mental disorders
(Monash University Nutrition and Mental Health unit Lecture 2024)

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Education (2)：

1982 - 1986 東京大学医学部医学科
1980 - 1982 The University of Tokyo College of Arts and Sciences

Professional career (1)：

Ph.D. (The University of Tokyo)

Work history (7)：

2021/04 - 現在 Teikyo University School of Medicine Department of Psychiatry Professor and Chair
2020/04 - 現在 National Center of Neurology and Psychiatry
2020/04 - 現在 Teikyo University
2020/04 - 現在 National Center of Neurology and Psychiatry Department of Mental Disorder Research Visiting researcher
2002/05 - 2020/03 National Center of Neurology and Psychiatry Department of Mental Disorder Research Director

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Association Membership(s) (17)：

Japanese Society for Child and Adolescent Psychiatry , 東京精神医学会 , Japanese Society of Nutrition and Food Science , International College of Neuropsychopharmacology , Japanese Clinical Nutrition Association , Japanese Society of Clinical Nutrition , Japanese Society of Mood Disorders , 日本統合失調症学会 , 日本臨床精神神経薬理学会 , Japanese Society of Neuroscience , Japanese Society of Sleep Research , Japanese Society of Geriatric Psychiatry , Japanese Society of Biological Psychiatry , 日本社会精神医学会 , Japanese Society of General Hospital Psychiatry , Japanese Society of Psychiatry and Neurology , 日本神経精神薬理学会

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